A5031909331- Electromagnetic Fields and Biological Effects
- Magnetic and Electromagnetic Effects
- Biofield Effects and Biophysics
- Spaceflight effects on biology
- Carcinogens and Genotoxicity Assessment
- Plant Genetic and Mutation Studies
- Radiation Effects and Dosimetry
- Ultrasound and Hyperthermia Applications
- DNA Repair Mechanisms
- Neuroscience and Neural Engineering
- bioluminescence and chemiluminescence research
- Chemical Reactions and Isotopes
- Photoreceptor and optogenetics research
- Animal Vocal Communication and Behavior
- Wildlife-Road Interactions and Conservation
- Non-Invasive Vital Sign Monitoring
- Wireless Body Area Networks
- Gut microbiota and health
- Radiation Therapy and Dosimetry
- Biomedical and Engineering Education
- Virus-based gene therapy research
- Freezing and Crystallization Processes
- Effects and risks of endocrine disrupting chemicals
- Electron Spin Resonance Studies
- Genetically Modified Organisms Research
Railway Technical Research Institute
2009-2025
Centro Regional de Derechos Humanos y Justicia de Género, Corporación Humanas
2018
Keio University
2016
Jikei University School of Medicine
2011
University of Illinois Chicago
2004
Tokyo University of Agriculture and Technology
2000
The tumor suppressor protein p53 is known to induce either apoptosis or growth arrest depending on cellular background. We have previously reported that a bacterial redox azurin induces in J774 cell line-derived macrophages whereas site-directed mutant M44KM64E shows very little cytotoxicity and fails cells. now report purified can enter both cells as well the human breast cancer MCF-7 Entry of causes strong inhibition cell-cycle progression at G 1 S phase higher level transcription p21...
Abstract Electromagnetic radiation energy at millimeter wave frequencies, typically 30 GHz to 300 GHz, is ubiquitously used in society devices for telecommunications; radar and imaging systems vehicle collision avoidance, security screening, medical equipment; scientific research tools spectroscopy; industrial applications non-destructive testing precise measurement; military defense applications. Understanding the biological effects of this technology essential. We have been investigating...
To assess the possibility that strong static magnetic fields cause DNA damage and mutation, we examined genotoxic effects of field exposure by using somatic mutation recombination test system in repair-proficient -deficient strains Drosophila melanogaster. A postreplication repair-defective mei-41D5 and/or a nucleotide excision mei-9(a) was introduced into conventional loss heterozygosity assay use mwh +/ + flr transheterozygotes, were exposed to up 14 Tesla (T). We found 2, 5, or T for 24 h...
The embryotoxic effect of intermediate frequency (IF) magnetic field (MF) was evaluated using murine embryonic stem (ES) cells and fibroblast based on the cell test (EST). were exposed to 21 kHz IF-MF up flux density 3.9 mT during proliferation process (7 days) or differentiation (10 which an body differentiated into myocardial cells. As a result, there no significant difference in between sham- IF-MF-exposed for both ES Similarly, ratio number ES-derived aggregates total not changed by...
Effects of magnetic fields (MFs) on biological systems are usually investigated using indices such as gene expression profiles. However, to precisely evaluate the effects MF, intense MFs systematic material transport processes including experimental environment must be seriously taken into consideration. In this study, a culture budding yeast, Saccharomyces cerevisiae, was used model for an in vitro test system. After exposure 5 T static vertical we found difference sedimentation pattern...
Koana, T., Takashima, Y., Okada, M. O., Ikehata, M., Miyakoshi, J. and Sakai, K. A Threshold Exists in the Dose– Response Relationship for Somatic Mutation Frequency Induced by X Irradiation of Drosophila. Radiat. Res. 161, 391– 396 (2004).The dose–response relationship ionizing radiation its stochastic effects has been thought to be linear without any thresholds. The basic data this model were obtained from mutational assays male germ cells fruit fly Drosophila melanogaster. However, it is...
Indium Chloride‐induced Micronuclei in In Vivo and Vitro Experimental Systems: Ryo Takagi, et al. Department of Public Health Environmental Medicine, Jikei University School Medicine— Objectives The aim this study was to investigate the genotoxic effects indium trichloride (InCl 3 ·4H 2 O; InCl ) using vivo bone marrow micronucleus test vitro CHL/IU cell test. Method BALB/c mice were administered a single intraperitoneal (i.p.) injection at dose 0.625, 1.25, 2.5, 5, or 10 mg/kg b.w....
Deer-train collisions have become a serious problem in Japan. Deer been observed entering tracks through gaps fences or at level crossings. To keep deer away from railway lines, an acoustic deterrent was developed and tested for effectiveness. The consists of device that emits alarm calls dog calls. Field observations revealed playing back the sound towards near track made them run immediately. According to survey on frequency with which were emission train resulted 45 % reduction every 100...
Recently, induction heating systems are being widely used in many applications, and wireless power transmission introduced into commercially available electrical vehicles. These applications use time varying magnetic fields (under 100 kHz) which close proximity of the human body. Therefore, it should be discussed an influence around kHz to This paper presents design implementation a field generator for biological research. While conventional generators only produce one frequency component,...
Stimulus response of cultured neurons during high-intensity intermediate-frequency magnetic field exposure was detected by a non-conductive fibre-optic imaging system.
Abstract Purpose: To evaluate the biological effects of static magnetic fields (SMFs) up to 13 Tesla (T), with respect superoxide behavior, by determining effect on mutagenicity in dismutase (SOD)‐deficient Escherichia coli strain QC774, and its parental GC4468. Materials Methods: Experimental strains were exposed a 5, 10, or 13T SMF for 24 h at 37°C Luria‐Bertani medium. after exposure, mutation frequency thymine synthesis genes was determined. The exposure 5 induced plumbagin also...
Purpose: To assess the possibility that extremely low frequency (ELF) magnetic fields obstruct damage repair process, gene conversion and cell cycle kinetics in a DNA repair‐proficient nucleotide excision (NER)‐deficient strain of diploid yeast Saccharomyces cerevisiae.Materials methods: repair‐ or NER‐deficient cells were irradiated with sublethal doses ultraviolet light (UV) radiation followed by exposure to 50 Hz up 30 mT for 48 h. After exposure, colony‐forming ability was scored as...
Since the opportunities that people are exposed to intermediate frequency (IF) magnetic fields (MF) increasing, health risk assessment of IF-MF has now become important. Because there have been few studies about long-term exposure with high flux density, we developed a new apparatus capable up 3.9 mT for in vitro study. In this study, found out did not affect both cell growth and mutagenicity using mammalian line CHO-K1 its DNA repair deficient derivatives.