A5049271769- Orbital Angular Momentum in Optics
- Advanced Fluorescence Microscopy Techniques
- Mechanical and Optical Resonators
- Digital Holography and Microscopy
- Microfluidic and Bio-sensing Technologies
- Photonic and Optical Devices
- Force Microscopy Techniques and Applications
- Quantum Information and Cryptography
- Neural dynamics and brain function
- Congenital heart defects research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Genetics and Neurodevelopmental Disorders
- Complex Network Analysis Techniques
- Opinion Dynamics and Social Influence
- Advanced Electron Microscopy Techniques and Applications
- Cold Atom Physics and Bose-Einstein Condensates
- Optical Coherence Tomography Applications
- Cell Image Analysis Techniques
- COVID-19 epidemiological studies
- Photoreceptor and optogenetics research
- Zebrafish Biomedical Research Applications
- Advanced Fiber Laser Technologies
- Gold and Silver Nanoparticles Synthesis and Applications
- Near-Field Optical Microscopy
- Composting and Vermicomposting Techniques
The University of Queensland
2014-2024
University of the West Indies
2024
University of Otago
2009-2024
Stanford Medicine
2024
Ministry for Primary Industries
2021-2023
Southern Methodist University
2017-2022
Research Institute of Molecular Pathology
2014-2018
ARC Centre of Excellence for Engineered Quantum Systems
2012-2015
Max Perutz Labs
2014-2015
University of Vienna
2014-2015
Rats use active, rhythmic movements of their whiskers to acquire tactile information about three-dimensional object features. There are no receptors along the length whisker; therefore all must be mechanically transduced back at whisker base. This raises question: how might rat determine radial contact position an whisker? We developed two complementary biomechanical models that show could distance by monitoring rate change moment (or equivalently, curvature) The first model is used explore...
Abstract Background Loss or disrupted expression of the FMR1 gene causes fragile X syndrome (FXS), most common monogenetic form autism in humans. Although disruptions sensory processing are core traits FXS and autism, neural underpinnings these phenotypes poorly understood. Using calcium imaging to record from entire brain at cellular resolution, we investigated neuronal responses visual auditory stimuli larval zebrafish, using fmr1 mutants model FXS. The purpose this study was alterations...
Abstract Habituation is a form of learning during which animals stop responding to repetitive stimuli, and deficits in habituation are characteristic several psychiatric disorders. Due technical challenges, the brain-wide networks mediating poorly understood. Here we report calcium imaging larval zebrafish repeated visual looming stimuli. We show that different functional categories loom-sensitive neurons located locations throughout brain, both properties their resulting behavior can be...
We report both sub-diffraction-limited quantum metrology and enhanced spatial resolution for the first time in a biological context. Nanoparticles are tracked with correlated light as they diffuse through an extended region of living cell photonic force microscope. This allows structure within to be mapped at length scales down 10 nm. Control experiments water show 14% enhancement compared coherent light. Our results confirm longstanding prediction that can enhance nanoscale biology....
In this paper we present a model describing susceptible-infected-susceptible-type epidemics spreading on dynamic contact network with random link activation and deletion where can be locally constrained. We use adapt an improved effective degree compartmental modeling framework recently proposed by Lindquist et al. [J. Math Biol. 62, 143 (2010)] Marceau [Phys. Rev. E 82, 036116 (2010)]. The resulting set of ordinary differential equations (ODEs) is solved numerically, results are compared to...
A major challenge in neuroscience is to sample large-scale neuronal activity at high speed and resolution. While calcium (Ca2+) imaging allows high-resolution optical read-out of activity, it remains challenging speed, as most available microscopes provide a trade-off between the size acquisition volume. One promising method that avoids rate volume light-field microscopy which full 3D profile an object imaged simultaneously, thereby offering cost reduced spatial Here we introduce speckle...
Light-sheet microscopy is used extensively in developmental biology and neuroscience. One limitation of this approach that absorption scattering produces shadows the illuminating light sheet, resulting stripe artifacts. Here, we introduce diffuse light-sheet microscopes use a line diffuser to randomize propagation within image plane, allowing sheets reform after obstacles. We incorporate two existing configurations: selective plane illumination which sample illuminated with static sheet...
Information about water flow, detected by lateral line organs, is critical to the behavior and survival of fish amphibians. While certain aspects flow processing have been revealed through electrophysiology, we lack a comprehensive description neurons that respond network they form. Here, use brain-wide calcium imaging in combination with microfluidic stimulation map out, at cellular resolution, neuronal responses involved perceiving information larval zebrafish. We find diverse array...
Abstract Hearing is a crucial sense in underwater environments for communication, hunting, attracting mates, and detecting predators. However, the tools currently used to study hearing are limited, as they cannot controllably stimulate specific parts of auditory system. To date, contributions organs have been identified through lesion experiments that inactivate an organ, making it difficult gauge stimuli which each organ sensitive, or ways inputs from multiple combined during perception....
In New Zealand, the introduced honey bee (Apis mellifera) is a valuable production animal, providing pollination services for horticultural crops and significant export volumes of honey, especially mānuka honey. Honey bees in Zealand are free from number diseases pests such as European foulbrood, acarine disease, small hive beetle, Israeli acute paralysis virus tropilaelaps mites. We sought to determine health status using longitudinal study that followed 60 beekeepers over 2.5 years,...
We present a laser amplitude modulation technique to actively stabilize the critical coupling of microresonator by controlling evanescent gap from an optical fiber taper. It is form nulled lock-in detection, which decouples intensity fluctuations measurement. achieved stabilization bandwidth ∼ 20 Hz, with up 5 orders magnitude displacement noise suppression at 10 mHz, and inferred stability better than picometer/√Hz.