- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Medical Image Segmentation Techniques
- Medical Imaging Techniques and Applications
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Advanced NMR Techniques and Applications
- Ultrasound Imaging and Elastography
- Neurological Disease Mechanisms and Treatments
- Photoacoustic and Ultrasonic Imaging
- Ultrasonics and Acoustic Wave Propagation
- Corneal Surgery and Treatments
- Cerebral Palsy and Movement Disorders
- MRI in cancer diagnosis
- NMR spectroscopy and applications
- Botulinum Toxin and Related Neurological Disorders
- ECG Monitoring and Analysis
- Dementia and Cognitive Impairment Research
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Corneal surgery and disorders
- Pharmacological Effects and Toxicity Studies
- Advanced Image Fusion Techniques
- Nephrotoxicity and Medicinal Plants
Eye & ENT Hospital of Fudan University
2019-2024
Yuhuangding Hospital
2023-2024
Jinan University
2023
AnatomyWorks (United States)
2015-2022
Johns Hopkins University
2012-2022
KU Leuven
2022
Shanghai University of Medicine and Health Sciences
2022
Jiading District Central Hospital
2022
Donghua University
2021
Capital Medical University
2021
Image analysis tools for brain magnetic resonance imaging (MRI) have become increasingly important computer-aided diagnosis that involves large amounts of medical image data. The authors this article endeavored to develop software serve the clinical research community, starting with a stand-alone executable, hybrid local computation model today's modern architecture cloud services, which they call MRICloud. MRICloud provides high-throughput neuroinformatics platform automated MRI...
Purpose The purpose of this study is to present a cloud‐based spectral simulation tool “MRSCloud,” which allows MRS users simulate vendor‐specific and sequence‐specific basis set online in convenient time‐efficient manner. This can sets for GE, Philips, Siemens MR scanners, including conventional acquisitions editing schemes with PRESS semi‐LASER localization at 3 T. Methods MRSCloud was built on the functionality FID‐A software package. We added three extensions accelerate computation (ie,...
In this paper, we propose a novel method for parcellating the human brain into 193 anatomical structures based on diffusion tensor images (DTIs). This was accomplished in setting of multi-contrast diffeomorphic likelihood fusion using multiple DTI atlases. are modeled as high dimensional fields, with each voxel exhibiting vector valued feature comprising mean diffusivity (MD), fractional anisotropy (FA), and fiber angle. For structure, probability distribution element is mixture Gaussians,...
Abstract Introduction The increasing use of large sample sizes for population and personalized medicine requires high‐throughput tools imaging processing that can handle amounts data with diverse image modalities, perform a biologically meaningful information reduction, result in comprehensive quantification. Exploring the reproducibility these reveals specific strengths weaknesses heavily influence interpretation results, contributing to transparence science. Methods We tested–retested...
The combination of neuroimaging and cognition characteristics may provide complementary information for early identification mild cognitive impairment (MCI). This study aimed to establish the clinical relevance between cerebral small vessel disease (CSVD) burden MCI further explored linked CSVD applying a propensity score matching (PSM) approach.The was designed as case-control study. All subjects underwent standard assessments, neuropsychological testing battery (including global cognition,...
Brain parcellation tools based on multiple-atlas algorithms have recently emerged as a promising method with which to accurately define brain structures. When dealing data from various sources, it is crucial that these are robust for many different imaging protocols. In this study, we tested the robustness of multiple-atlas, likelihood fusion algorithm using Alzheimer's Disease Neuroimaging Initiative (ADNI) six protocols, comprising three manufacturers and two magnetic field strengths. The...
The current synthesis routes of anthocyanins are relatively complicated, which significantly hinders their development. We optimized the method by introducing a selective iodination reaction and also established general scheme for preparing anthocyanin diglycosides. This allows to require fewer steps costs. Based on this, we prepared four common two diglucosides measured antioxidant anti-insulin resistance activities.
Purpose To analyze diffusion tensor imaging (DTI) in two types of cerebral palsy (CP): the athetotic‐type and spastic‐type, using an atlas‐based anatomical analysis entire brain, to investigate whether these images have unique characteristics that can support functional diagnoses. Materials Methods We retrospectively analyzed DTI seven children with athetotic‐type, 11 20 healthy control children, all age‐matched. The severity motor dysfunction was evaluated Gross Motor Function...
