A5013627398- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Neurological disorders and treatments
- Birth, Development, and Health
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Neural Engineering
- Cancer Risks and Factors
- Maternal and fetal healthcare
- Congenital Heart Disease Studies
- Air Quality and Health Impacts
- Neonatal and fetal brain pathology
- Prenatal Screening and Diagnostics
- Transcranial Magnetic Stimulation Studies
- Bariatric Surgery and Outcomes
- Reproductive Biology and Fertility
- Inflammatory mediators and NSAID effects
- Effects and risks of endocrine disrupting chemicals
- AI in cancer detection
- Cancer Immunotherapy and Biomarkers
- Ovarian function and disorders
- Genetic Neurodegenerative Diseases
- MRI in cancer diagnosis
- Industrial Vision Systems and Defect Detection
- COVID-19 Impact on Reproduction
- VLSI and Analog Circuit Testing
Parkinson’s Disease and Movement Disorder Center of Silicon Valley
2023
University of Southern California
2018-2021
Sri Krishnadevaraya University
2021
Vijayanagara Sri Krishnadevaraya University
2021
University of California, Irvine
2020
GlobalFoundries (Germany)
2017
Nottingham University Hospitals NHS Trust
2010-2013
University of Nottingham
2010-2013
Queen's Medical Centre
2011
Weatherford College
2011
Objective To study whether maternal cigarette smoking during pregnancy is associated with alterations in the growth of fetal lungs, kidneys, liver, brain, and placenta. Design A case-control study, operators performing image analysis blinded. Setting Study performed on a research-dedicated magnetic resonance imaging (MRI) scanner (1.5 T) participants recruited from large teaching hospital United Kingdom. Participants total 26 pregnant women (13 current smokers, 13 non smokers) were...
Deep brain stimulation (DBS) for secondary (acquired, combined) dystonia does not reach the high degree of efficacy achieved in primary (genetic, isolated) dystonia. We hypothesize that this may be due to variability underlying injury, so different children require placement electrodes regions basal ganglia and thalamus. describe a new targeting procedure which temporary depth are placed at multiple possible targets thalamus, probing is performed using test recording while remain one week an...
To assess the reliability of magnetic resonance imaging (MRI) to measure fetal fat volume in utero, and study growth women with without diabetes view increased prevalence macrosomia former.We studied 26 pregnant women, 14 pre-gestational 12 non-diabetic controls. Fetal assessment took place at 24 weeks' gestation again 34 weeks by standard ultrasound biometry followed MRI 1.5 T. was determined from T1-weighted water-suppressed images using a semi-automated approach based on pixel intensity...
We analysed 46 telecytology cases sent from two rural hospitals about 500 km a tertiary cancer centre. The were submitted for second opinion over period of years and evaluated using static store forward approach. A total 715 digital images studied (average 15 per case). Forty-one the (89%) reported within 3 days 54% one working day. aspiration smears found to be diagnosable quality in 89 93% cases, respectively. diagnostic concordance was assessed by comparing diagnosis, glass slide...
Introduction Torsion of the spleen is a rare cause abdominal pain. Predisposition occurs following abnormal development splenic suspensory ligaments. We report case torsion in sited normal anatomical position and discuss latest treatment options. To best our knowledge, this has not been reported literature to date. Case Presentation A 73-year-old Caucasian woman presented department with sudden onset, severe, left-upper An enhanced computed tomography revealed an unenhancing spleen. She...
Deep brain stimulation is an elective surgical intervention that improves the function and quality of life in children with dystonia other movement disorders. Both basal ganglia thalamic nuclei have been found to be relevant targets for treatment children, including ventral intermediate nucleus thalamus, which can control dystonic spasms. Electrophysiological confirmation correct electrode location within ventralis thus important success outcome. The present work shows evoked potentials...
Introduction: Pelvic ultrasonography remains the non-invasive imaging modality of choice for detecting and characterising adnexal masses. The use Doppler ultrasound has improved differential diagnosis ovarian disease helped to widen understanding aetiology possible pathophysiology various underlying conditions with an aim management. Areas covered: This review describes basis different techniques their application in disease. present evidence is critically analysed attempt define current...
Abstract High-frequency peripheral nerve stimulation has emerged as a noninvasive alternative to thalamic deep brain for some patients with essential tremor. It is not known whether such techniques might be effective movement disorders in children, nor the mechanism and transmission of stimuli central structures understood. This study was designed investigate fidelity from nerves nuclei children dystonia undergoing surgery. The ventralis intermediate (VIM) thalamus showed robust evoked...
Many patients with Parkinson's disease (PD) experience action tremor (including postural and kinetic tremors) that impair activities of daily living. Transcutaneous afferent patterned stimulation (TAPS) is a non-invasive neuromodulation therapy modulates tremorgenic activity at the ventral intermediate nucleus (VIM). Most TAPS evidence evaluated relief associated essential (ET). This study whether results in similar PD.Forty PD tremors were enrolled prospective, single-arm, open-label four...
This study evaluated efficacy and safety of transcutaneous afferent patterned stimulation (TAPS) to reduce postural kinetic tremors in Parkinson's disease (PD) patients.
In maternal diabetes the placenta is large with abnormal vascular development and increased villous volume. The aim of this study was to use a novel stereological 3D power Doppler ultrasound technique investigate differences in-vivo in fractional volume placental blood vessels (FrVolBV) between women without diabetes. 20 normal 17 pre-gestational diabetes, anterior placentae were recruited. Subjects matched for age, BMI parity. Each subject had scans every 4 weeks 32 gestation using Voluson...
<h3>Abstract</h3> <h3>Background</h3> Corona virus has literally travelled “around the world in 80 days” akin to Fogg and Passepartoute of Jules Verne fame. Manning corona disease 2019 (COVID-19) wards ICUs, also surgery on COVID-positive patients is increasingly being relegated that subset health care workers (HCW) who themselves have resumed duties after surviving COVID-19 infection. Convalescent plasma therapy been widely endorsed. Several vaccines are pipeline as potential preventive...
3D power Doppler angiography (3DPD) is used to quantify the vascularity of an organ. Analysis a stored dataset can be reliable but few studies have considered reliability data acquisition. Our aim was investigate intra- and interobserver reproducibility serial acquisition 3DPD whole placenta from women at 12 20 weeks gestation. We hypothesised high level agreement would exist. low risk with uncomplicated, viable singleton pregnancy were scanned (Voluson 730 Expert) two gestational age...
Triclosan (TCN) was evaluated for reproductive and developmental toxicity on male female performance such as gonadal function, mating behaviour, conception, development of the conceptus parturition. Wistar rats (10/sex/dose) were administered by oral gavage at dose levels 0, 25, 75 150 mg/kg bwt/day, prior to mating, during post-mating periods (for males), pregnancy up lactation day 13 females). The results showed that, no treatment related mortality or clinical signs. Body weight, food...
In maternal diabetes the placenta is large with abnormal vascular development and increased villous volume. A prospective, longitudinal observational study of 3D power Doppler indices was performed to investigate differences in-vivo in placental vascularity between women without diabetes. 28 normal 20 pre-gestational diabetes, were recruited. Each subject had 3 scans 12 weeks gestation using a Voluson 730 Expert scanner. The VOCAL tool within 4D View (GE Medical Systems) used outline plane...