- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Tracheal and airway disorders
- Advanced Proteomics Techniques and Applications
- Influenza Virus Research Studies
- Metabolomics and Mass Spectrometry Studies
- Mass Spectrometry Techniques and Applications
- COVID-19 Impact on Reproduction
- COVID-19 and healthcare impacts
- Nail Diseases and Treatments
- Respiratory Support and Mechanisms
- Immune responses and vaccinations
- COVID-19 epidemiological studies
- Global Maternal and Child Health
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- Antifungal resistance and susceptibility
- Pneumonia and Respiratory Infections
- Hepatitis C virus research
- Fungal Infections and Studies
- Vaccine Coverage and Hesitancy
- Bacterial Infections and Vaccines
- Child Nutrition and Water Access
- Diverse Scientific Research Studies
University of Sierra Leone
2024
MRC Unit the Gambia
2013-2023
Donka Hospital
2019
Cutaneous fungal infections are very common, especially in poorer communities and with intercurrent HIV infection. Determining the pathogen skin-related neglected tropical diseases (NTDs) determines optimal therapy. We undertook a country survey across many African countries to determine diagnostic capacity for skin diseases.A detailed questionnaire was delivered contacts collect data on availability, frequency, location of testing key procedures followed up 2 rounds validation by video call...
Hepatocellular Carcinoma is the third most common cause of cancer related death worldwide, often diagnosed by measuring serum AFP; a poor performance stand-alone biomarker. With aim improving on this, our study focuses plasma proteins identified Mass Spectrometry in order to investigate and validate differences seen respective proteomes controls subjects with LC HCC.
SARS-CoV-2 transmission in sub-Saharan Africa has probably been underestimated. Population-based seroprevalence studies are needed to determine the extent of continent.
In 1997, The Gambia introduced three primary doses of Haemophilus influenzae type b (Hib) conjugate vaccine without a booster in its infant immunisation programme along with establishment population-based surveillance on Hib meningitis the West Coast Region (WCR). This was stopped 2002 reported elimination disease. re-established 2008 but again 2010. We aimed to re-establish WCR and continue Basse Health Demographic Surveillance System (BHDSS) east country assess any shifts epidemiology...
<ns4:p><ns4:bold>Background:</ns4:bold> In many countries,<ns4:italic> </ns4:italic>non-pharmaceutical interventions to limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission resulted in significant reductions other viruses. However, similar data from Africa are limited. We explored the extent which viruses such as influenza and rhinovirus co-circulated with SARS-CoV-2 The Gambia during COVID-19 pandemic. </ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: Between April...
<ns3:p><ns3:bold>Background:</ns3:bold> In many countries,<ns3:italic> </ns3:italic>non-pharmaceutical interventions to limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission resulted in significant reductions other viruses. However, similar data from Africa are limited. We explored the extent which viruses such as influenza and rhinovirus co-circulated with SARS-CoV-2 The Gambia during COVID-19 pandemic. </ns3:p><ns3:p> <ns3:bold>Methods</ns3:bold>: Between April...
Background: Hepatocellular Carcinoma is the third most common cause of cancer related death worldwide, often diagnosed by measuring serum AFP; a poor performance stand-alone biomarker.With aim improving on this, our study focuses plasma proteins identified Mass Spectrometry in order to investigate and validate differences seen respective proteomes controls subjects with LC HCC.Methods: analysis using liquid chromatography electro spray ionization quadrupole time-of-flight was conducted 339...
Abstract Objectives SARS-CoV-2 transmission in Sub-Saharan Africa has probably been underestimated. Population-based seroprevalence studies are needed to determine the extent of continent. Methods Blood samples from a cohort Gambian pregnant women were tested for total IgM/IgG before ( Pre-pandemic1: October-December 2019 and Pre-pandemic2: February-June 2020) during pandemic Post-wave1 : 2020, Post-wave2: May-June 2021; Post-wave3 2021). Samples positive protein-specific antibodies. Results...
Background: The coronavirus disease (COVID-19) pandemic resulted in an unprecedent global response for the development of COVID-19 vaccines. However, as viral mutations continue to occur, potentially decreasing efficacy currently available vaccines, and inequity vaccine access continues, identifying safe effective drugs minimise severity remains a priority. Methods: We designed adaptive individually randomised single blinded non identical placebo-controlled trial evaluate safety repurposing...
<ns3:p><ns3:bold>Background:</ns3:bold> In many countries,<ns3:italic> </ns3:italic>non-pharmaceutical interventions to limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission resulted in significant reductions other viruses. However, similar data from Africa are limited. We explored the extent which viruses such as influenza and rhinovirus co-circulated with SARS-CoV-2 The Gambia during COVID-19 pandemic. </ns3:p><ns3:p> <ns3:bold>Methods</ns3:bold>: Between April...