A5008897918- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Thyroid Cancer Diagnosis and Treatment
- Obesity, Physical Activity, Diet
- Tissue Engineering and Regenerative Medicine
- Pancreatitis Pathology and Treatment
- Thyroid Disorders and Treatments
- Heart rate and cardiovascular health
- Phagocytosis and Immune Regulation
- Electrospun Nanofibers in Biomedical Applications
- Cardiac Structural Anomalies and Repair
- Ion channel regulation and function
- Apelin-related biomedical research
- Bipolar Disorder and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Signaling Pathways in Disease
- Body Composition Measurement Techniques
- Autophagy in Disease and Therapy
- Extracellular vesicles in disease
- Nutrition and Health in Aging
- ECG Monitoring and Analysis
- Cardiac Fibrosis and Remodeling
- Peptidase Inhibition and Analysis
Aerospace Center Hospital
2025
Peking University
2025
Shanghai Tenth People's Hospital
2020-2024
Tongji University
2020-2024
Shanghai East Hospital
2022
Tengzhou Central People's Hospital
2018
Myocardial infarction (MI) elicits cardiac fibroblast activation and extracellular matrix (ECM) deposition to maintain the structural integrity of heart. Recent studies demonstrate that Fap (fibroblast protein)-a prolyl-specific serine protease-is an important marker activated fibroblasts after MI.Left ventricle plasma samples from patients healthy donors were used analyze expression level FAP its prognostic value. Echocardiography histological analysis heart sections functions, scar...
Abstract Background Growth arrest-specific 6 (GAS6) is a vitamin K-dependent protein related to inflammation, fibrosis, as well platelet function. Genetic ablation of GAS6 in mice protects against cardiac hypertrophy and dysfunction. Nonetheless, the association between plasma levels acute heart failure (AHF) patients still unknown. Methods We measured concentrations 1039 with AHF who were enrolled DRAGON-HF trial (NCT03727828). Mean follow-up study was 889 days. The primary endpoint...
Abstract Aims Elevated heart rate (HR) in failure (HF) is associated with worse outcomes, particularly acute HF (AHF). HR reduction ivabradine reduces cardiovascular events patients reduced ejection fraction. The present trial aimed to test the hypothesis that early using improves clinical outcomes AHF. Methods and results SHIFT‐AHF a prospective, multi‐centre, double‐blind, randomized, placebo‐controlled evaluate efficacy safety of when adding standard therapy AHF (SHIFT‐AHF). will include...
Abstract Background Little is known about the predictive value of soluble AXL (sAXL) in heart failure (HF). This study aimed to describe prognostic plasma sAXL patients with symptomatic HF. Methods a multicentre observational prospective cohort (Registration No. NCT03727828). Plasma were measured on admission. The primary endpoint composite cardiovascular mortality and HF rehospitalization. Associations between levels clinical endpoints are described using Cox regression models Kaplan–Meier...
The common reason behind the development of thyrotoxic heart disease is toxic diffuse goiter via hyperthyroidism.The effect cardiovascular complexities and quality life related to health in Chinese patients with secondary has been evaluated.During July 2013-June 2015 were diagnosed goiter.Clinical assessment was performed at baseline after restoration euthyroid state follow-up.A questionnaire created used study them.Cohort data for 73 obtained.However, around half (35) these agreed...
Abstract Background: Human induced pluripotent stem cell–derived endothelial cells (hiPSC-ECs) exhibit potential in repairing the injured heart after myocardial infarction (MI) by promoting neovascularization and cardiomyocyte survival. However, because of low cellular retention poor engraftment efficacy, cell therapy treatment MI is part mediated exosomes secreted from transplanted cells. We investigated whether hiPSC-ECs could become a promising acellular approach to infarcted MI,...
Abstract Background: Growth arrest-specific 6 (GAS6) is a biomarker related to inflammation, fibrosis, as well platelet function. Knockout of GAS6 in mice subjected pressure overloading protects against cardiac hypertrophy and dysfunction. Nonetheless, the association between plasma levels acute heart failure (AHF) patients still unknown. Methods: We measured concentrations 1039 with AHF who were enrolled DRAGON-HF trial. followed them examine future clinical events. Results: In total, there...