- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Cardiac Ischemia and Reperfusion
- Mechanical Circulatory Support Devices
- Mesenchymal stem cell research
- Transplantation: Methods and Outcomes
- Aortic aneurysm repair treatments
- Tissue Engineering and Regenerative Medicine
- Cardiovascular Function and Risk Factors
- Organ Transplantation Techniques and Outcomes
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Natural Compounds in Disease Treatment
- Congenital Heart Disease Studies
- Cerebrovascular and Carotid Artery Diseases
- ATP Synthase and ATPases Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrest and Resuscitation
- Nitric Oxide and Endothelin Effects
Centre Hospitalier de l’Université de Montréal
2016-2025
Université de Montréal
2016-2025
Toronto Public Health
2017-2021
Montreal Heart Institute
2005-2020
Vanderbilt University Medical Center
2020
Cambridgeshire Community Services NHS Trust
2019
Clinical Research Management
2019
Society of Interventional Radiology
2019
Centre Hospitalier Universitaire de Liège
2018
McGill University Health Centre
2016
Contemporary outcomes after surgical management of thoracic aortic disease have improved; however, the impact sex-related differences is poorly understood.A total 1653 patients (498 [30.1%] female) underwent surgery with hypothermic circulatory arrest between 2002 and 2017 in 10 institutions Canadian Thoracic Aortic Collaborative. Outcomes interest were in-hospital death, stroke, a modified Society Surgeons-defined composite for mortality or major morbidity (stroke, renal failure, deep...
Background Health inequalities exist for many disorders, but the contribution of deprivation to prevalence and outcome depressive symptoms in primary care populations has been infrequently studied. Aims To examine influence Jarman under-privileged area (UPA) scores on general practice patients. Method 18 414 patients attending 55 representative practices completed Hospital Anxiety Depression Scale a questionnaire employment status. Outcome those screening positive was assessed at 6 weeks...
Principal limitation of cell therapy is loss after transplantation because the interplay between ischemia, inflammation, and apoptosis. We investigated mechanism preconditioning mesenchymal stem cells (MSCs) with oxytocin (OT), which has been proposed as a novel strategy for enhancing therapeutic potential these in ischemic heart. In this study, we demonstrate that rat MSCs express binding sites OT receptor transcript protein detected by RT-PCR immunofluorescence, respectively. response to...
<h3>Importance</h3> The relative safety and patency of skeletonized vs pedicled internal mammary artery grafts in patients undergoing coronary bypass graft (CABG) surgery are unknown. <h3>Objective</h3> To investigate the association harvesting with clinical outcomes 1 year after CABG surgery. <h3>Design, Setting, Participants</h3> This study was a post hoc analysis multicenter, randomized, double-blind, placebo-controlled Cardiovascular Outcomes for People Using Anticoagulation Strategies...
Celastrol, a triterpene from plants, has been used in traditional oriental medicine to treat various diseases. Here, we investigated the cardioprotective effects of celastrol against ischaemia.Protective pathways induced by were hypoxic cultures H9c2 rat cardiomyoblasts and model myocardial infarction, assessed with echocardiographic histological analysis.In cells, triggered reactive oxygen species (ROS) formation within minutes, nuclear translocation transcription factor heat shock 1 (HSF1)...
Discrepancies in body fluid estimates between segmental bioimpedance spectroscopy (SBIS) and gold-standard methods may be due to the use of a uniform value tissue resistivity compute extracellular volume (ECV) intracellular (ICV). also arise from exclusion volumes hands, feet, neck, head measurements electrode positions. The aim this study was define specific various segments those values for computation ECV ICV along with correction unmeasured volumes. Twenty-nine maintenance hemodialysis...
Bone marrow stem cell therapy has emerged as a promising approach to improve healing of the infarcted myocardium. Despite initial excitement, recent clinical trials using non-homogenous cells preparations showed variable and mixed results. Selected CD133 + hematopoietic are candidate with high potential. Herein, we report one-year safety analysis on 20 patients enrolled in COMPARE-AMI trial, first double-blind randomized controlled trial comparing safety, efficacy, functional effect...