Yu Wu

ORCID: 0000-0001-8055-8327
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Urinary Bladder and Prostate Research
  • Prostate Cancer Diagnosis and Treatment
  • Hormonal and reproductive studies
  • Ophthalmology and Eye Disorders
  • Sperm and Testicular Function
  • Ovarian function and disorders
  • Assisted Reproductive Technology and Twin Pregnancy
  • Urological Disorders and Treatments
  • Ocular Surface and Contact Lens
  • Balance, Gait, and Falls Prevention
  • Urinary and Genital Oncology Studies
  • Advanced Differential Geometry Research
  • Prenatal Screening and Diagnostics
  • Reproductive System and Pregnancy
  • Acute Myocardial Infarction Research
  • Urologic and reproductive health conditions
  • Pituitary Gland Disorders and Treatments
  • Thyroid Cancer Diagnosis and Treatment
  • Renal and related cancers
  • Ectopic Pregnancy Diagnosis and Management
  • Reproductive Health and Technologies
  • Genetic Syndromes and Imprinting
  • Sexual Differentiation and Disorders
  • Cardiac Imaging and Diagnostics

Shanghai Jiao Tong University
2014-2025

Shanghai Ninth People's Hospital
2018-2025

Shanghai Institute of Hematology
2020-2025

Shandong University
2025

China Rehabilitation Research Center
2025

Wenzhou University
2025

Wuhan Asia Heart Hospital
2024

Shuguang Hospital
2020-2024

Wuhan University
2024

XinHua Hospital
2011-2024

The goal of this study was to assess the association between endometrial thickness on chorionic gonadotropin (hCG) day and in vitro fertilization embryo transfer (IVF-ET) outcome normal responders after GnRH antagonist administration. A retrospective cohort performed with administration from January 2011–December 2013. Patients were divided into four groups according thickness, as follows: <7 mm (group 1), > = 7- < 8 2), 8- 14 3), =14 4). total 2106 cycles analyzed. pregnancy rate (PR)...

10.1186/1477-7827-12-96 article EN cc-by Reproductive Biology and Endocrinology 2014-10-09

Numerous genes have been associated with multiple morphological abnormalities of the sperm flagella (MMAF), which cause severe asthenozoospermia and lead to male infertility, while causes approximately 50% MMAF cases remain unclear. To reveal genetic in an infertile patient, whole-exome sequencing was performed screen for pathogenic genes, electron microscope used flagellar ultrastructure. A novel heterozygous missense mutation outer dense fiber protein 2 (ODF2) gene detected, inherited from...

10.4103/aja202183 article EN cc-by-nc-sa Asian Journal of Andrology 2022-01-28

Abstract High myopia stands as the primary cause of blindness globally, with cataract emerging one most prevalent complications. However, underlying mechanism high myopic remains unknown. The lens capsule is basement membrane enclosing lens. In this study, we hypothesized tissue‐derived extracellular vesicles (Ti‐EVs) play a vital role in formation cataract. Ti‐EVs were collected from and age‐related patients during surgery, isolated by ExoDisc. Then, performed proximity barcoding assay for...

10.1002/viw.20240140 article EN cc-by View 2025-02-13

On May 14th, 2022, a racially motivated mass shooting occurred in predominantly Black neighborhood Western New York. The trauma brought fresh anguish to fraught social landscape already shaken by COVID-19 and resurgent racism. This paper explores the formation of campus meditation group that emerged light tragedy prolonged pandemic suffering, its members’ journeys healing, self-discovery, transformation. While scholars have critiqued neoliberal higher education for producing...

10.25035/jche.02.02.07 article EN Journal of Contemplative and Holistic Education 2025-01-01

The current research aims to evaluate the risk factors of urethrocutaneous fistula after hypospadias surgery among youth in China.One hundred twenty patients were enrolled our study. All them defined as Tanner 4 or 5. information collected from participants include age, urethral operation history, urinary comorbidities before operation, urine test body temperature and type surgical repair, chordee degree, defect length whether received vesicostomy not. Independent t test, chi-square...

10.1186/s12894-018-0366-z article EN cc-by BMC Urology 2018-07-24

Abstract Purpose The purpose of this article is to investigate the characteristics Th1-cell and Th17-cell lineages for very severe Graves orbitopathy (GO) development. Methods Flow cytometry was performed with blood samples from GO disease (GD) patients healthy controls, explore effector T-cell phenotypes. Lipidomics conducted serum before after glucocorticoid (GC) therapy. Immunohistochemistry Western blotting were used examine orbital-infiltrating Th17 cells or in vitro models...

10.1210/clinem/dgaa124 article EN The Journal of Clinical Endocrinology & Metabolism 2020-03-16

Summary Transmembrane activator and calcium modulator cyclophilin ligand interactor-immunoglobulin (TACI-Ig) is a human fusion protein that binds neutralizes both B lymphocyte stimulator (BLyS), cytokine shown to be key regulator of cell maturation, proliferation survival, proliferation-inducing (APRIL). Rat adjuvant arthritis (AA) an experimental animal model rheumatoid (RA), which mainly dependent on T cells neutrophil-mediated production. The purpose the present study was investigate...

