A5061493455- Cell Image Analysis Techniques
- Single-cell and spatial transcriptomics
- Retinal Development and Disorders
- Stress Responses and Cortisol
- Molecular Biology Techniques and Applications
- Hormonal Regulation and Hypertension
- Veterinary Oncology Research
- Gender Diversity and Inequality
- Rabies epidemiology and control
- AI in cancer detection
- Adrenal Hormones and Disorders
- Retinal Imaging and Analysis
- Pluripotent Stem Cells Research
- Museums and Cultural Heritage
- Retinal Diseases and Treatments
- CRISPR and Genetic Engineering
- Innovative Human-Technology Interaction
- Neurobiology of Language and Bilingualism
- Human-Animal Interaction Studies
- Spatial Cognition and Navigation
New York Stem Cell Foundation
2020-2024
The University of Melbourne
2022-2023
Monash University
2022
Australian Regenerative Medicine Institute
2022
Drug discovery for diseases such as Parkinson's disease are impeded by the lack of screenable cellular phenotypes. We present an unbiased phenotypic profiling platform that combines automated cell culture, high-content imaging, Cell Painting, and deep learning. applied this to primary fibroblasts from 91 patients matched healthy controls, creating largest publicly available Painting image dataset date at 48 terabytes. use fixed weights a convolutional neural network trained on ImageNet...
Abstract Post-traumatic stress disorder (PTSD) can develop following severe trauma, but the extent to which genetic and environmental risk factors contribute individual clinical outcomes is unknown. Here, we compared transcriptional responses hydrocortisone exposure in human induced pluripotent stem cell (hiPSC)-derived glutamatergic neurons peripheral blood mononuclear cells (PBMCs) from combat veterans with PTSD ( n = 19 hiPSC 20 PBMC donors) controls donors). In only, observed...
Drug discovery for diseases such as Parkinson’s disease are impeded by the lack of screenable cellular phenotypes. We present an unbiased phenotypic profiling platform that combines automated cell culture, high-content imaging, Cell Painting, and deep learning. applied this to primary fibroblasts from 91 patients matched healthy controls, creating largest publicly available Painting image dataset date at 48 terabytes. use fixed weights a convolutional neural network trained on ImageNet...
The COVID-19 pandemic has been identified as a cause of sudden increase in puppy acquisition from breeders and shelters. During lockdown, opportunities to expose developing puppies variety novel humans animals were greatly diminished. A visit the veterinarian for vaccinations represented one few essential points contact. This article discusses possible interventions suggestions veterinary technician could make new owners their chances providing adequate socialization.
Age-Related Macular Degeneration (AMD) is a highly prevalent form of retinal disease amongst Western communities over 50 years age. A hallmark AMD pathogenesis the accumulation drusen underneath pigment epithelium (RPE), biological process also observable in vitro. The has been shown to predict progression advanced AMD, making accurate characterisation vitro models valuable modelling and drug development. More recently deposits above RPE subretinal space, called reticular pseudodrusen (RPD)...
In a world where stillness and silence are increasingly hard to come by, museums can provide space for slowness, reflection contemplation that contributes wellbeing as well inclusion of communities. This paper maps my current-ongoing PhD research into the benefits slow approach designing museum experiences, how this larger project making Bendigo Art Gallery more inclusive blind low vision (BLV) visitors. It guides reader through metaphorical visit, exhibition subject. The is invited engage...