A5101556796- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Injection Molding Process and Properties
- Nanofabrication and Lithography Techniques
- Esophageal Cancer Research and Treatment
- Material Properties and Applications
- Acne and Rosacea Treatments and Effects
- Flame retardant materials and properties
- Contact Dermatitis and Allergies
- Optical Imaging and Spectroscopy Techniques
- Skin Protection and Aging
- Biomedical and Engineering Education
- Lung Cancer Diagnosis and Treatment
- Optical Coherence Tomography Applications
- Psychology and Mental Health
- Lung Cancer Treatments and Mutations
- Cellular Mechanics and Interactions
L'Oréal (France)
2025
AstraZeneca (Portugal)
2024
University of Lisbon
2020-2023
Aalto University
2021-2023
Groupe Clarins (France)
2023
Centro Hospitalar do Porto
2013
Abstract Objective To assess, clinically and instrumentally, the efficacy of a stabilized 12% Vitamin C (VC)‐based serum (pH 6) on skin photoageing women various age phototype. Materials Methods Eighty women, with Phototypes I to VI, (45–70y) living in Mauritius, participated an open, uncontrolled study. After two‐week period washout, they applied C‐based twice day for 2 months onto their whole face as well hydrating cream every evening ensure comparable hydration level all subjects. At set...
Abstract The International Design Engineering Annual (IDEA) Challenge is a virtually hosted hackathon for researchers with aims of: i) generating open access datasets; ii) fostering community between researchers; and, iii) applying great design minds to develop solutions real problems. This paper presents the 2022 IDEA challenge and elements of captured dataset aim providing insights into prototyping behaviours at hackathons, comparing it 2021 reflections learnings from two years running...
The objective of this study was to develop a method for the preparation and characterization paroxetine (PRX) tablets, obtained by coupling hot-melt extrusion fused deposition modelling (FDM)-based three-dimensional printing (3DP) technology. impact process parameters on drug stability tablets performance assessed.Tablets were FDM extruded PRX-loaded filaments. Physicochemical, thermal, spectroscopic, diffractometric analysis in-vitro dissolution tests intermediate products finished dosage...
Knowing the evolution of skin’s response to mechanical solicitations and understanding its origin is important in medicine, surgery, cosmetics. Studies performed vitro ex vivo show that links exist between topographic skin properties collagen elastin fibers network dermis. But, our knowledge, no study shows this link. In we propose a combination experimental tests demonstrate link dermis vivo. The first method consists analyzing relief images. second uses recently developed imaging technique...
The successful integration of hot-melt extrusion (HME) and fused deposition modelling (FDM) depends on a better understanding the impact environmental conditions printability formulations, since they significantly affect properties raw materials, whose control is crucial to enable three-dimensional printing (3DP). Hence, objective this work was investigate correlation between settings paroxetine (PRX)-loaded filaments, previously produced by HME, which FDM. influence different drying methods...
Aim: Lung cancer is the most common cause of death in Portugal. The Dutch–Belgian lung screening (LCS) study (NELSON), biggest European LCS study, showed a mortality reduction high-risk population when being screened. In this cost–effectiveness LCS, based on NELSON protocol and outcomes, was evaluated compared with no Methods: present modified an established decision tree by incorporating state-transition Markov model to evaluate health-related advantages economic implications low-dose...
This work reports the preliminary development of paroxetine-containing formulations amenable to hot-melt extrusion coupled fused deposition modelling-based 3D printing. Polymeric matrices were used alone, or added with processing enhancers (e.g., plasticizer and filler). The polymeric formulation containing paroxetine (30% w/w), hydroxypropylcellulose (54% w/w) excipients (16% w/w dicalcium dihydrate phosphate, magnesium stearate triethylcitrate; 10:1:5 ratio) exhibited most suitable...
This work presents the preliminary development of paroxetine-based formulations containing hydroxypropylcellulose (HPC) polymers suitable for hot-melt extrusion coupled to fused deposition modeling (3D printing). Two grades HPC (54% w/w), KlucelTM LF and GF, were tested in a polymeric formulation paroxetine (30% w/w) adjuvants (16% w/w dicalcium dihydrate phosphate, magnesium stearate, triethylcitrate; 10:1:5 ratio). Both exhibited release almost 100% after 12 h, but drug released from was...
Cork is a natural raw material with unique properties. It characterized by its low density, elasticity, compressibility, impermeability, and also an excellent thermal acoustic insulator as well fire-retardant material, highly resistant to abrasion. Additionally, it has remarkable environmental footprint since completely biodegradable, renewable, recyclable. Therefore, this versatile composites have many different applications, including flooring, wall coverings building facades, among others...