- Congenital gastrointestinal and neural anomalies
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Protein Tyrosine Phosphatases
- Renal function and acid-base balance
- Urological Disorders and Treatments
- Infectious Encephalopathies and Encephalitis
- Congenital Diaphragmatic Hernia Studies
- Electrolyte and hormonal disorders
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Pelvic floor disorders treatments
- Ottoman and Turkish Studies
- Ocular Diseases and Behçet’s Syndrome
- Hereditary Neurological Disorders
- Acute Kidney Injury Research
- Skin and Cellular Biology Research
- Hair Growth and Disorders
- Kawasaki Disease and Coronary Complications
- Potassium and Related Disorders
- Methemoglobinemia and Tumor Lysis Syndrome
- Historical Turkish Studies
- RNA modifications and cancer
- Metallurgy and Cultural Artifacts
- Intensive Care Unit Cognitive Disorders
Atatürk University
2005-2024
Erzurum Regional Training and Research Hospital
2013-2022
Ondokuz Mayıs University
2018
This study aims to investigate the protective effect of roflumilast, a phosphodiesterase (PDE)-4 enzyme inhibitor, and demonstrate its possible role in development prevention cerebral ischemia/reperfusion injury (CI/RI) after stroke induced by carotid artery ligation juvenile rats. The rats were randomly divided into five groups: healthy group without any treatment, administered with 1 mg/kg CI not 0.5 roflumilast. In groups, reperfusion was achieved 2h ischemia induction; roflumilast this...
Leptospirosis, a zoonosis, is characterized by wide range of clinical and laboratory findings, varying from self-limiting infection to potentially fatal disease. Leptospirosis-related manifestations, except for Weil's disease, may often be overlooked due their nonspecificity in children. Additionally, many health-care professionals lack awareness leptospirosis. This paper presents case leptospirosis that was initially misdiagnosed as staphylococcal toxic shock syndrome. The literature on...
Adiponectin and its receptors are known to be expressed in osteoblasts may have important functions normal bone cells. The aim of this study was investigate the effect vitamin D therapy on serum adiponectin levels children with deficiency rickets (VDDR).21 patients VDDR were included study. Patients treated 300,000 U D3 (IM) calcium lactate (50mg/kg/ day, PO, for 10 days). Anthropometric parameters biochemical markers including (Ca), phosphorus (P), alkaline phosphatase (ALP), intact...
The study area is located in the Eastern Pontides between Rize, Çayeli, Arhavi, İspir and İkizdere. In this area, Maçka Tectonic Slice (MTS) Taşköprü (TTS) are exposed. MTS composed from old to young; Late Jurassic-Early Cretaceous limestone (Berdiga fm.); Turonian- Santonian conglomerate, sandstone, micritic limestone, siltstone, marl, basaltic, basaltic-andesitic lava, pyroclastites (Çatak rhyolitic, dacitic pyroclastites, clayey (Kızılkaya late Santonian-Campanian andesitic (Caglayan...
Hydrocephalus is a rare complication of mumps. We report an 8.5-year-old boy with acute hydrocephalus associated mumps meningoencephalitis.
Introduction:There is no regional study presenting the pediatric intoxication cases followed in intensive care units (PICUs).As they show features, we aimed to present our PICU, and indicate self-constituted protocol about PICU admission rules these patients.Methods: Demographic, clinical laboratory data of patients who admitted with between October 2015 2017 were noted.PICU indications evaluated.Results: Twenty-four (14%) 171 formed group.Fourteen (58.3%) female.Ten (41.7%) under 5 years...
A sepsis model was created, induced by cecal ligation and puncture (CLP), in juvenile rat groups. Milrinone (MIL), which is known to have a modulatory effect on pro-inflammatory cytokines, administered the designated groups early period before severe developed. The study aimed at investigating possible protective effects of milrinone lung kidney tissues rats late phase sepsis.The pups were divided into seven with six animals each group: (1) healthy who received no drug; (2) CLP-S12...
