Lawrence M. Brown

ORCID: 0000-0003-4532-7640
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About
Contact & Profiles
Research Areas
  • Pharmaceutical Practices and Patient Outcomes
  • Medication Adherence and Compliance
  • Health Systems, Economic Evaluations, Quality of Life
  • Radiation Dose and Imaging
  • Radioactivity and Radon Measurements
  • Pharmaceutical studies and practices
  • Healthcare Policy and Management
  • Patient Satisfaction in Healthcare
  • Health Literacy and Information Accessibility
  • Pharmaceutical Economics and Policy
  • Climate Change and Health Impacts
  • Innovations in Medical Education
  • Medical Education and Admissions
  • Pharmacy and Medical Practices
  • Pharmaceutical industry and healthcare
  • Patient Safety and Medication Errors
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Behavioral Health and Interventions
  • Biomedical Ethics and Regulation
  • Mobile Health and mHealth Applications
  • Primary Care and Health Outcomes
  • Complementary and Alternative Medicine Studies
  • Racial and Ethnic Identity Research
  • Statistical Methods in Clinical Trials
  • Bone health and osteoporosis research

Chapman University
2015-2024

University of California, San Francisco
2022

University of Maryland, Baltimore
2005-2021

United States Department of Veterans Affairs
1990-2017

University of Tennessee Health Science Center
2003-2013

Medication Management (United States)
2007-2010

University of Tennessee at Knoxville
2006-2010

University of Minnesota
2002-2008

Twin Cities Orthopedics
2003

University of Tennessee System
2003

Objective: To describe the prevalence of herbal medicine use among US adults and to assess factors associated with predictors use. Design: The data for products were collected from 2015 National Consumer Survey on Medication Experience Pharmacists’ Roles. Chi-square test was used analyz use, assessed logistic regression analysis. Results: Factors supplement include age older than 70, having a higher high school education, using prescription medications or over-the-counter (OTC) medications,...

10.1177/2374373517706612 article EN cc-by-nc Journal of Patient Experience 2017-06-05

Medical surveillance of a group U.S. Gulf War veterans who were victims depleted uranium (DU) "friendly fire" has been carried out since the early 1990s. Findings to date reveal persistent elevation urine uranium, more than 10 yr after exposure, in those with retained shrapnel fragments. The excretion is presumably from ongoing mobilization DU fragments oxidizing situ. Other clinical outcomes related measures have revealed few abnormalities. Renal function normal despite kidney's expected...

10.1080/15287390490273541 article EN Journal of Toxicology and Environmental Health 2004-02-01

Despite a substantial evidence base, implementation of pharmacogenetics into routine patient care has been slow due to number non‐trivial practical barriers. We implemented Personalized Anti‐platelet Pharmacogenetics Program (PAP3) for cardiac catheterization patients at the University Maryland Medical Center and Baltimore Veterans Administration Patients' are offered CYP2C19 genetic testing, which is performed in our Clinical Laboratory Improvement Amendment (CLIA)‐certified Translational...

10.1002/ajmg.c.31396 article EN American Journal of Medical Genetics Part C Seminars in Medical Genetics 2014-03-01

The increasing number and high prices of orphan drugs have triggered concern among patients, payers, policymakers about the affordability new approved using incentives set by Orphan Drug Act (ODA) 1983. This study evaluated factors associated to differences in treatment cost non-orphan FDA from 2017 2021. A generalized linear model (GLM) with Gamma log-link analysis was used ascertain association drug characteristics costs drugs. results showed that median interquartile range (IQR) USD...

10.3390/healthcare11040558 article EN Healthcare 2023-02-13

Background: Collaboration between physicians and pharmacists is one approach to address drug-related morbidity achieve therapeutic goals.A collaborative practice of pharmaceutical care has been used in the Fairview Clinics System Minneapolis-St Paul since 1999.Methods: The quality determinations made by within this was studied a 12-member panel who randomly selected patient records.This improvement process validation component study evaluating effects drug therapy management patients...

10.1001/archinte.163.15.1813 article EN Archives of Internal Medicine 2003-08-11

To determine clinical health effects in a small group of US Gulf War veterans (n = 50) who were victims depleted uranium (DU) "friendly fire," we performed periodic medical surveillance examinations. We obtained urine determinations, laboratory values, reproductive measures, neurocognitive assessments, and genotoxicity measures. DU-exposed with retained metal shrapnel fragments excreting elevated levels 8 years after their first exposure (range, 0.018 to 39.1 μg/g creatinine for vs 0.002...

