A5018925788- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Aortic aneurysm repair treatments
- Mesenchymal stem cell research
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Tissue Engineering and Regenerative Medicine
- Cardiac Arrest and Resuscitation
- Cardiac Ischemia and Reperfusion
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Hip and Femur Fractures
- Electrospun Nanofibers in Biomedical Applications
- Anesthesia and Neurotoxicity Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Issues in Pregnancy
- Surgical Simulation and Training
- Infectious Aortic and Vascular Conditions
- Atrial Fibrillation Management and Outcomes
- Cardiac Health and Mental Health
- Coronary Artery Anomalies
- Congenital heart defects research
Health Sciences North
2019-2025
NOSM University
2020-2025
Science North
2019-2020
Western University
2020
University of Ottawa
2020
Ottawa Hospital
2020
University of Sudbury
2020
Sudbury Regional Hospital
2009
McGill University Health Centre
2000-2004
Montreal Children's Hospital
2004
Contemporary outcomes after surgical management of thoracic aortic disease have improved; however, the impact sex-related differences is poorly understood.A total 1653 patients (498 [30.1%] female) underwent surgery with hypothermic circulatory arrest between 2002 and 2017 in 10 institutions Canadian Thoracic Aortic Collaborative. Outcomes interest were in-hospital death, stroke, a modified Society Surgeons-defined composite for mortality or major morbidity (stroke, renal failure, deep...
Marrow stromal cells (MSCs) contain multipotent cells, which may participate in the repair of damaged organs. We tested hypothesis that MSCs are recruited to heart upon myocardial infarction (MI), and play pathophysiological roles healing adaptation process.Donor from isogenic Lewis rats were harvested, multiplied labeled with Lac Z reporter gene. Ten million injected intravenously into recipient (n=30). One week later, 10 killed examine distribution MSCs. Other underwent either coronary...
KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department.[1][1] It clinical spectrum diagnoses including dissection, intramural hematoma and penetrating atherosclerotic ulcer at
Abstract OBJECTIVES The aim of this study was to investigate the impact various brain perfusion techniques and nadir temperature cooling strategies on outcomes after aortic arch repair in a contemporary, multicentre cohort. METHODS A total 2520 patients underwent with hypothermic circulatory arrest (HCA) between 2002 2018 11 centres Canadian Thoracic Aortic Collaborative. Primary included mortality; stroke; composite mortality or Society Surgeons-defined (STS-COMP) end point for major...
To explore evolving surgical techniques and outcomes for aortic arch surgery. A total of 2435 consecutive patients underwent repair with hypothermic circulatory arrest between 2008 2018 in 12 institutions across Canada. Trends patient characteristics, techniques, in-hospital outcomes, including major morbidity or mortality, were examined. From to 2018, the age (62.3 ± 13.2 years) proportion women (30.2%) undergoing surgery did not change significantly. Aortic diameters at operation decreased...
Re-operative mitral valve surgery in patients with poor ventricular function can be challenging especially the presence of patent bypass grafts. We report case 11 severe ischemic cardiomyopathy who underwent reoperative repair through a limited right thoracotomy approach, on non-fibrillating beating heart. All had their valves successfully repaired no operative mortality and minimal morbidity. The technical aspects procedure are discussed, pertinent literature reviewed.
There is a very limited published material about experience with long-term pediatric mechanical circulatory support as bridge to heart transplant. We report on 2-year-old, 12 kg boy admitted 2-week history of low-grade fever, ear pain, pulmonary edema, and congestive failure. Trans-thoracic echocardiography confirmed severe myocardial dysfunction left ventricular ejection fraction 0.20 percentage shortening 13. After 2 days ventilatory inotropic support, the patient continued deteriorate...
Despite advancements in critical care and coronary revascularization, cardiogenic shock (CS) outcomes remain poor. Implementing a team use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) have been associated with improved CS outcomes, but its feasibility remote rural areas remains unknown.
Data are limited on long-term outcomes in patients who have undergone a reoperation following failure of stentless aortic valve.Between 2006 and 2016, retrospective analysis was performed 24 underwent open valve replacement surgery for failed prosthesis at Health Sciences North, Sudbury, Ontario, Canada. The primary outcome low mortality rate from cardiac-related deaths after 5 years.All insertion Medtronic Freestyle bioprosthesis (Minneapolis, MN) implanted using the modified subcoronary...