A5018781104- Multiple and Secondary Primary Cancers
- Global Cancer Incidence and Screening
- Genetic factors in colorectal cancer
- Acute Lymphoblastic Leukemia research
- Colorectal Cancer Screening and Detection
- Childhood Cancer Survivors' Quality of Life
- Neuroendocrine Tumor Research Advances
- Lymphoma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Breast Cancer Treatment Studies
- Cancer, Lipids, and Metabolism
- Education, Psychology, and Social Research
- Urinary and Genital Oncology Studies
- Cancer Risks and Factors
- Nutrition, Genetics, and Disease
- Metabolism, Diabetes, and Cancer
- Bladder and Urothelial Cancer Treatments
- Pancreatitis Pathology and Treatment
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
Institute of Health Information and Statistics
2020-2023
Masaryk University
2020-2023
Charles University
2021
Thomayer University Hospital
2021
O2 Czech Republic (Czechia)
2021
Abstract The prevalence of second primary malignancies (SPMs) in the western world is continually increasing with risk a new cancer patients previously diagnosed carcinoma at about 20%. aim this retrospective analysis to identify SPMs colorectal single-institution cohort, describe most frequent patients, and discover time period occurrence tumors. We identified 1174 2003–2013, follow-up till 31.12.2018, median 10.1 years, (median age 63 724 men). A neoplasm was 234 (19.9%). Older those...
The aim of this study was to compare trends in mortality and incidence, clinicopathological features survival patients diagnosed with pancreatic ductal adenocarcinoma under 50 years age (early-onset cancer [EOPC]) over (late-onset [LOPC]).The national oncological registry the Czech Republic reviewed identify all histologically confirmed between 1985 2015. Incidence, mortality, data were analyzed compared EOPC LOPC.From a total 18 888 included study, 1324 (7.0%). average annual percentage...
Introduction All colorectal cancer (CRC) survivors have an increased risk of developing second primary malignancies (SPMs). The association between diabetes mellitus (DM) and the is well known. However, role DM its therapy in development SPMs CRC patients not described. Methods In this single-institutional retrospective analysis we identified 1,174 carcinoma patients, median follow-up 10.1 years, (median age 63 724 men). over 18 years with histologically confirmed who were admitted period...
Calcium channel blockers are among the most commonly used agents in treatment of cardiovascular diseases. There several known side-effects associated with their long-term use, whereas other potential adverse effects yet to be proven. This study aims evaluate association between calcium exposure and incidence second primary malignancy. We established a cohort 1401 patients colorectal cancer diagnosed our institution January 2003 December 2016. Patients were followed-up until 2020. The tumor...
Our study aimed to evaluate incidence and mortality trends for childhood adolescent cancers in the period 1994-2016 Czech Republic.Data on cancers, which are recorded National Cancer Registry, were validated using a clinical database of cancer patients combined with data from Register Hospitalised Patients death certificates. These used establish incidence. Data certificates long-term mortality. Incidence assessed by average annual percentage change.The age-standardised trend (i.e. those...
An increasing number of studies has brought evidence the protective role statin use against different types cancer. However, data on their association with second primary malignancies (SPMs) are lacking. The purpose this study was to determine hypolipidemic treatment in prevention cancer colorectal (CRC) survivors. We conducted a retrospective single-institution 1401 patients newly diagnosed from January 2003 December 2016, follow-up until 2020. SPM detected 301 (21%), and incidence...
Abstract Background Coverage by examinations is a crucial indicator of the future impact on burden colorectal cancer (CRC). The study aimed to evaluate coverage associated with CRC screening and early detection in Czech Republic. was also assessed. Methods novel nationwide administrative registry individual data (period 2010–19) used for faecal occult blood test colonoscopy. In second step, additional were included calculation (complete coverage). Age-specific trends incidence 1977–2018)...
Zhoubné novotvary prsu jsou nejčastějším onkologickým onemocněním u žen kromě nemelanomových kožních novotvarů a představují tak značnou zdravotní zátěž české populace.Cílem této práce bylo komplexně popsat epidemiologickou situaci v České republice s ohledem na dopad organizovaného mamografického screeningu.Výsledky z provedené analýzy ukázaly, že největší efekt screeningu je patrný pro věkovou skupinu 45-69 let.Po zavedení došlo věkové skupině ke stabilizaci incidence významnému poklesu...
The knowledge of cancer burden in the population, its time trends, and possibility international comparison is an important starting point for programs. A reliable interactive tool describing epidemiology children adolescents has been nonexistent Czech Republic until recently.The goal this study to develop a new web portal entitled Childhood Cancer Information System (CCCIS), which would provide information on childhood Republic.Data cancers have obtained from National Registry. These data...
Bladder neoplasms represent a significant disease burden in the Czech population. This study aimed to perform complex time trend analysis of incidence, mortality, and survival 76,505 patients with bladder based on National Cancer Registry for 1977-2017.The trends incidence mortality were evaluated using joinpoint regression. The relative Cox proportional hazards model used analysis.After 2004, annual decrease by 1.9% malignant tumors (C67) was observed, accompanied sharp increase situ cancer...
<sec> <title>BACKGROUND</title> The knowledge of cancer burden in the population, its time trends, and possibility international comparison is an important starting point for programs. A reliable interactive tool describing epidemiology children adolescents has been nonexistent Czech Republic until recently. </sec> <title>OBJECTIVE</title> goal this study to develop a new web portal entitled Childhood Cancer Information System (CCCIS), which would provide information on childhood Republic....