A5027260270- Clostridium difficile and Clostridium perfringens research
- Microscopic Colitis
- Gut microbiota and health
- Gastrointestinal motility and disorders
- Nosocomial Infections in ICU
- Helicobacter pylori-related gastroenterology studies
- Geriatric Care and Nursing Homes
- Intensive Care Unit Cognitive Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Mental Health and Patient Involvement
Aarhus University Hospital
2020-2024
Aarhus University
2021-2023
Central Denmark Region
2021
Abstract Purpose Clostridioides difficile infection (CDI) has a high mortality among older patients. Identification of patients with CDI in increased risk is important to target treatment and thereby reduce mortality. The aim this study was investigate rates compare frailty levels at discharge, measured by the record-based Multidimensional Prognostic Index (MPI), age severity as predictors diagnosed during hospitalisation. Methods This population-based cohort from Central Denmark Region,...
Abstract Background During care transitions, the older (75+) patient’s agenda can easily be missed. To counteract this, involving patients in shared clinical decision making has proven to of great value. Likewise, and other stakeholders as researchers is gaining ground. Patient public involvement (PPI) research entails many benefits, for example, by bringing further insight from those with lived experiences being ill. There are various challenges associated some patients, example frailty,...
Clostridioides (Clostridium) difficile infection (CDI) is a leading cause of antibiotics-associated diarrhoea. Faecal microbiota transplantation (FMT) effective for recurrent CDI and may be provided as home treatment to frail, older people.We present four consecutive patients with CDI, treated at using nasojejunal tube-delivered or encapsulated donor faeces. The primary outcome was combined clinical resolution negative CD toxin test 8 weeks post-treatment.All had severe all improved...
<title>Abstract</title> <bold>Background</bold>:<italic>Clostridioides difficile</italic>infection (CDI) is complex and associated with adverse clinical outcomes in older patients, including increased mortality rates. Effective transition of care for patients CDI critical to improve survival health reduce recurrence The aim this study investigate the effects a geriatric tailored intervention on patient survival, compared who receive usual care.<bold>Methods</bold>: This quality improvement...
Background: Clostridioides difficile infection (CDI) is associated with high mortality. Faecal microbiota transplantation (FMT) an established treatment for recurrent CDI, but its use first or second CDI remains experimental. We investigated the effectiveness of FMT in a real-world clinical setting.Methods: This multi-site Danish cohort study included patients treated from June 2019 to February 2023. Follow-up concluded on 31 August Outcome data were retrieved electronic medical records. The...