10.1111/j.1365-2249.2010.04293.x article EN Clinical & Experimental Immunology 2010-12-13

Abstract Background Current studies suggest that cardiac troponin (cTn) forms in the circulation may vary different clinical scenarios. Our aim was to design a combination of cTn assays specific main and evaluate their analytical performance. Methods We developed immunoassays for measuring (1) long-cTnT cTnI-cTnT-TnC (ITC) ternary complex, with cTnT long form without cleavage at C-terminal amino acids residue 189–223, designated “long-cTnT ITC complex assay;” (2) both plus short-cTnT...

10.1093/clinchem/hvae182 article EN Clinical Chemistry 2024-10-15

Summary Herein, we report the clinical outcomes following intracytoplasmic sperm injection ( ICSI ) with cryopiece cryopreserved rare human spermatozoa from severe male factor infertility patients. We established a novel system on basis of previous studies. In this study, 126 four patients non‐obstructiveazoospermia NOA or oligozoospermia were stored in and then thawed day oocyte retrieval, 88 (83%) recovered 47.5% (38 80) motile rate. Routine performed enrolled 30 MII oocytes their spouse...

10.1111/andr.12380 article EN Andrology 2017-06-21

Background: Recent studies have reported a wide spectrum of ocular surface injuries in the context autoimmune reactions Graves' orbitopathy (GO). Increased expression inflammatory mediators tears GO patients suggests that lacrimal glands could be target for immune responses. However, immunophenotype microenvironment is not known. This study aimed to elucidate pathological changes glands. Methods: In this case-control study, were surgically collected from who underwent orbital decompression...

10.1089/thy.2021.0671 article EN Thyroid 2022-04-26

Background: Graves' orbitopathy (GO) is a disfiguring and sight-threatening autoimmune disease. Previous studies have shown the infiltration of macrophages in GO orbital connective tissues. However, immunophenotypes their modulatory effects on fibroblasts (OFs) not been examined so far. In this study, we sought to determine pathophysiology GO. Methods: case-control tissues collected from 40 patients 20 healthy controls were immunohistochemically stained for cytokines macrophage cell surface...

10.1089/thy.2022.0254 article EN Thyroid 2023-01-09

Abstract Background Increased cardiac troponin (cTn) concentrations occur in acute myocardial injury and chronic diseases. Characterization of cTn composition the circulation may assist differentiating etiologies injury. Our goal was to study kinetics patients following type 1 infraction (T1MI), procedures, heart diseases establish relationship between clinical diagnosis. Methods Plasma samples were collected from 201 with T1MI, 78 undergoing surgeries, 218 cardiomyopathy or failure. Major...

10.1093/clinchem/hvae200 article EN Clinical Chemistry 2024-12-17

Backgrounds Previous studies suggested that singletons from frozen-thawed embryo transfer (FET) were associated with higher risk of large, post-date babies and adverse obstetrical outcomes compared to fresh natural pregnancy. No data available revealed whether the perinatal aberrantly high progesterone level different endometrium preparations in HRT-FET cycle. This study aimed compare impact intramuscularly vaginally regimens on neonatal cycles. Methods A total 856 cycles a fertility center...

10.3389/fendo.2020.539427 article EN cc-by Frontiers in Endocrinology 2020-12-04

Leiomyomas are common benign tumors in the uterus. They rarely seen vaginal wall leading to pressure symptoms on urinary tract. Here we present a case of 44-year-old Chinese woman, who had accepted hysterectomy, with painless paraurethral mass associated local discomfort. A complete surgical excision was performed by route, and histology report confirmed diagnosis leiomyoma.

10.1016/j.eucr.2015.02.004 article EN cc-by-nc-nd Urology Case Reports 2015-03-27

// Linlin Yang 1, 2, * , Qiaoying Lv 3, Wei Chen 1 Jian Sun Yu Wu Yiying Wang 4 Xiong 2 Xiaojun 3 and Zhenbo Zhang The Reproductive Medicine Center of Department Obstetrics Gynecology, Shanghai General Hospital, Jiao Tong University, 200080, China First People's Baoshan Branch, 201900, Gynecology Hospital Fudan 200011, Henan Province Zhengzhou 450000, These authors have contributed equally to this work Correspondence to: Zhang, email: zhangzhenbozzb@aliyun.com Keywords: embryonic culture...

10.18632/oncotarget.18852 article EN Oncotarget 2017-06-29

It is human nature to swing their arms at the frequency of leg motion during walking, but contribution arm dynamic stability segments was poorly understood. Based on nonlinear time series analysis method, objective this study investigate effects in three conditions (natural, active and restricted swing) spine lower extremity joints, further assess relation with age. Gait experiments were carried out for 10 young 8 middle-aged healthy volunteers while walking natural, swing. The maximum...

10.1109/embc.2012.6347075 article EN Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2012-08-01
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