Acute-on-chronic liver failure and its outcomes have not yet been evaluated in detail children. We aimed to evaluate the etiology, acute events, prognostic factors of acute-on-chronic children.Pediatric patients (age 2-18 years) diagnosed with between April 2014 2020 were retrospectively. was defined as presence hepatic insult previously or undiagnosed chronic disease causing jaundice (total serum bilirubin ≥5 mg/dL) coagulopathy (international normalized ratio ≥2.0) clinical and/or...
This study focused on delineating the possible effects of roflumilast (ROF), a selective phosphodiesterase 4 (PDE4) inhibitor, in rats with cecal ligation and puncture (CLP)-induced polymicrobial sepsis, investigated whether ROF can act as protective agent sepsis-induced lung damage.Four experimental groups were organized, each comprising eight rats: Control, Sepsis, Sepsis + 0.5 mgkg-1, 1 mgkg-1 groups. A sepsis model was induced by under anesthesia. Twelve hours after induction, lungs...
Turk saglik sistemi 2003 yilinda baslatilan Saglikta Donusum Programiyla (SDP), reform olarak adlandirilan koklu bir degisiklik gecirmistir. SDP’yle birinci basamak hizmetlerinin sunumundaki ve organizasyonundaki yonetim anlayisi yeniden tasarlanmis Aile Hekimligi (AH) sistemine uygulamaya konulmustur. sayesinde, Turkiye’de hizmetlerine ulasiminin kolaylastirilmasi, kuruluslarinda kalitenin etkinligin arttirilmasi planlanmaktadir. Bu calismanin amaci, AH oncesi sonrasinda, kuruluslarindan...
Introduction:The aim of this study was to identify demographic and clinical characteristics patients who were subjected plasma exchange (PE) at our unit, investigate the effect these factors on treatment outcome patient prognosis.Methods: Demographic, laboratory data PE between January 2012 August 2015 obtained from hospital information system, medical records apheresis unit.Results: Plasma performed in 40 for 168 times throughout study.The median age 9.4 (range: 1.5-17.3)years, with a...
Objectives:To analyze the course of seasonal viral infections respiratory tract in patients hospitalized pediatric intensive care units (PICU) 16 centers Turkey.Materials and methods: It is a retrospective, observational, multicenter study conducted tertiary PICUs Turkey includes total 302 children with cause nasal swab which required PICU admission no interventions.Results: Median age was 12 months.Respiratory syncytial virus (RSV) more common over one year whereas influenza, human...
Foreign body aspiration (FBA) in childhood is a life-threatening condition that necessitates prompt management to prevent devastating complications. Different imaging methods are used the diagnosis of FBA.The aim this study was compare diagnostic value and dose microsievert wide-volume computed tomography (μSv-WV-CT) with multidetector using an automatic exposure control system (MDCT-AEC) children FBA.In single-center cross-sectional study, 102 cases diagnosed FBA between September 2013 2021...
Akut bilinç kaybı çocuklarda hayatı tehdit eden önemli bir durumdur. Santral sinir sistemi enfeksiyonları, intoksikasyonlar, metabolik-endokrin nedenler, status epileptikus, intrakranial kanamalar ve kitleler kaybının nedenleri arasındadır. Bu olgu sunumu akut ile başvuran hastalarda öncesinde hiçbir belirti semptom olmasa bile tümörlerin akılda tutulması gerektiğine dikkat çekmektedir.
Central diabetes insipidus is characterized by polydipsia polyuria dehydration irritability poor feeding failure to thrive and hypernatremia This disease caused lack of antidiuretic hormone Here a very low birth weight premature infant who developed central secondary pituitary hemorrhage in the newborn period was treated successfully with intranasal desmopressin acetate presented It emphasized that might be an effective method also treatment infants Turk Arch Ped 2013; 48: 241 243