10.1097/00043764-200112000-00001 article EN Journal of Occupational and Environmental Medicine 2001-12-01

As part of a longitudinal surveillance program, 35 members larger cohort 77 Gulf War I veterans who were victims depleted uranium (DU) "friendly fire" during combat underwent 3-day clinical assessment at the Baltimore Veterans Administration Medical Center (VAMC). The included detailed medical history, exposure physical examination, and laboratory studies. Spot 24-h urine collections obtained for renal function parameters (U) measures. Blood U measures also performed. Urine excretion was...

10.1080/15287390802445400 article EN Journal of Toxicology and Environmental Health 2008-11-02

A cohort of seventy-four 1991 Gulf War soldiers with known exposure to depleted uranium (DU) resulting from their involvement in friendly-fire incidents DU munitions is being followed by the Baltimore Veterans Affairs Medical Center. Biennial medical surveillance visits designed identify uranium-related changes health have been conducted since 1993. On-going systemic veterans embedded metal fragments indicated elevated urine (U) excretion at concentrations up 1,000-fold higher than that seen...

10.1097/01.hp.0000259850.66969.8c article EN Health Physics 2007-06-08

As part of a longitudinal surveillance program, 35 members larger dynamic cohort 79 Gulf War I veterans exposed to depleted uranium (DU) during combat underwent clinical evaluation at the Baltimore Veterans Administration Medical Center. Health outcomes and biomonitoring results were obtained assess effects DU exposure determine need for additional medical intervention. Clinical included histories, physical examination, laboratory studies including biomarkers (U) exposure. Urine collections...

10.1080/15287394.2011.539138 article EN Journal of Toxicology and Environmental Health 2011-03-22

During the 1991 GulfWar, U.S. service members were exposed to depleted uranium (DU) through friendly-fire incidents involving DU munitions and vehicles protected by armor. Routes of exposure involved inhalation soluble insoluble oxide particles, wound contamination, retained embedded metal fragments that continue oxidize in situ release systemic circulation. A biennial health surveillance program established for this group Veterans Department Affairs has shown continuously elevated urine...

10.1097/hp.0b013e31827b1740 article EN Health Physics 2013-02-23

To determine whether there would be racial and ethnic disparities in meeting eligibility criteria for medication therapy management (MTM) services implemented 2006 Medicare beneficiaries.

10.1111/j.1475-6773.2010.01118.x article EN Health Services Research 2010-05-27

Background: Gene therapy, altering the genes inside human cells, has recently emerged as an alternative for preventing and treating disease. Concerns have been expressed about clinical value high cost of gene therapies. Objective: This study assessed characteristics trials, authorizations, prices therapies in United States European Union. Research Design: We collected regulatory information from Food Drug Administration (FDA) Medicines Agency (EMA) manufacturer-listed States, UK, Germany....

10.1097/mlr.0000000000001840 article EN Medical Care 2023-03-08

Background A small group of Gulf War I veterans wounded in depleted uranium (DU) friendly fire incidents have been monitored a clinical surveillance program at the Veterans Affairs Medical Center, Baltimore since 1994. Methods An in‐patient protocol was performed on 35 members cohort, including exposure monitoring for total and isotopic concentrations urine comprehensive assessment health outcomes. Results Although U continue to be elevated this group, illustrating on‐going situ mobilization...

10.1002/ajim.22435 article EN American Journal of Industrial Medicine 2015-04-24

10.1331/108658002763029535 article EN Journal of the American Pharmaceutical Association (1996) 2002-07-01

Abstract Purpose To evaluate differences in prescription medication adherence rates, as well influencing factors, rural and urban adults. Methods This is a retrospective analysis of the 2015 National Consumer Survey on Medication Experience Pharmacists' Role. A total 26,173 participants completed survey provided usable data. Participants using between 1 30 medications living more than 0 miles up to 200 from their nearest pharmacy were selected for study, resulting 15,933 participants. Data...

10.1111/jrh.12291 article EN cc-by The Journal of Rural Health 2018-01-10
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