Françoise Alfama

ORCID: 0000-0003-4448-306X
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About
Contact & Profiles
Research Areas
  • Wheat and Barley Genetics and Pathology
  • Plant Disease Resistance and Genetics
  • Chromosomal and Genetic Variations
  • Genetic Mapping and Diversity in Plants and Animals
  • Genomics and Phylogenetic Studies
  • Plant Pathogens and Fungal Diseases
  • Fungal Biology and Applications
  • Plant Virus Research Studies
  • Legume Nitrogen Fixing Symbiosis
  • Plant nutrient uptake and metabolism
  • Fermentation and Sensory Analysis
  • Mycorrhizal Fungi and Plant Interactions
  • Advanced Computational Techniques and Applications
  • Fungal Plant Pathogen Control
  • Digital Games and Media
  • Microbial Metabolic Engineering and Bioproduction
  • Genetics, Bioinformatics, and Biomedical Research
  • Horticultural and Viticultural Research
  • Banana Cultivation and Research
  • Plant and fungal interactions
  • Environmental Monitoring and Data Management

Centre Hospitalier de Versailles
2014-2019

Université Paris-Saclay
2017-2019

Institut National de la Recherche Agronomique
2014

Klaus Mayer Jane Rogers Jaroslav Doležel Curtis Pozniak Kellye Eversole and 91 more Catherine Feuillet Bikram Gill Bernd Friebe Adam J. Lukaszewski Pierre Sourdille Takashi R. Endo Marie Kubaláková Jarmila Číhalíková Zdeňka Dubská Jan Vrána Romana Šperková Hana Šimková Melanie Febrer Leah Clissold Kirsten McLay Kuldeep Singh Parveen Chhuneja Nagendra Kumar Singh Jitendra P. Khurana Eduard Akhunov Frédéric Choulet Adriana Alberti Valérie Barbe Patrick Wincker Hiroyuki Kanamori Fuminori Kobayashi Takeshi Itoh Takashi Matsumoto Hiroaki Sakai Tsuyoshi Tanaka Jian Wu Yasunari Ogihara Hirokazu Handa P. Ron Maclachlan Andrew Sharpe Darrin Klassen David Edwards Jacqueline Batley Odd-Arne Olsen Simen R. Sandve Sigbjørn Lien Burkhard Steuernagel Brande B. H. Wulff Mario Cáccamo Sarah Ayling Ricardo H. Ramírez-González Bernardo Clavijo Jonathan Wright Matthias Pfeifer M. Spannagl Mihaela M. Martis Martin Mascher Jarrod Chapman Jesse Poland Uwe Scholz Kerrie Barry Robbie Waugh Daniel S. Rokhsar Gary J. Muehlbauer Nils Stein Heidrun Gundlach Matthias Zytnicki Véronique Jamilloux Hadi Quesneville Thomas Wicker Primetta Faccioli Moreno Colaiacovo A. M. Stanca Hikmet Budak Luigi Cattivelli Natasha Glover Lise Pingault Etienne Paux Sapna Sharma R. Appels M. Bellgard Brendan Chapman Thomas Nußbaumer Kai Christian Bader Hélène Rimbert Shichen Wang R. E. Knox Andrzej Kilian Michaël Alaux Françoise Alfama L.J. Couderc Nicolas Guilhot Claire Viseux Mikaël Loaec Beat Keller Sébastien Praud

An ordered draft sequence of the 17-gigabase hexaploid bread wheat (Triticum aestivum) genome has been produced by sequencing isolated chromosome arms. We have annotated 124,201 gene loci distributed nearly evenly across homeologous chromosomes and subgenomes. Comparative analysis subgenomes extant diploid tetraploid relatives showed that high similarity structural conservation are retained, with limited loss, after polyploidization. However, genomes there was evidence dynamic gain,...

10.1126/science.1251788 article EN Science 2014-07-17
Thomas Marcussen Simen R. Sandve Lise Heier M. Spannagl Matthias Pfeifer and 94 more Kjetill S. Jakobsen Brande B. H. Wulff Burkhard Steuernagel Klaus Mayer Odd-Arne Olsen Jane Rogers Jaroslav Doležel Curtis Pozniak Kellye Eversole Catherine Feuillet Bikram Gill Bernd Friebe Adam J. Lukaszewski Pierre Sourdille Takashi R. Endo Marie Kubaláková Jarmila Číhalíková Zdeňka Dubská Jan Vrána Romana Šperková Hana Šimková Melanie Febrer Leah Clissold Kirsten McLay Kuldeep Singh Parveen Chhuneja Nagendra Kumar Singh Jitendra P. Khurana Eduard Akhunov Frédéric Choulet Adriana Alberti Valérie Barbe Patrick Wincker Hiroyuki Kanamori Fuminori Kobayashi Takeshi Itoh Takashi Matsumoto Hiroaki Sakai Tsuyoshi Tanaka Jian Wu Yasunari Ogihara Hirokazu Handa P. Ron Maclachlan Andrew Sharpe Darrin Klassen David Edwards Jacqueline Batley Sigbjørn Lien Mario Cáccamo Sarah Ayling Ricardo H. Ramírez-González Bernardo Clavijo Jonathan Wright Mihaela M. Martis Martin Mascher Jarrod Chapman Jesse Poland Uwe Scholz Kerrie Barry Robbie Waugh Daniel S. Rokhsar Gary J. Muehlbauer Nils Stein Heidrun Gundlach Matthias Zytnicki Véronique Jamilloux Hadi Quesneville Thomas Wicker Primetta Faccioli Moreno Colaiacovo A. M. Stanca Hikmet Budak Luigi Cattivelli Natasha Glover Lise Pingault Etienne Paux Sapna Sharma R. Appels M. Bellgard Brett Chapman Thomas Nussbaumer Kai Christian Bader Hélène Rimbert Shichen Wang R. E. Knox Andrzej Kilian Michaël Alaux Françoise Alfama L.J. Couderc Nicolas Guilhot Claire Viseux Mikaël Loaec Beat Keller Sébastien Praud

The allohexaploid bread wheat genome consists of three closely related subgenomes (A, B, and D), but a clear understanding their phylogenetic history has been lacking. We used assemblies five diploid relatives to analyze genome-wide samples gene trees, as well estimate evolutionary relatedness divergence times. show that the A B genomes diverged from common ancestor ~7 million years ago these gave rise D through homoploid hybrid speciation 1 2 later. Our findings imply present-day is product...

