- GaN-based semiconductor devices and materials
- Advanced Vision and Imaging
- Advanced Image and Video Retrieval Techniques
- ZnO doping and properties
- Nanopore and Nanochannel Transport Studies
- Robotics and Sensor-Based Localization
- Medical Image Segmentation Techniques
- Ga2O3 and related materials
- Advanced biosensing and bioanalysis techniques
- Ophthalmology and Eye Disorders
- Computer Graphics and Visualization Techniques
- Semiconductor Quantum Structures and Devices
- Photocathodes and Microchannel Plates
- Network Security and Intrusion Detection
- 3D Shape Modeling and Analysis
- Surgical Simulation and Training
- Advanced Malware Detection Techniques
- Image Processing Techniques and Applications
- Advanced Image Processing Techniques
- Lipid Membrane Structure and Behavior
- Advanced Steganography and Watermarking Techniques
- Quantum Information and Cryptography
- Image Retrieval and Classification Techniques
- RNA Interference and Gene Delivery
- Thin-Film Transistor Technologies
Northwest University
2021-2024
Beijing University of Chemical Technology
2024
Johns Hopkins University
2018-2023
Shanghai Ninth People's Hospital
2016-2023
Shanghai Jiao Tong University
2016-2023
Changchun University of Chinese Medicine
2023
Intuitive Surgical (United States)
2023
Beijing Normal University
2023
Shanghai CASB Biotechnology (China)
2023
National University of Defense Technology
2009-2022
High-power flip-chip light-emitting diodes (FCLEDs) suffer from low efficiencies because of poor p-type reflective ohmic contact and severe current crowding. Here, we show that it is possible to improve both the light extraction efficiency (LEE) spreading an FCLED by incorporating a highly metallic reflector made silver (Ag). The reflector, which consists Ag film covered three pairs TiW/Pt multilayers, demonstrates high reflectance 95.0% at 460 nm arbitrary angles incidence. Our numerical...
Stereo depth estimation relies on optimal correspondence matching between pixels epipolar lines in the left and right images to infer depth. In this work, we revisit problem from a sequence-to-sequence perspective replace cost volume construction with dense pixel using position information attention. This approach, named STereo TRansformer (STTR), has several advantages: It 1) relaxes limitation of fixed disparity range, 2) identifies occluded regions provides confidence estimates, 3)...
We present a self-supervised approach to training convolutional neural networks for dense depth estimation from monocular endoscopy data without priori modeling of anatomy or shading. Our method only requires endoscopic videos and multi-view stereo method, e.g., structure motion, supervise learning in sparse manner. Consequently, our neither manual labeling nor patient computed tomography (CT) scan the application phases. In cross-patient experiment using CT scans as groundtruth, proposed...
We report on the demonstration of GaN-based ultraviolet light-emitting diodes (UV LEDs) emitting at 375 nm grown patterned sapphire substrate (PSS) with in-situ low temperature GaN/AlGaN nucleation layers (NLs) and ex-situ sputtered AlN NL. The threading dislocation (TD) densities in UV LEDs GaN/AlGaN/sputtered NLs were determined by high-resolution X-ray diffraction (XRD) cross-sectional transmission electron microscopy (TEM), which revealed that TD density LED AlGaN NL was highest, whereas...
In 2015 we began a sub-challenge at the EndoVis workshop MICCAI in Munich using endoscope images of ex-vivo tissue with automatically generated annotations from robot forward kinematics and instrument CAD models. However, limited background variation simple motion rendered dataset uninformative learning about which techniques would be suitable for segmentation real surgery. 2017, same Quebec introduced robotic 10 teams participating challenge to perform binary, articulating parts type da...
Abstract The development of efficient green light-emitting diodes (LEDs) is paramount importance for the realization colour-mixing white LEDs with a high luminous efficiency. While insertion an InGaN/GaN superlattice (SL) lower In content before growth multiple quantum wells (MQWs) known to increase efficiency LEDs, actual mechanism still debated. We therefore conduct systematic study and investigate different mechanisms this system. Through cathodoluminescence Raman measurements, we clearly...
We demonstrate two types of GaN-based flip-chip light-emitting diodes (FCLEDs) with highly reflective Ag/TiW and indium-tin oxide (ITO)/distributed Bragg reflector (DBR) p-type Ohmic contacts. show that a direct contact to p-GaN layer using pure Ag is obtained when annealed at 600°C in N2 ambient. A TiW diffusion barrier covered onto used suppress the agglomeration thus maintain high reflectance during temperature annealing process. develop strip-shaped SiO2 current blocking beneath ITO/DBR...
Abstract Context T helper (Th)17 cells are correlated with many human autoimmune disorders, including Graves disease, and may play key roles in the pathogenesis of orbitopathy (GO). Objective To study phenotype Th17 patients GO healthy subjects, investigate fibrosis adipogenesis orbital fibroblasts (OFs) modulated by interleukin (IL)-17A, determine interaction between OFs. Design/Setting/Participants Blood samples tissues from controls were collected. Main Outcome Measures We conducted...
Here we demonstrate high-brightness InGaN/GaN green light emitting diodes (LEDs) with in-situ low-temperature GaN (LT-GaN) nucleation layer (NL) and ex-situ sputtered AlN NL on 4-inch patterned sapphire substrate. Compared to LEDs LT-GaN (19 nm)/sapphire template, nm)/template has better crystal quality while larger in-plane compressive strain. As a result, the external quantum efficiency (EQE) of template is lower than that due strain-induced quantum-confined Stark effect (QCSE). We show...
