A5015065013- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Medical Imaging Techniques and Applications
- Effects of Radiation Exposure
- Breast Cancer Treatment Studies
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Lung Cancer Treatments and Mutations
- Oral health in cancer treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal cell carcinoma treatment
- Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Advances in Oncology and Radiotherapy
- Anatomy and Medical Technology
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Esophageal Cancer Research and Treatment
- Brain Metastases and Treatment
- Pancreatitis Pathology and Treatment
Hoag Memorial Hospital Presbyterian
2021-2023
Alaska Native Tribal Health Consortium
2022
Albany Medical Center Hospital
2022
Methodist Hospital
2021
George Washington University Hospital
2021
Alaska Native Medical Center
2021
Swedish Medical Center
2002-2020
Seattle University
1995-2020
Polyclinic Medical Center
2020
The University of Texas MD Anderson Cancer Center
2007-2019
Helical tomotherapy (HT) and volumetric modulated arc therapy (VMAT) are arc-based approaches to IMRT delivery. The objective of this study is compare VMAT both HT fixed field in terms plan quality, delivery efficiency, accuracy.Eighteen cases including six prostate, head-and-neck, lung were selected for study. plans developed using direct machine parameter optimization the Pinnacle3 treatment planning system. a Hi-Art II station. generated SmartArc module home-grown sequencing algorithm....
Virtual reality (VR) allows for presurgical planning. Intraoperatively, augmented (AR) enables integration of segmented anatomic information with neuronavigation into the microsurgical scene to provide guidance without workflow disruption. Combining VR and AR solutions may help guide technique improve safety, efficiency, ergonomics.To describe a VR/AR platform that provides planning intraoperative via microscope ocular injection comprehensive overlay patient-specific 360°/3D model aligned...
Antibiotic utilization plays a vital role in healthcare by ensuring effective bacterial infection management while mitigating resistance risks. This study aims to examine the pattern of antibiotic respiratory and nephrological disease. A prospective cohort observational was conducted over six months nephrology wards, involving 200 patients, following approval from Institutional Ethics Committee GCS Medical College & Research Centre. Patients aged 18 years or older with diagnosed...
Introduction:The specific aims of the study were to evaluate 2-year overall survival (OS) and progression-free (PFS), toxicity profile, best objective response rate in patients with locally advanced, clinically unresectable esophageal cancer receiving cetuximab, cisplatin, irinotecan, thoracic radiotherapy (TRT) within a multi-institutional cooperative-group setting.Methods:Eligible (cT4 M0 or medically unresectable, biopsy proven, noncervical cancer) receive four 21-day cycles cetuximab 400...
Abstract: Postmastectomy chest wall and nodal radiation therapy decreases local recurrence improves disease-free overall survival. Immediate transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction after mastectomy has become more common. We report on our experience of irradiating the regional lymph nodes a TRAM describe acute side effects, viability, cosmetic outcome. Between 1995 2000, 22 patients with median age 47 years (range 27–61 years) received radiotherapy...
Mehta VK, Hao W, Brooks-Worrell BM, Palmer JP. Low-dose interleukin 1 and tumor necrosis factor individually stimulate insulin release but in combination cause suppression. Eur J Endocrinol 1994;130:208–14. ISSN 0804–4643 The macrophage-derived cytokines (IL-1) (TNF) have direct effects on pancreatic beta cells been hypothesized to play important roles the autoimmune cell lesion of type I diabetes because two major cells: altered secretion cytotoxicity. High doses IL-1 are cytotoxic strongly...
BACKGROUND: A prospective study was undertaken to evaluate the response and toxicity of neoadjuvant chemoradiotherapy for ultrasound-staged T3 or T4 rectal cancer. PATIENTS AND METHODS: Since 1995, 30 patients (18 males; median age, 56 (range, 25-83) years) have received preoperative All underwent an endorectal ultrasound, CT scan, review in our multidisciplinary Gastrointestinal Tumor Board before treatment. had pathology-demonstrated invasive adenocarcinoma rectum. Eleven were Stage T3N0,...
Hypotheses: Adjuvant chemoradiotherapy decreases the risk of local recurrence in patients with adenocarcinoma ampulla Vater and high-risk features.Adjuvant for this population can be administered safely without much morbidity.
Epidermal growth factor receptor (EGFR) is often overexpressed in tumors and has been associated with poor prognosis some cancer types. The introduction of inhibitors EGFR, such as erlotinib, represents an important recent advance the targeted treatment cancer. Several studies have evaluated EGFR combination radiotherapy, a strong biologic rationale exists for use this certain types, including head neck squamous cell carcinoma, non-small lung cancer, glioblastoma, esophageal pancreatic...
Radiation therapy (RT) with concurrent 5-fluorouracil (5-FU) administered by protracted venous infusion (PVI) replaced our prior institutional protocol of RT bolus administration 5-FU as standard for unresectable pancreatic cancer in 1994. In this article, we compare the treatment intensity, toxicity, and outcome patients treated on these sequential protocols. Fifty-four patients, 27 each protocol, biopsy-confirmed received chemoradiotherapy. The radiotherapy field included gross tumor...
The incidence of optic neuropathy after stereotactic radiosurgery (SRS) is related to the total dose, fraction size, and treatment volume. Theoretically, fractionated SRS can decrease this risk. In paper, we report our technique for assess its potential role in management tumors located adjacent anterior visual pathways. Since 1997, thirteen patients (median age: 50, range 21-76) with lesions close proximity pathways were treated on CyberKnife image guided system (Accuray, Inc., Sunnyvale,...
In this study, we have characterized the efficiency of an Elekta linac in delivery gated radiotherapy. We explored techniques to reduce beam‐on delay and improve efficiency, investigated impact frequent beam interruptions on dosimetric accuracy deliveries. A newly available gating interface was installed Synergy. Gating signals were generated using a surface mapping system conjunction with respiratory motion phantom. series deliveries performed volumetric modulated arc therapy (VMAT)...
The Preventable Shunt Revision Rate (PSRR) was recently introduced as a novel quality metric.To evaluate the PSRR across multiple centers and determine associated variables.Nine participating in North America provided at least 2 years of consecutive shunt operations. Index surgery defined new implantation, or revision an existing shunt. For any index that resulted reoperation within 90-days, information (demographic, clinical, procedural) collected decision made whether failure potentially...
To evaluate 2 published normal tissue complication probability models for radiation-induced hypothyroidism (RHT) on a large cohort of oropharyngeal carcinoma (OPC) patients who were treated with intensity-modulated radiation therapy (IMRT).OPC retrievable IMRT Digital Imaging and Communications in Medicine (DICOMs) data available baseline follow-up thyroid function tests included. Mean dose (Dmean) to the gland (TG) its volume calculated. The study outcome was clinical HT at least 6 months...
Objectives: Phase IV study evaluated the safety and device performance of an electronic brachytherapy system (Axxent Electronic Brachytherapy System) as adjuvant therapy for early-stage breast cancer. Methods: Patients were ≥50 years age had completely resected invasive ductal carcinoma or in situ (<2.0 cm), with N0 M0 negative microscopic margins ≥1 mm. The balloon applicator was placed a closed cavity surface to skin distance ≥7 prescribed dose 3.4 Gy/fraction 1 cm beyond twice daily (BID)...