A5059514526- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Hepatitis B Virus Studies
- Dysphagia Assessment and Management
- Gastrointestinal disorders and treatments
- Hepatitis C virus research
- Liver Disease and Transplantation
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- Gallbladder and Bile Duct Disorders
- Agricultural and Food Sciences
- Biliary and Gastrointestinal Fistulas
- Pediatric Hepatobiliary Diseases and Treatments
- Inflammatory Bowel Disease
- Immune Cell Function and Interaction
- Business and Management Studies
- Galectins and Cancer Biology
- Glycosylation and Glycoproteins Research
- Recycling and Waste Management Techniques
- Soil Management and Crop Yield
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gastrointestinal Tumor Research and Treatment
- Liver Diseases and Immunity
Centro Hospitalar do Porto
2015-2024
Universidade do Porto
2012-2021
Hospital de Santo António
2013-2021
CUF Porto Hospital
2017-2019
Institute for Systems Engineering and Computers
2013
This Guideline is an official statement of the European Society Gastrointestinal Endoscopy (ESGE). It addresses diagnosis and management nonvariceal upper gastrointestinal hemorrhage (NVUGIH). <b>Main Recommendations</b> <b>MR1.</b> ESGE recommends immediate assessment hemodynamic status in patients who present with acute (UGIH), prompt intravascular volume replacement initially using crystalloid fluids if instability exists (strong recommendation, moderate quality evidence). <b>MR2.</b> a...
Significance Our findings demonstrate that metabolic supplementation of mucosal T cells, isolated from patients with active ulcerative colitis (UC), N -acetylglucosamine (GlcNAc) leads to the enhancement branched N-glycosylation on cell receptor, which was associated control activation and function. These results were validated in “glycoengineered” mouse models severe colitis. Overall, our open new avenues for a targeted-specific therapy inflammatory bowel disease (IBD). The therapeutic use...
Interstitial lung [ILD] disease and granulomatous [GLD] are rare respiratory disorders that have been associated with inflammatory bowel [IBD]. Clinical presentation is polymorphic aetiology unclear.This was an ECCO-CONFER project. Cases of concomitant ILD or GLD IBD, drug-induced ILD/GLD, were collected. The criteria for diagnosing based on definitions from the American Thoracic Society European Respiratory discretion reporting clinician.We identified 31 patients ILD. majority had...
Abstract Background The current standard of treatment in primary biliary cholangitis (PBC) is ursodeoxycholic acid (UDCA), although a considerable proportion patients show incomplete response resulting disease progression. Objective This study aimed to assess the prevalence UDCA and determine associated patients' characteristics. Methods Patients with PBC as main diagnosis were included from national multicentric patient registry—Liver.pt. Main endpoints according Barcelona, Paris I II...
Information about pan-genotypic treatments for hepatitis in Portugal is scarce. We aimed to evaluate the effectiveness and safety of glecaprevir plus pibrentasvir (GLE/PIB) treatment C virus (HCV) infection real-world clinical practice.
There is a clinical need to identify biomarkers able select patients who are most likely develop aggressive/complicated disease, for early selection appropriate therapy. Changes in the glycosylation profile of intestinal lymphocytic infiltrate were previously demonstrated regulate T cell activity, being associated with disease severity ulcerative colitis [UC] patients. We interrogated whether this heterogeneous expression branched N-glycans inflammatory predicts therapy response course.The...
Direct-acting antivirals (DAA) have revolutionized hepatitis C treatment, with high sustained virological response (SVR) rates reported, even in historically difficult-to-treat groups. SVR is associated a decreased risk of hepatocellular carcinoma (HCC), need for transplantation, and overall liver-related mortality. Data from real-life cohorts on the medium- to long-term outcomes patients advanced liver disease DAA-induced are still missing.To report analyze cohort disease.In this...
Background & Aims: Endoscopic sphincterotomy (ES) with stone extraction is the standard treatment for choledocholithiasis.After retrieval, balloon-occluded cholangiography generally performed to confirm bile duct clearance but can miss residual stones particularly in patients small-sized stones, a large or pneumobilia.In addition, difficult common (CBD) requiring advanced endoscopic techniques retrieval are potential risk factor choledocholithiasis recurrence.Methods: We retrospective...
The impact of SARS-CoV-2 infection on the liver and possibility chronic disease (CLD) as a risk factor for COVID-19 severity is not fully understood. Our goal was to describe clinical outcomes inpatients regarding presence abnormal tests CLD.A retrospective analysis patients with infection, hospitalized in tertiary center Portugal, performed. Studied were hospitalization length, severity, admission intensive care unit (ICU) mortality, analyzed by CLD.We included 317 mean age 70.4 years,...
Anderloni, Andrea; Fugazza, Alessandro; Auriemma, Francesco; Maia, Luís; Maselli, Roberta; Troncone, Edoardo; D'Amico, Ferdinando; Repici, Alessandro Author Information
Background: Nonvariceal upper gastrointestinal bleeding emerges as a major complication of using antiplatelet agents and/ or anticoagulants and represents clinical challenge in patients undergoing these therapies.Aim: To characterize with nonvariceal related to antithrombotics their management, determine predictors adverse outcomes.Methods: Retrospective cohort adults who underwent endoscopy after from 2010 2012.The outcomes were compared between exposed not antithrombotics.Results: Five...
Persons with haemophilia (PWH) used to represent a population high prevalence of hepatitis C virus (HCV) infection due the use contaminated blood products. Although goals antiviral therapy are same as general population, long real-life follow-up data regarding their outcomes still scarce. Our aim was report HCV and results in PWH.A retrospective analysis performed single-centre cohort PWH positive antibody. Outcomes registered were rate spontaneous clearance HCV, sustained virologic response...
A 54-year-old man with laryngeal carcinoma treated laryngectomy and adjuvant chemoradiotherapy was referred for management of a long complete post-radiotherapy cervical esophageal obstruction. Previously, he had undergone successive endoscopic dilatations at another institution; due to loss follow-up, now presenting total aphagia.
Granulomatous (GL) and interstitial lung disease (ILD) are rare respiratory disorders that have been associated with inflammatory bowel (IBD). Clinical presentation is polymorphic aetiology unclear. This was European Crohn’s colitis organisation (ECCO) retrospective observational study performed as part of CONFER project. A call to all ECCO members made report concomitant granulomatous or ILD IBD cases. data were recorded in a standardised case form. Twenty-two patients identified from 18...
Objetivo: Descrever a distribuição da cobertura e meta vacinal Anti-Covid-19 nos municípios que compõem região metropolitana de Belém-PA. Métodos: Estudo observacional, ecológico, com dados obtidos um formulário eletrônico disponibilizado pela Secretária Saúde do Estado Pará (SESPA) Rede Dados Nacional (RNDS). Resultados: Pfizer foi vacina mais aplicada, as doses distribuídas foram bem maiores aplicadas, isso aplicadas não conseguiram alcançar estimativa populacional vacinados na Região...
Background. Most countries lack a well-coordinated approach to out-of-hours endoscopy. Economic constraints and of resources have been identified as important barriers. Objective.To assess the performance evaluation an emergency endoscopy model care. Design. During 3 year period (January 2010 December 2012), data from consecutive outpatients (n = 332) with non-variceal acute upper gastrointestinal bleeding admitted or transferred single referral hospital were prospectively collected....