A5100676632- Advanced Machining and Optimization Techniques
- Advanced Surface Polishing Techniques
- Advanced machining processes and optimization
- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Pharmacological Effects of Natural Compounds
- Nanoparticle-Based Drug Delivery
- Climate Change and Health Impacts
- Natural product bioactivities and synthesis
- Advanced DC-DC Converters
- Flavonoids in Medical Research
- Berberine and alkaloids research
- Traditional Chinese Medicine Analysis
- High-Temperature Coating Behaviors
- Lung Cancer Diagnosis and Treatment
- Electrodeposition and Electroless Coatings
- Meat and Animal Product Quality
- Stability and Control of Uncertain Systems
- High Entropy Alloys Studies
- Drug Solubulity and Delivery Systems
- Advanced Algorithms and Applications
- RNA Interference and Gene Delivery
- Electromagnetic wave absorption materials
- Ocular Surface and Contact Lens
- Nanoplatforms for cancer theranostics
Tianjin University of Traditional Chinese Medicine
2016-2025
Tianjin haihe hospital
2022-2025
Sichuan University
2008-2025
University of Science and Technology Beijing
2025
Eighth Affiliated Hospital of Sun Yat-sen University
2023-2025
Sun Yat-sen University
2018-2025
Chinese Academy of Sciences
2016-2025
University of Chinese Academy of Sciences
2020-2025
Xuzhou Medical College
2021-2025
Chengdu Institute of Biology
2020-2025
Abstract The transient precorneal retention time and low penetration capacity into intraocular tissues are the key obstacles that hinder ophthalmic drug delivery of many therapeutic compounds, especially for drugs with poor solubility permeability. To break stalemate, N-acetyl-L-cysteine functionalized chitosan copolymer (CS-NAC), which exhibit marked bioadhesion permeation enhancing effect, was synthesized. curcumin encapsulated NLC (CUR-NLC) produced optimized followed by surface...
A highly efficient one-pot strategy has been developed for the synthesis of β-ketophosphonates directly from alkynes and dialkyl H-phosphonates in presence widely available AgNO3/CuSO4 K2S2O8 at room temperature under open-air conditions.
Human bone cells live in a complex environment, and the biomimetic design of porous structures attached to implants is high demand. Porous based on Voronoi tessellation with potential are gradually used repair scaffolds. In this study, mechanical properties permeability trabecular-like scaffolds different porosity levels average apertures were analyzed. The bone-implant evaluated using finite element analysis compression experiment, was studied by computational fluid dynamics. Finally,...
Abstract Background Hippocampal damage caused by status epilepticus (SE) can bring about cognitive decline and emotional disorders, which are common clinical comorbidities in patients with epilepsy. It is therefore imperative to develop a novel therapeutic strategy for protecting hippocampal after SE. Mitochondrial dysfunction one of contributing factors Given the benefits mitochondrial replenishment exogenous mitochondria, we hypothesized that transplantation mitochondria would be capable...
Dissolved gas analysis (DGA) in transformer oil, which analyzes its content, is valuable for promptly detecting potential faults oil-immersed transformers. Given the limitations of traditional fault diagnostic methods, such as insufficient characteristic components and a high misjudgment rate faults, this study proposes diagnosis model based on multi-scale approximate entropy optimized convolutional neural networks (CNNs). This introduces an improved sparrow search algorithm (ISSA)...
Abstract Macrophage polarization and energy metabolic reprogramming play pivotal roles in the onset progression of inflammatory arthritis. Moreover, although previous studies have reported that proviral integration Moloney virus 2 (Pim2) kinase is involved various cancers through mediation aerobic glycolysis cancer cells, its role arthritis remains unclear. In this study, we demonstrated multiple enzymes are activated upon Pim2 upregulation during M1 macrophage polarization. Specifically,...
Purpose: To prepare and evaluate the solid lipid nanoparticles of baicalin (BA-SLN) for ocular drug delivery system. Methods: The BA-SLN was prepared by emulsification/ultrasonication method. appearance examined negative stain mean diameter zeta potential were determined using a Zetasizer. entrapment efficiency Sephadex-G50 column. And solid-state characterization analyzed DSC X-ray. release from evaluated dialysis bag diffusion technique. effects SLN on corneal permeability investigated in...
Two integrated high-speed gate drivers to enable high-frequency operation of synchronous rectifiers in high-voltage switching power converters are presented this paper. The first driver for a CMOS train consists capacitively coupled level shifter (CCLS) that offers negligible propagation delays and no static current consumption, requires only one off-chip capacitor high-side pMOS driving capability without any external floating supply. second low-power dynamically controlled (DCLS) with...
Baicalein (BE) is one of the main active flavonoids representing variety pharmacological effects including anticancer, anti-inflammatory and cardiovascular protective activities, but it's very low solubility, dissolution rate poor oral absorption limit therapeutic applications. In this work, a nano-cocrystal strategy was successfully applied to improve bioavailability BE. Baicalein-nicotinamide (BE-NCT) nano-cocrystals were prepared by high pressure homogenization evaluated both in vitro...