A5031193726- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Hepatitis C virus research
- Polyomavirus and related diseases
- Liver Disease and Transplantation
- Organ Donation and Transplantation
- Renal Diseases and Glomerulopathies
- Neurological Complications and Syndromes
- Cytomegalovirus and herpesvirus research
- Organ Transplantation Techniques and Outcomes
- Renal and Vascular Pathologies
- Diverticular Disease and Complications
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Drug-Induced Hepatotoxicity and Protection
- Palliative Care and End-of-Life Issues
- Health Literacy and Information Accessibility
- Hepatitis B Virus Studies
- Hernia repair and management
- Oral and gingival health research
- Erythropoietin and Anemia Treatment
- Intestinal Malrotation and Obstruction Disorders
- Testicular diseases and treatments
- Parvovirus B19 Infection Studies
- Autoimmune and Inflammatory Disorders
Allegheny General Hospital
2022-2025
Allegheny Health Network
2022-2025
The Ohio State University
2020-2024
Drexel University
2022
The Ohio State University Wexner Medical Center
2020-2021
Memphis Health Center
2019
Washington University in St. Louis
2016-2017
Beaumont Hospital, Royal Oak
2013
Neumont University
2013
Background Initial and subsequent kidney transplantation improves survival compared to continued dialysis. We initial repeat deceased-donor outcomes at different donor profile index (KDPI) levels using an adjusted mate-kidney model. Materials Methods Deceased donors whose kidneys were transplanted into adults identified from the organ procurement transplant network/united network for sharing database. Patients received peri-operative induction maintenance tacrolimus/mycophenolate. Transplant...
Humoral immune responses against donor antigens are important determinants of long-term transplant outcomes. Reactivation the polyomavirus BK has been associated with de novo antibodies mismatched HLA in kidney transplantation. The effect reactivation (BK viremia or JC viruria) on to kidney-specific self-antigens is unknown. We previously reported excellent 5-year outcomes after minimization immunosuppression for and no intervention viruria. Here, we report 10-year results this trial ( n...
Background: Cardiovascular disease is the leading cause of death in kidney transplant recipients. Physical activity after most modifiable nonpharmacological factor for improving cardiovascular outcomes. Few studies have tested walking interventions to enhance daily steps and health outcomes older Methods: Using a pilot feasibility randomized clinical trial design, we efficacy 6-month SystemCHANGE™ (Change Habits by Applying New Goals Experience) + Activity Tracker intervention recruitment,...
The success of direct-acting antivirals (DAA) has transformed the management hepatitis C virus (HCV) infection and led to expansion deceased donor organ pool for liver transplantation.We present a single center retrospective review transplantations performed on HCV-seronegative recipients from HCV-seropositive organs 11/2017 05/2020. HCV nucleic acid testing (NAT) was donors assess active infection.42 underwent transplant donor, including 21 NAT negative (20 liver, 1 simultaneous kidney...
Blood transfusion is a risk factor for allosensitization. Nevertheless, blood posttransplant remains common practice. We evaluated the effect of on graft outcomes.We included nonsensitized, first-time, kidney-alone recipients transplanted between 1 July 2015 and 31 December 2017. Patients were grouped based receiving in first 30 days posttransplant. The primary end point was composite outcome biopsy-proven acute rejection, death any cause, or failure year Secondary outcomes individual...
The management of atherosclerotic renal artery stenosis in patients with hypertension or impaired function remains a clinical dilemma. current general consensus, supported by the results Angioplasty and Stenting for Renal Atherosclerotic Lesions Cardiovascular Outcomes Artery trials, argues strongly against endovascular intervention favor optimal medical management. We discuss limitations implications contemporary trials present our approach formulate clear recommendations to help narrowing artery.
kidney transplantation from Hepatitis C virus (HCV) viremic donors to uninfected recipients is associated with excellent short-term outcomes. However, HCV viremia might be an increased risk for post-transplant viral complications.We designed a retrospective study of HCV-negative kidney-only transplant between 2018 and 2020. Recipients were grouped into group 1; donors, 2; HCV-viremic donors. Patients matched 1:1 using propensity score. The primary objectives compare the incidence...
Large sliding inguinal hernias involving the urinary bladder are rare. If left untreated, effect can be devastating, leading to infarction, perforation or obstruction. The is involved in 1–4% of all hernias.1 Review literature reveals that large scrotal cystoceles very rare, occurring …
Abstract CMV infection and Th17 cells are independently associated with increased risk for late allograft loss after renal transplantation. Although CMV-specific detectable in animal models nontransplant clinical populations, evidence linking transplantation remains unclear. This prospective observational study evaluated a cohort of transplant recipients during 12 mo posttransplant to assess the presence peripheral blood their relationship pretransplant serostatus DNAemia. were identified...
Abstract Background Weight gain after a kidney transplant remains major problem that can lead to adverse effects on morbidity and mortality. The posttransplant phase provides window of opportunity improve the engagement self-management care for lifestyle modifications diet physical activity. purpose our study was (1) test feasibility recruitment, retention, adherence using Technology, Application, Self-Management Kidney (TASK) intervention in post-kidney recipients (≥ 18 years age) at...
Ryhal, Robert; Daloul, Reem; Nashar, Khaled; Sureshkumar, Kalathil K. Author Information
A 40-year-old previously healthy woman presented with a history of painful maculopapular rash, fever and diffuse arthralgia. The skin biopsy was consistent Sweet's syndrome. Further workup abdominal CT revealed bilateral hypoenhancing renal lesions involving the cortex medulla, as well terminal ileal thickening. Her function preserved. urinalysis microscopic haematuria sterile pyuria. Upper lower gastrointestinal endoscopies were unremarkable normal. evaluation for secondary causes syndrome...
The advent of direct-acting antiviral (DAA) therapies has allowed kidney transplantation from hepatitis C (HCV)-viremic donors into negative recipients. We evaluated the safety and feasibility such practice when utilizing a patient's health plan to cover cost for DAAs.This was prospective, non-randomized, pilot clinical study. 30 HCV-negative participants received transplant HCV-viremic deceased donors. HCV polymerase chain reaction (PCR) checked on day 3 post transplant, request...
Leone, Mario A.; Daloul, Reem; Landau, Michael; Nashar, Khaled; Sureshkumar, Kalathil K.; AHN Author Information