10.1126/science.1250092 article EN Science 2014-07-17
Matthias Pfeifer Karl Kugler Simen R. Sandve Bujie Zhan Heidi Rudi and 95 more Torgeir R. Hvidsten Klaus Mayer Jane Rogers Jaroslav Doležel Curtis Pozniak Kellye Eversole Catherine Feuillet Bikram Gill Bernd Friebe Adam J. Lukaszewski Pierre Sourdille Takashi R. Endo Marie Kubaláková Jarmila Číhalíková Zdeňka Dubská Jan Vrána Romana Šperková Hana Šimková Melanie Febrer Leah Clissold Kirsten McLay Kuldeep Singh Parveen Chhuneja Nisha Singh Jitendra P. Khurana Eduard Akhunov Frédéric Choulet Adriana Alberti Valérie Barbe Patrick Wincker Hiroyuki Kanamori Fuminori Kobayashi Takeshi Itoh Takashi Matsumoto Hiroaki Sakai Tsuyoshi Tanaka Jian Wu Yasunari Ogihara Hirokazu Handa P. Ron Maclachlan Andrew Sharpe Darrin Klassen David Edwards Jacqueline Batley Odd-Arne Olsen Sigbjørn Lien Burkhard Steuernagel Brande B. H. Wulff Mario Cáccamo Sarah Ayling Ricardo H. Ramírez-González Bernardo Clavijo Jonathan Wright M. Spannagl Mihaela M. Martis Martin Mascher Jarrod Chapman Jesse Poland Uwe Scholz Kerrie Barry Robbie Waugh Daniel S. Rokhsar Gary J. Muehlbauer Nils Stein Heidrun Gundlach Matthias Zytnicki Véronique Jamilloux Hadi Quesneville Thomas Wicker Primetta Faccioli Moreno Colaiacovo A. M. Stanca Hikmet Budak Luigi Cattivelli Natasha Glover Lise Pingault Etienne Paux Sapna Sharma R. Appels M. Bellgard Brendan Chapman Thomas Nussbaumer Kai Christian Bader Hélène Rimbert Shichen Wang R. E. Knox Andrzej Kilian Michaël Alaux Françoise Alfama L.J. Couderc Nicolas Guilhot Claire Viseux Mikaël Loaec Beat Keller Sébastien Praud

Allohexaploid bread wheat ( Triticum aestivum L.) provides approximately 20% of calories consumed by humans. Lack genome sequence for the three homeologous and highly similar genomes (A, B, D) has impeded expression analysis grain transcriptome. We used previously unknown information to analyze cell type–specific genes in developing identified distinct co-expression clusters reflecting spatiotemporal progression during endosperm development. observed no global but type– stage-dependent...

10.1126/science.1250091 article EN Science 2014-07-17

The Wheat@URGI portal has been developed to provide the international community of researchers and breeders with access bread wheat reference genome sequence produced by International Wheat Genome Sequencing Consortium. browsers, BLAST, InterMine tools have established for in-depth exploration together additional linked datasets including physical maps, variations, gene expression, genetic phenomic data from other collaborative projects already stored in GnpIS information system. provides...

10.1186/s13059-018-1491-4 article EN cc-by Genome biology 2018-08-14

Thanks to their ability move around and replicate within genomes, transposable elements (TEs) are perhaps the most important contributors genome plasticity evolution. Their detection annotation considered essential in any sequencing project. The number of fully sequenced genomes is rapidly increasing with improvements high-throughput technologies. A automated de novo process for TEs therefore required cope deluge sequence data. However, all procedures error-prone, an procedure TE...

10.1186/s13100-019-0150-y article EN cc-by Mobile DNA 2019-01-29

Endogenous viral elements (EVEs) are sequences that integrated in the nuclear genomes of their hosts and signatures infections may have occurred millions years ago. The study EVEs, coined paleovirology, provides important insights into virus evolution. Caulimoviridae is most common group EVEs plants, although presence has often been overlooked plant genome studies. We refined methods for identification caulimovirid interrogated a broad diversity taxa, from algae to advanced flowering plants....

10.1038/s41598-017-16399-x article EN cc-by Scientific Reports 2018-01-08

Abstract The Wheat@URGI portal ( https://wheat-urgi.versailles.inra.fr ) has been developed to provide the international community of researchers and breeders with access bread wheat reference genome sequence produced by International Wheat Genome Sequencing Consortium. browsers, BLAST, InterMine tools have established for in depth exploration together additional linked datasets including physical maps, variations, gene expression, genetic phenomic data from other collaborative projects...

10.1101/363259 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2018-07-06

Abstract Endogenous viral elements (EVEs) are sequences that integrated in the nuclear genomes of their hosts and signatures infections may have occurred millions years ago. The study EVEs, coined paleovirology, provides important insights into virus evolution. Caulimoviridae is most common group EVEs plants, although presence has often been overlooked plant genome studies. We refined methods for identification caulimovirid interrogated a broad diversity taxa, from algae to advanced...

10.1101/158972 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2017-07-04
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