Eakkaluk Wongwad

ORCID: 0000-0003-4538-0441
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Advancements in Transdermal Drug Delivery
  • Wood and Agarwood Research
  • Tea Polyphenols and Effects
  • Natural product bioactivities and synthesis
  • Ginger and Zingiberaceae research
  • Phytochemicals and Antioxidant Activities
  • Pneumonia and Respiratory Infections
  • Dermatology and Skin Diseases
  • Natural Compound Pharmacology Studies
  • Identification and Quantification in Food
  • Biological and pharmacological studies of plants
  • Medicinal Plants and Neuroprotection
  • Phytochemistry Medicinal Plant Applications
  • Andrographolide Research and Applications
  • Plant Toxicity and Pharmacological Properties
  • Neurological Disease Mechanisms and Treatments
  • Bioactive Compounds and Antitumor Agents
  • Microbial Metabolism and Applications
  • Bioactive natural compounds
  • Phytochemistry and Biological Activities
  • Mangiferin and Mango Extracts
  • Ginseng Biological Effects and Applications
  • Hibiscus Plant Research Studies
  • Anorectal Disease Treatments and Outcomes

University of Phayao
2022-2025

Naresuan University
2018-2022

The leaf extract of Tectona grandis L.f. has shown potential as a 5α-reductase inhibitor, with two bioactive markers, namely (+)-eperua-8,13-dien-15-oic acid (1) and (+)-eperua-7,13-dien-15-oic (2), used for standardization. purpose this research was to investigate the in vitro skin penetration behavior 1 2 T. ethanolic solution ready-to-use propylene glycol (PG), secondly, determine their physicochemical properties, including partition coefficients solubility. appropriate vehicle study...

10.3390/molecules30051151 article EN cc-by Molecules 2025-03-04

Peristrophe bivalvis (L.) Merr. (Acanthaceae family) has traditionally been used as a natural food colorant and in the treatment of various diseases. However, its biological activities—particularly anti-glycation anti-lipid peroxidation properties—as well development novel nanoemulsions incorporating crude P. leaf extracts for cosmetic applications, have not yet reported. The aim this study was to explore potential an active ingredient nanocosmetics. Various solvents, including deionized...

10.3390/cosmetics12030092 article EN cc-by Cosmetics 2025-05-02

A new oxidized heptene, 7-benzoyloxy-4-hydroxy-1-ethoxy-2E,4Z-heptadiene-1,6-dione, namely siamheptene (1), together with eight known compounds (2-9), were isolated from the leaves of Uvaria siamensis. Their structures elucidated by detailed analysis spectroscopic (IR, 1D and 2D NMR) mass spectrometric data. Compound 9 is reported for first time genus. Siamheptene was evaluated cytotoxicity against HeLa (cervical cancer cells), A549 (lung Vero cells using MTT assay screened antibacterial...

10.1002/cbdv.202400319 article EN Chemistry & Biodiversity 2024-03-01

Dendrobium sulcatum Lindl or “Ueang Jampa-Nan” (Orchidaceae family) is widely dis-tributed in Thailand and Laos. It classified the genus Dendrobium, which used both traditional Chinese medicine Ayurvedic for health enhancement anti-aging. The purpose of this study was to investigate phytochemical constituents bioefficacy stems, leaves flowers from D. cosmetic cosmeceutical applications. Phenolic flavonoid contents were tested evaluation. antioxidant (DPPH, FRAP ABTS assays), anti-lipid...

10.3390/cosmetics10020043 article EN cc-by Cosmetics 2023-03-01

The leaves of Aquilaria spp. promote "physiological balance", and are "cardiotonic provide blood nourishment". In Asia, these increasingly consumed as tea claimed to benefits cardiovascular function, albeit without any scientific proof. Therefore, this study sought evaluate the action crassna leaf aqueous extract (AE) on vascular function smooth muscle cytotoxicity. AE a main constituent, mangiferin were investigated for their vasorelaxation rat mesenteric arteries aortae in vitro. Acute...

10.1016/j.jtcme.2018.09.002 article EN cc-by-nc-nd Journal of Traditional and Complementary Medicine 2018-09-12

Tectona grandis has been reported for its composition of two 5α-reductase inhibitors, specifically (+)-eperua-8,13-dien-15-oic acid (1) and (+)-eperua-7,13-dien-15-oic (2). These compounds exhibit potential as markers, enabling the standardization leaf extracts during pre-formulation formulation development. This study examined effects solvent system, pH, temperature light on stability 1 2 in ethanolic extract PG with PEG-40 a solubilizer. The remaining amount at all test conditions was...

10.48048/tis.2024.7339 article EN cc-by-nc-nd Trends in Sciences 2024-02-01

Andrographis paniculata (Burm. F.) Nees is a medicinal plant previously reported with broad-spectrum antivirals but the mode of inhibition remains elusive. The objective this study was to identify most active fraction from A. ethanol extract (APE, APE-2A, APE-2B and APE-2C) dry powder (APSP) against influenza A (H3N2), representing RNA viruses, herpes simplex virus-1 (HSV-1), DNA viruses. results showed that fractions APSP, APE, APE-2B, APE-2C directly neutralized HSV-1 (H3N2) when incubated...

10.1038/s41598-023-46249-y article EN cc-by Scientific Reports 2023-11-13

Thermal degradation of verbascoside (VB) in Acanthus ebracteatus Vahl (AE) always affects its health benefit. Here the temperature effect on VB both AE extract and solid lipid nanoparticles (SLNs)-encapsulated was demonstrated using Arrhenius plot. The reaction rate constants were calculated for shelf life plotted to obtain pH–rate profiles. a first-order reaction. neutral alkaline solution faster than an acidic solution. extract-loaded SLNs more stable uncapped extract. 153 days with...

10.1021/acsmedchemlett.2c00145 article EN ACS Medicinal Chemistry Letters 2022-06-21

The aim of this study was to investigate the effects drying process preparations, solvent type, and different species Prunus spp. (European, Japanese, cherry plums) on bioactive properties (antioxidant, anti‐lipid peroxidation, anti‐tyrosinase, anti‐inflammatory activities) rutin content. Leaves fresh fruits plums were dried using a cold (vacuum freeze dryer at −105 ± 5°C) hot (hot air oven 50 0.5°C). plant material then extracted ethanol propylene glycol obtain ethanolic crude extracts...

10.1155/2024/9999731 article EN cc-by International Journal of Food Science 2024-01-01

The health benefits of the Aquilaria crassna Pierre ex Lecomte leaf extract (AE) make it very useful as an ingredient in food and pharmaceutical products. Iriflophenone 3,5-C-β-d-diglucoside (1), iriflophenone 3-C-β-d-glucoside (2) mangiferin (3) are bioactive compounds AE. We assessed stability AE by investigating thermal degradation kinetics shelf-life (t90%) 1, 2 3 using Arrhenius plot models studied their pH-rate profiles. results demonstrate that 1 were degraded, following a first-order...

10.3390/molecules25214898 article EN cc-by Molecules 2020-10-23
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