Heart conditions of human body can be detected by the electrical signal from heart which is called electrocardiogram (ECG) and rate number beat per minute (BPM). ECG result electric that caused to beat. The shown as a wave on monitor or graph paper. disease has become very big issue nowadays. Many people get sick even die because inability their properly. This serious prevented monitoring heart's condition regularly. It would great if this done remotely. In paper, such system proposed using...
Cerebrovascular Reactivity (CVR) provides an assessment of the brain’s vascular reserve and has been postulated to be a sensitive marker in cerebrovascular diseases. MRI-based CVR measurement typically employs alterations arterial carbon dioxide (CO2) level while continuously acquiring Blood-Oxygenation-Level-Dependent (BOLD) images. CO2-inhalation resting-state methods are two commonly used approaches for MRI. However, processing MRI data often requires special expertise may become obstacle...
Purpose: To investigate the correlation between anterior chamber volume (ACV) and corneal biomechanical properties in healthy primary angle closure (PAC) eyes. Methods: A total of 79 eyes from 55 participants were enrolled this study, including 24 17 PAC patients 38 normal subjects. Anterior was detected via swept-source segment optical coherence tomography (OCT), cornea data obtained visualization Scheimpflug technology (Corvis ST). student's t-test, Chi-square test, Pearson's coefficients,...
The main aim of the study was to prove compensative effect intestine for renal function. Rat kidney impaired by intragastrically administrating adenine (400 mg per day 5 days). Intestinal tract harvested and equally divided into 20 segments except cecum. Kidneys were histologically examined with hematoxylin-eosin staining kits. Uric acid, urea (BUN), creatinine in serum determined assay kits, BUN every intestinal segment also determined. results showed that able increase uric acid level from...
Most phase aberration measurement algorithms have an ambiguity for constant and tilted profiles. Based on the Fresnel (near field) approximation with single range focusing Fraunhofer (far approximation, profiles change position of focal point only do not influence image quality. Therefore, are generally considered to be harmless ignored in those related theoretical analyses. However, approximations may become invalid under many medical ultrasound imaging situations, e.g., when field is very...
A surface Dielectric Barrier Discharge (DBD) reactor was utilized to degrade phenol in water. Different power supplies applied the DBD affect discharge modes, formation of chemically active species and thus removal efficiency pollutants. It is important select an optimized supply for reactor. In this paper, influence types including alternate current (AC) bipolar pulsed on ozone generation a measured. found that compared with supply, higher energy O3 obtained when supplied 50Hz AC supply....
For patients with cognitive disorders and dementia, accurate prognosis of worsening is critical to their ability prepare for the future, in collaboration health-care providers. Despite multiple efforts apply computational brain magnetic resonance image (MRI) analysis predicting worsening, several successes, MRI not routinely quantified clinical settings guide decision-making. To encourage use a cutting-edge segmentation method, we developed prediction model as part an established web-based...
Abstract Background Accurate quantification of in vivo proton magnetic resonance spectra involves modeling with a linear combination known metabolite basis functions. Basis sets can be generated by numerical simulation using the quantum mechanical density-matrix formalism. simulations for set require correct sequence timings, and pulse shapes durations. Purpose To present cloud-based spectral tool ‘MRSCloud’. It allows community users MRS to simulate vendor- sequence-specific online...
Purpose: To examine the feasibility and potential difficulties of automatically generating radiologic reports (RRs) to articulate clinically important features brain magnetic resonance images. Materials Methods: We focused on examining atrophy by using magnetization-prepared rapid gradient-echo (MPRAGE) The technology was based multi-atlas whole-brain segmentation that identified 283 structures, from which larger superstructures were created represent anatomic units most frequently used in...
Purpose To analyze diffusion tensor imaging (DTI) in two types of cerebral palsy (CP): the athetotic‐type and spastic‐type, using an atlas‐based anatomical analysis entire brain, to investigate whether these images have unique characteristics that can support functional diagnoses. Materials Methods We retrospectively analyzed DTI seven children with athetotic‐type, 11 20 healthy control children, all age‐matched. The severity motor dysfunction was evaluated Gross Motor Function...
Purpose To compare corneal biomechanical properties and intraocular pressure (IOP) measurements in patients who underwent Descemet’s stripping with endothelial keratoplasty (DSEK) those of the follow healthy eyes. Methods In this retrospective comparative study, a total 35 eyes DSEK by single surgeon from 2015.02 to 2019.12 were enrolled along their fellow Corneal parameters assessed at least 3 months post-DSEK using Visualization Scheimpflug Technology (CST). IOP was measured CST, Goldmann...