- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Mental Health Research Topics
- EEG and Brain-Computer Interfaces
- Neurobiology and Insect Physiology Research
- Tryptophan and brain disorders
- Insect Utilization and Effects
- Olfactory and Sensory Function Studies
- Advanced Neuroimaging Techniques and Applications
- Nonlinear Dynamics and Pattern Formation
- Stress Responses and Cortisol
- Metabolism, Diabetes, and Cancer
- Pain Mechanisms and Treatments
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Neuroscience and Neuropharmacology Research
- Health, Environment, Cognitive Aging
- Heart Rate Variability and Autonomic Control
- Eating Disorders and Behaviors
- Pain Management and Placebo Effect
University of Michigan
2024
Hospital for Sick Children
2024
SickKids Foundation
2024
University of Birmingham
2024
Shahid Beheshti University
2021-2022
Institute for Cognitive Science Studies
2021-2022
Institute for Research in Fundamental Sciences
2015-2016
California State University, Northridge
2001
Stability is a physical attribute that stands opposite the change. However, it still unclear how arrangement of links called topology affects network stability. In this study, we tackled issue in resting-state brain using structural balance. Structural balance theory employs quality triadic associations between signed to determine showed negative make hubs reduce balance-energy and push into more stable state compared null-networks with trivial topologies. regard, created global measure...
BackgroundChronic low-grade inflammation is observed across mental disorders and associated with difficult-to-treat-symptoms of anhedonia functional brain changes – reflecting a potential transdiagnostic dimension. Previous investigations have focused on distinct illness categories in those enduring illness, few exploring inflammatory changes. We sought to identify an signal function underlying among young people recent onset psychosis (ROP) depression (ROD).MethodResting-state magnetic...
Which properties of a molecule define its odor? This is basic yet unanswered question regarding the olfactory system. The system Drosophila has repertoire approximately 60 odorant receptors. Molecules bind to receptors with different affinities and activate them efficacies, thus providing combinatorial code that identifies odorants. We hypothesized binding affinity an odorant-receptor pair affected by their relative sizes. maximum can be attained when molecular volume matches pocket. drops...
Abstract The brain is a frustrated system that contains conflictual link arrangements named frustration. frustration as source of disorder prevents the from settling into low-energy states and provides flexibility for network organization. In this research, we tried to identify pattern formation in at levels region, connection, canonical network, hemisphere. We found has no uniform pattern. Some subcortical elements have an active role formation, despite low contributions many cortical...
Many studies have focused on neural changes and neuroplasticity, while the signaling demand for modification needs to be explored. In this study, we traced issue in organization of brain functional links where conflictual arrangement signed makes a request change. We introduced number frustrations (unsatisfied closed triadic interactions) as measure assessing "requirement change" network. revealed that requirement change resting-state network has u-shape functionality over lifespan with...
To study olfaction, first we should know which physical or chemical properties of odorant molecules determine the response olfactory receptor neurons, and then effect those on combinatorial encoding in system. In this work show that an neuron Drosophila depends molecular volume odorant; The determines upper limits neural response, while actual may depend other molecules. Each prefers a particular volume, with some degree flexibility. These two parameters predict flexibility binding-pocket...
Abstract The developing child and adolescent brain is thought to have an increased vulnerability the negative impact of obesity excessive consumption hyperpalatable energy-rich foods. In this study, we investigated neurophysiological effects overweight in 30 participants spanning childhood adolescence (8-19 years), using a naturalistic viewing paradigm with Inscapes, pseudo-resting-state protocol scan magnetoencephalography (MEG). Subjects were median split on body mass indices (BMI),...
Abstract Chronic pain is a pervasive condition that involves complex neurobiological mechanisms and frequently co-occurs with mental health challenges such as anxiety, depression, posttraumatic stress disorder (PTSD), interacting significantly psychiatric outcomes. Despite its prevalence, the neural of chronic interactions remain poorly understood – however, functional brain imaging studies suggest “pain connectome”, collection regions amongst numerous networks, plays role in mediating...
Network energy has been conceptualized based on structural balance theory in the physics of complex networks. We utilized this framework to assess functional brain networks under cognitive control and understand how is allocated across canonical during various tasks. extracted network from connectivity patterns subjects who underwent fMRI scans tasks involving working memory, inhibitory control, flexibility, addition task-free scans. found that whole-brain increases when exposed compared...
Network energy has been conceptualized based on structural balance theory in the physics of complex networks. We utilized this framework to assess functional brain networks under cognitive control and understand how is allocated across canonical during various tasks. extracted network from connectivity patterns subjects who underwent fMRI scans tasks involving working memory, inhibitory control, flexibility, addition task-free scans. found that whole-brain increases when exposed compared...
Abstract Stability is a physical attribute that stands opposite the change. However, it still unclear how arrangement of links called topology affects network stability. In this study, we tackled issue in resting-state brain using structural balance. Structural balance theory employs quality triadic associations between signed to determine showed negative make hubs reduce balance-energy and push into more stable state compared null-networks with trivial topologies. regard, created global...
We have recently shown chronic leptin administration to improve insulin-stimulated skeletal muscle glucose transport in insulin-resistant (Yaspelkis et al., AJP, press), but did not address if basal was affected. Therefore, the aim of this investigation determine non-insulin stimulated (basal) is improved response administration. Twenty-four male Sprague Dawley rats were divided into one two groups: 1) Normal diet (n = 8) or 2) High-Fat 16). (CON) animals received standard rat chow for 12...
Abstract The brain is a frustrated system that contains conflictual link arrangements named frustration. frustration as source of disorder prevents the from settling into low energy states and provides flexibility for network organization. In this research, we tried to identify pattern formation in at levels region, connection, canonical network, hemisphere. We found has not uniform pattern. Some subcortical elements have an active role formation, despite many contributed cortical elements....