A5101792939- Colorectal Cancer Screening and Detection
- Gastrointestinal disorders and treatments
- 3D Printing in Biomedical Research
- Liver Disease Diagnosis and Treatment
- Diverticular Disease and Complications
- Additive Manufacturing and 3D Printing Technologies
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Parkinson's Disease and Spinal Disorders
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Nanofabrication and Lithography Techniques
- Pediatric Hepatobiliary Diseases and Treatments
- Alcohol Consumption and Health Effects
- Biliary and Gastrointestinal Fistulas
- Drug Solubulity and Delivery Systems
- Analytical Chemistry and Chromatography
- Innovative Microfluidic and Catalytic Techniques Innovation
- Gastrointestinal Tumor Research and Treatment
- Microscopic Colitis
- Parasitic infections in humans and animals
- Nerve Injury and Rehabilitation
- Thyroid Cancer Diagnosis and Treatment
- Amoebic Infections and Treatments
- Inflammatory Bowel Disease
University of Lisbon
2021
Polytechnic Institute of Castelo Branco
2021
Centro Hospitalar de Lisboa Ocidental
2017-2018
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2009
Hospital Geral de Bonsucesso
1983
Abstract Background The current standard of treatment in primary biliary cholangitis (PBC) is ursodeoxycholic acid (UDCA), although a considerable proportion patients show incomplete response resulting disease progression. Objective This study aimed to assess the prevalence UDCA and determine associated patients' characteristics. Methods Patients with PBC as main diagnosis were included from national multicentric patient registry—Liver.pt. Main endpoints according Barcelona, Paris I II...
Endoscopy is routinely performed in patients with inflammatory bowel disease to evaluate severity and guide important clinical decisions. However, variability the interpretation of endoscopic findings can significantly impact patient management. Fifty-eight gastroenterologists were invited participate an online survey including pictures video recordings colonoscopies ulcerative colitis (UC) Crohn’s (CD). Participants asked rate colorectal mucosa UC using Mayo subscore (MES), neo-terminal...
<b><i>Background &amp; Aims:</i></b> Unsedated colonoscopy can be painful, poorly tolerated by patients, and associated with unsatisfactory technical performance. Previous studies report an advantage of water exchange over conventional air insufflation in reducing pain during unsedated colonoscopy. Our goal was to analyze the impact on level maximum reported patients submitted colonoscopy, compared insufflation. <b><i>Methods:</i></b> We...
The use of ultrasonography (US) as an imaging modality in medicine has spread across almost every clinical specialty. This diffusion is based on the simplicity, accessibility, portability and affordability technique producing real-time high-resolution images using non-ionising radiation. On other hand, this trend also extended to settings than healthcare, such public facilities, private houses or remote sites. tendency can be observed worldwide, from developing countries prestigious medical...
The evaluation of the processability co-amorphous mixtures is paramount importance since these systems are increasingly used to address poor solubility presented by most drugs in research and development. This work shows that olanzapine powders present higher cohesiveness than their crystalline counterpart resulted production tablets with a tensile strength slower release drug. As result, this demonstrates despite advantages mixtures, consideration should be given downstream processing...
This work reports the preliminary development of paroxetine-containing formulations amenable to hot-melt extrusion coupled fused deposition modelling-based 3D printing. Polymeric matrices were used alone, or added with processing enhancers (e.g., plasticizer and filler). The polymeric formulation containing paroxetine (30% w/w), hydroxypropylcellulose (54% w/w) excipients (16% w/w dicalcium dihydrate phosphate, magnesium stearate triethylcitrate; 10:1:5 ratio) exhibited most suitable...
Undifferentiated carcinoma with osteoclast-like cells is a rare pancreatic neoplasm unique ultrasound endoscopic features. A 59-year-old female presented 3-month history of weight loss. Abdominal computed tomography and showed large tumor heterogeneous echotexture liver metastasis. Endoscopic fine needle aspiration was used to establish the diagnosis. In this case report, we review endoscopic, clinical, pathological features type describe for first time real-time elastography contrast...
Unsedated colonoscopy can be painful, poorly tolerated by patients and associated with unsatisfactory technical performance. Previous studies report an advantage of water exchange over conventional air insufflation in reducing pain during unsedated colonoscopy. Our goal was to analyze the impact maximum level reported submitted colonoscopy, compared insufflation.
The consistency of a printer to manufacture tablets in uniform and precise fashion is an important element when considering fused deposition modelling. Blends polymer [poly(vinyl alcohol)] drug (paracetamol) different ratios were considered evaluate the mass, content, dissolution performance, thermal properties tablets. Relative standard deviations below 5%, for most study, demonstrated high uniformity between within batch batches. Overall, study confirmed ability technology reproducible way...