A5103271464- Ophthalmology and Eye Disorders
- Facial Trauma and Fracture Management
- Extracellular vesicles in disease
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Cancer Treatment and Pharmacology
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Magnesium Alloys: Properties and Applications
- Traumatic Ocular and Foreign Body Injuries
- MXene and MAX Phase Materials
- Colorectal Cancer Treatments and Studies
- Bone Tissue Engineering Materials
- Prostate Cancer Diagnosis and Treatment
- Aluminum Alloys Composites Properties
- Bone Metabolism and Diseases
- Surgical Sutures and Adhesives
- Tissue Engineering and Regenerative Medicine
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Wound Healing and Treatments
- Bone health and treatments
Shanghai Ninth People's Hospital
2016-2025
Shanghai Jiao Tong University
2016-2025
Affiliated Zhongshan Hospital of Dalian University
2016-2024
Shanghai Institute of Hematology
2018-2024
Ocean University of China
2023-2024
Ministry of Education of the People's Republic of China
2024
Johns Hopkins University
2021-2023
Bayer (United States)
2021-2022
Johns Hopkins Medicine
2021
Eisai (United States)
2017-2021
Various kinds of biodegradable Mg alloys have been developed in recent years due to their appropriate mechanical properties, biodegradation, and good biocompatibility. In this study, Mg–2.0Zn–xGd (x = 0.5, 1.0, 1.5, 2.0 wt %) were prepared. Hot extrusion was applied order refine the microstructure improve degradation resistance. The microstructure, vitro behavior investigated first. as-extruded Mg–2.0Zn–1.0Gd alloy exhibits excellent properties (UTS 338 MPa, YS 284 elongation 24%) low rate...
Large-sized orbital bone defects have serious consequences that destroy integrity and result in maxillofacial deformities vision loss. The treatment of is currently palliative not reparative, suggesting an urgent demand for biomaterials regenerate bones. In this study, via alloying, extrusion surface modification, we developed mechanobiologically optimized magnesium (Mg) scaffolds (Ca–P-coated Mg–Zn–Gd scaffolds, referred to as Ca–P–Mg) the orthotopic reconstruction large-sized defects. At 6...
Serum is one of the most commonly used biofluids for biomarker exploration. Some studies examine serum directly, while others focus on specific components like small extracellular vesicles (sEVs), which are lipid-bilayer encapsulated particles carrying a variety molecular cargos. However, diagnostic value sEVs versus sEVs-depleted fractions (EV-free serum) early cancer detection unclear. In study, size exclusion chromatography (SEC) employed to separate from prostate (PCa) suspects into...
ABSTRACT Extracellular vesicles (EVs) are essential for host–pathogen interactions, mediating processes such as immune modulation and pathogen survival. Pathogen‐derived EVs hold significant diagnostic potential because of their unique cargo, offering a wealth biomarkers. In this review, we first discuss the roles derived from various pathogens in interactions summarize latest advancements detection based on EVs. Then, highlight innovative strategies, including novel aggregate materials...
Inhaled gene therapy poses a unique potential of curing chronic lung diseases, which are currently managed primarily by symptomatic treatments. However, it has been challenging to achieve therapeutically relevant transfer efficacy in the due presence numerous biological delivery barriers. Here, we introduce simple approach that overcomes both extracellular and cellular barriers enhance vivo. We endowed tetra(piperazino)fullerene epoxide (TPFE)-based nanoparticles with non-adhesive surface...
Our purpose was to evaluate the association of a new biochemical recurrence (BCR) risk stratification system with PSMA-targeted PET/CT findings. <b>Methods:</b> Two prospective studies that included patients BCR were pooled. Findings on PSMA PET catalogued. Patients characterized according European Association Urology categories. Univariable and multivariable analyses performed by logistic regression. <b>Results:</b> In total, 145 (45 low-risk 100 high-risk). High-risk had higher positive...
Orbital blowout fractures are relatively rare in patients under 18 years of age, but may lead to serious complications. We conducted this retrospective study evaluate diplopia, clinical characteristics, and postoperative results cases orbital the pediatric population. Eighty-three patients, all less than old, with fractures, were divided into 3 groups by age: 0 6 7 12 13 old. The cause injury, fracture locations, diplopia grades, ocular motility restrictions, enophthalmos, reviewed from...
Background Trapdoor fracture is a special type of orbital blowout fracture. Although early surgery recommended, there still remain some patients delayed by various reasons. In this study, we analysed the clinical characteristics paediatric patients, especially those with different levels ocular motility restriction before surgery. Methods Thirty (3 to 14 years old) who underwent for trapdoor fractures between January 2008 and September 2016 were enrolled. Their demographics, causes injury...
Abstract Retinal degeneration, characterized by the progressive loss of retinal neurons, is leading cause incurable visual impairment. progenitor cells (RPCs)‐based transplantation can facilitate sight restoration, but clinical efficacy this process compromised imprecise neurogenic differentiation RPCs and undermining function transplanted surrounded severely oxidative lesions. Here, it shown that ultrathin niobium carbide (Nb 2 C) MXene enables performance enhancement for regeneration. Nb C...
No AccessJournal of UrologyInvestigative Urology1 Apr 2012Antigen Specific T-Cell Responses Against Tumor Antigens are Controlled by Regulatory T Cells in Patients With Prostate Cancer Boris Hadaschik, Yun Su, Eva Huter, Yingzi Ge, Markus Hohenfellner, and Philipp Beckhove HadaschikBoris Hadaschik Department Urology, University Hospital Heidelberg, Germany , SuYun Su Jiangsu Province Traditional Chinese Medicine, Nanjing, People's Republic China HuterEva Huter Dermatology, GeYingzi Ge...
Abstract Background Primary canaliculitis is a chronic infection of the proximal lacrimal pathway. We aimed to evaluate surgical outcomes canaliculoplasty procedure for primary associated with canalicular dilatation. Methods This study enrolled 42 patients dilatation who underwent canaliculoplasty. All were treated canaliculotomy, curettage contents and stent placement. Patients’ demographics, clinical features, follow-up evaluated. Results There 12 males 30 females mean age 66.1 ± 13.9...
Intraoperative bleeding and delayed postsurgical wound healing caused by persistent inflammation can increase the risk of tumor recurrence after surgical resection. To address these issues, Enteromorpha prolifera polysaccharide (PEP) with intrinsic potentials for hemostasis healing, is chemically modified into aldehyde-PEP hydrazine-PEP. Thereby, an injectable double-network hydrogel (OPAB) developed via forming dual dynamic bonding acylhydrazone bonds between decorated aldehyde hydrazine...
BACKGROUND:The aim of the present study was to establish normal-range orbital parameters and explore relationships between ocular protrusion various morphological factors. MATERIAL AND METHODS:A retrospective, non-comparative case series conducted from January 2014 December 2015. We recruited 56 subjects (112 orbits), including 27 males (21 87 years age) 29 females (22 88 in this study. Nine length measurements, 2 angle volume measurements aspects orbit were obtained using Mimics v18.0...