A5011537770- Rabies epidemiology and control
- Viral Infections and Vectors
- Virology and Viral Diseases
- Bat Biology and Ecology Studies
- SARS-CoV-2 and COVID-19 Research
- Zoonotic diseases and public health
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 detection and testing
- Yersinia bacterium, plague, ectoparasites research
Robert Koch Institute
2021-2024
The reliable detection of SARS-CoV-2 has become one the most important contributions to COVID-19 crisis management. With publication first sequences SARS-CoV-2, several diagnostic PCR assays have been developed and published. In addition in-house market was flooded with numerous commercially available ready-to-use kits, both approaches showing alarming shortages in reagent supply.
Coronaviruses (CoV) are divided into the genera α-CoVs, β-CoVs, γ-CoVs and δ-CoVs. Of these, α-CoVs β-CoVs solely capable of causing infections in humans, resulting mild to severe respiratory symptoms. Bats have been identified as natural reservoir hosts for CoVs belonging these two genera. Consequently, research on bat populations, CoV prevalence bats genetic characterization is special interest investigate potential transmission risks. We present genome sequence a novel α-CoV strain...
Bats are known to be potential reservoirs of numerous human-pathogenic viruses. They have been identified as natural hosts for coronaviruses, causing Severe Acute Respiratory Syndrome (SARS) in humans. Since the emergence SARS-CoV-2 2019 interest prevalence coronaviruses bats was newly raised. In this study we investigated different bat species living a sympatric colony Wavul Galge cave (Koslanda, Sri Lanka). three field sessions (in 2018 and 2019), 395 were captured (Miniopterus, Rousettus,...
Bats are known as typical reservoirs for a number of viruses, including viruses the family Paramyxoviridae. Representatives subfamily Orthoparamyxovirinae distributed worldwide and can cause mild to fatal diseases when infecting humans. The research on Paramyxoviruses (PMVs) from different bat hosts all over world aims understand diversity, evolution distribution these assess their zoonotic potential. A high yet unclassified PMVs bats recorded. In our study, we investigated species families...
This is the first report on molecular identification and phylogeny of Rousettus leschenaultii Desmarest, 1810, Rhinolophus rouxii Temminck, 1835, Hipposideros speoris Schneider, 1800, lankadiva Kelaart, 1850, Miniopterus fuliginosus Kuhl, 1817, bat species in Sri Lanka, inferred from analyses by mitochondrially encoded cytochrome b gene sequences. Recent research has indicated that bats show enormous cryptic genetic diversity. Moreover, even within same species, acoustic properties...
Abstract Nipah virus is an emerging pathogen with high public health relevance, causing outbreaks in South- and Southeast Asia case fatality rates. The natural reservoir host are fruit bats ( Pteropus spp ). In this study, we confirmed the presence of for first time Sri Lanka proving genetic relatedness to strains from southern India, 2007, 2018, 2019 2023. It noteworthy that shedding Virus may have a temporal variation correlates breeding season medius . Furthermore, preventive measures...
Background Leptospirosis is a bacterial infection caused by spirochetes of the genus Leptospira . It affects both humans and animals, posing significant public health threat worldwide. In Sri Lanka, leptospirosis causes annual outbreaks, particularly during monsoon seasons. The disease often difficult to diagnose can have high mortality rate. Bats are potential reservoirs for in other countries. This study investigated presence diversity bats inhabiting Wavulgalge, natural cave Lanka....
Abstract Bats are important contributors to the global ecosystems; at same time, they known be a natural reservoir host for number of human pathogenic viruses. These and many other unique features make them an interdisciplinary research object in context One Health, comprising zoology, ecology, virology, microbiology, molecular biology, immunology public health issues. Performing field studies bat often aims cover several these topics requires combination specific expertise different fields....
Bats are described as the natural reservoir host for a wide range of viruses. Although an increasing number bat-associated, potentially human pathogenic viruses were discovered in past, full picture bat viromes is not explored yet. In this study, virome composition Miniopterus phillipsi bats (formerly known fuliginosus Sri Lanka) inhabiting Wavul Galge cave, Lanka, was analyzed. To assess different possible excretion routes, oral swabs, feces and urine collected analyzed individually by...
Abstract Bats are described as the natural reservoir host for a wide range of viruses. Although an increasing number bat-associated, potentially human pathogenic viruses were discovered in past, full picture bat viromes is not explored yet. In this study, virome composition from Miniopterus fuliginosus bats inhabiting Wavul Galge cave, Sri Lanka, was analyzed. To assess different possible shedding routes, oral swabs, feces and urine collected analyzed individually by using metagenomic NGS....
Abstract This is the first report on molecular identification and phylogeny of Rousettus leschenaultii, Rhinolophus rouxii, Hipposideros speoris, lankadiva, Miniopterus fuliginosus bat species in Sri Lanka, inferred from mitochondrially encoded cytochrome b gene sequences. Wellawaya Wavulgalge cave Lanka one largest sympatric colonies found island, occupied by five bats. Recent research has indicated that bats show enormous cryptic genetic diversity. Moreover, even same species, acoustic...