Image-based 2D/3D registration is a critical technique for fluoroscopic guided surgical interventions. Conventional intensity-based approa- ches suffer from limited capture range due to the presence of local minima in hand-crafted image similarity functions. In this work, we aim extend with fully differentiable deep network framework that learns approximate convex-shape function. The uses novel Projective Spatial Transformer (ProST) module has unique differentiability respect 3D pose...
Unique features of local immunity in thyroid-associated ophthalmopathy (TAO) may affect disease progression. To investigate the association between orbital immune microenvironment and TAO development. control connective tissues were collected. Single-cell sequencing examined lymphocytic infiltrates. Multicolor flow cytometry explored phenotypes different cell subsets vitro models for functional studies. Coculture experiment western blotting assay used to determine underlying mechanism...
High-quality 3D reconstructions from endoscopy video play an important role in many clinical applications, including surgical navigation where they enable direct video-CT registration. While methods exist for general multi-view reconstruction, these often fail to deliver satisfactory performance on endoscopic video. Part of the reason is that local descriptors establish pair-wise point correspondences, and thus drive struggle when confronted with texture-scarce surface anatomy....
In endoscopy, many applications (e.g., surgical navigation) would benefit from a real-time method that can simultaneously track the endoscope and reconstruct dense 3D geometry of observed anatomy monocular endoscopic video. To this end, we develop Simultaneous Localization Mapping system by combining learning-based appearance optimizable priors factor graph optimization. The are explicitly learned in an end-to-end differentiable training pipeline to master task pair-wise image alignment, one...
GaN-based ultraviolet-light-emitting diodes (UV LEDs) with 375 nm emission were grown on different-sized patterned sapphire substrates (PSSs) ex situ 15-nm-thick sputtered AlN nucleation layers by metal–organic chemical vapor deposition (MOCVD). It was observed through in optical reflectance monitoring that the transition time from a three-dimensional (3D) island to two-dimensional (2D) coalescence prolonged when GaN larger PSS, owing much longer lateral growth of GaN. The full widths at...
This present study aims to investigate the phenotype of IL-17A-producing T cells in thyroid-associated ophthalmopathy (TAO) and role IL-17A on RANTES IL-16 expression orbital fibroblasts (OFs) from TAO patients.Blood samples were obtained patients healthy controls subjected ELISA flow cytometry analysis. Primary human OFs cultured surgical wastes stimulated with presence or absence CD40L examined by qRT-PCR, ELISA, Western blotting, apoptosis assays.We reported upregulated IL-17A, IFN-γ,...
Tanshinone IIA protected against lipopolysaccharide-induced brain injury through the protective effect of blood-brain barrier and suppression oxidant stress inflammatory response.
We investigated effects of V‐pits embedded InGaN/GaN superlattices (SL) on optical and electrical properties high power green LEDs by changing the number SL period growth temperature. Surface morphology with various periods temperatures was evaluated using atomic force microscopy (AFM). It found that density size V‐pit increase decreasing temperature increasing periods. Experimental studies scanning electron (SEM) equipped cathodoluminescence (CL) indicated larger appear to be more effective...
Despite the fact that an InGaN/GaN superlattice (SL) is useful for enhancing performance of a GaN-based light-emitting diode (LED), its role in improving efficiency green LEDs remains open question. Here, we investigate influence V-pits-embedded SL on optical and electrical properties LEDs. We recorded sequence light emission multiple quantum wells (MQWs) grown 0- 24-pair by using scanning electron microscopy (SEM) combination with room temperature cathodoluminescence (CL) measurement, which...
Distributed Bragg reflectors (DBR) with metal film on the bottom have been demonstrated to further improve light output power of GaN-based light-emitting diodes (LEDs). Periods TiO2/SiO2 stacks, thickness film, and material metallic reflector were designed optimized in simulation software. The maximal bandwidth double-DBR stacks reached up 272 nm, which was 102 nm higher than a single-DBR stack. average reflectance LEDs wavelength from 380 780 is 95.09% at normal incident, much that stack...
Background: Recent studies have reported a wide spectrum of ocular surface injuries in the context autoimmune reactions Graves' orbitopathy (GO). Increased expression inflammatory mediators tears GO patients suggests that lacrimal glands could be target for immune responses. However, immunophenotype microenvironment is not known. This study aimed to elucidate pathological changes glands. Methods: In this case-control study, were surgically collected from who underwent orbital decompression...
Background: Graves' orbitopathy (GO) is a disfiguring and sight-threatening autoimmune disease. Previous studies have shown the infiltration of macrophages in GO orbital connective tissues. However, immunophenotypes their modulatory effects on fibroblasts (OFs) not been examined so far. In this study, we sought to determine pathophysiology GO. Methods: case-control tissues collected from 40 patients 20 healthy controls were immunohistochemically stained for cytokines macrophage cell surface...
The i-motif, a secondary structure of four-helix formed by cytosine-rich DNA (i-DNA) through C–C+ base pairing, is prevalent in human telomeres and promoters. This creates steric hindrance, thereby inhibiting both gene expression protein coding. conformation i-DNA intricately linked to the intracellular ionic environment. Hence, investigating its under various ion conditions holds significant importance. In this study, we explored impact cations on i-motif at single-molecule level using...