A5052115370- Empathy and Medical Education
- Genetic and rare skin diseases.
- Medical and Biological Sciences
- Cutaneous Melanoma Detection and Management
- Dermatological and Skeletal Disorders
- Comics and Graphic Narratives
- Cancer and Skin Lesions
- Invertebrate Immune Response Mechanisms
- Developmental Biology and Gene Regulation
- Genetic and Kidney Cyst Diseases
- Health and Medical Research Impacts
- Histiocytic Disorders and Treatments
- Immune cells in cancer
- Autoimmune Bullous Skin Diseases
- Academic Writing and Publishing
- Global Cancer Incidence and Screening
- Neurology and Historical Studies
- Marine Biology and Environmental Chemistry
- Skin Diseases and Diabetes
- Science Education and Perceptions
- Ethics in Clinical Research
- Cell Image Analysis Techniques
- Digital Imaging in Medicine
- History of Medical Practice
- Nonmelanoma Skin Cancer Studies
University of California, Davis
2021-2024
Cambridge Health Alliance
2021
Cambridge Hospital
2021
Harvard University
2021
Stanford University
2017-2019
Stanford Medicine
2019
Artistic Realization Technologies
2018
University of Manchester
2017
Henry Royce Institute
2017
Melanoma clinical outcomes emerge from incompletely understood genetic mechanisms operating within the tumor and its microenvironment. Here, we used single-cell RNA-based spatial molecular imaging (RNA-SMI) in patient-derived archival tumors to reveal clinically relevant markers of malignancy progression prognosis. We examined gene expression 203,472 cells inside benign malignant melanocytic neoplasms, including nevi primary invasive metastatic melanomas. Algorithmic cell clustering paired...
Abstract Background A eukaryotic cell's primary cilium (PC) is critical for cell signaling, migration and homeostasis. Primary dysfunction has been demonstrated in several malignancies, but whether cilia loss occurs acral melanoma remained unknown. To address this, we examined the ciliation index (% melanocytes containing a PC) of patient‐derived, biopsy‐proven compared these to benign nevi. Methods We generated pilot initiative study that included six melanomas seven nevi derived from foot....
Sebaceous carcinoma (SBC) is a rare malignant tumour of sebocytes that commonly presents as nodule on the eyelid. It considered an aggressive skin cancer has potential to metastasise; therefore, early diagnosis critical for survival. The histopathology SBC can mimic other neoplasms, including basal cell (BCC) and squamous carcinoma, making challenging in subset cases.1 Therefore, finding effective specific marker SBCs aid earlier more accurate diagnosis. Normal sebaceous glands stain...
When I began medical school, was surprised by the frequent use of mnemonics as memory tools in classroom and clinic. intrigued idea that these are passed on, formally informally, from one generation students to next a rite passage. However, tickled unique sometimes ridiculous wording certain mnemonics, like “SAD PUCKER”; “canned soup, really good cans”; “a lady between two majors”; “to Zanzibar motor car, please!” wonder if could also serve inspiration for whimsical illustration, color...
Mnemonics help memorization via cognitive mechanisms that are incompletely understood; their use within medical culture is prolific and can be traced back hundreds to thousands of years.1,2 Although most mnemonics utilize letter- or word-based creative modalities, (eg, acronyms, initialisms, rhyme, play on words), other visual rely physical props, including the human body.3 Here, we appreciate a mnemonic uses hand represent spinal nerve contributions brachial plexus, which has clinical...
In 2016, I undertook a project to illustrate 16 anatomic mnemonics, selecting those that both were educationally functional and used phrases invoked in me special meaning, idea, or image. knew at once the mnemonic “A Lady Between Two Majors” fit these self-imposed criteria. First, let us consider meaning behind mnemonic. It pertains muscles from chest (pectoralis major), back (latissimus dorsi), scapula (teres major) attach bicipital groove of humerus specific arrangement facilitate movement...
In 2016, I undertook a project to illustrate 16 anatomic mnemonics, selecting those that were educationally functional and used phrases invoked in me special meaning or image. knew immediately the mnemonic “to Zanzibar by motor car, please!” fit these self-imposed criteria. First, let us consider anatomical behind mnemonic, which pertains branches of facial nerve (CN VII). Recall innervates muscles face, including control blinking smiling. After leaving skull, into Temporal, Zygomatic,...
This graphic narrative is a fictional case report illustrated using paint pens and histological micrographs collaged with Adobe Illustrator. The story of Mr P his physician recapitulates an ethical dilemma presented by cancer screening: screening can save lives
Myxedema is a rare, cutaneous complication of autoimmune thyroid diseases that most often affects the anterior shins. Herein, we report patient with history Graves disease and Hashimoto thyroiditis who presented boggy, alopecic patches associated scalp pruritus. Punch biopsies from these lesions showed increased interstitial mucin in reticular dermis, consistent localized myxedema. This showcases rare presentation myxedema scalp, highlighting diverse manifestations diseases.
ABSTRACT Fertilisation triggers embryonic development culminating with the activation of a number highly co-ordinated and evolutionarily conserved signalling pathways, which induce pattern mesoderm developing embryo. Previous studies in invertebrates have shown that hydrogen peroxide (H 2 O ), reactive oxygen species (ROS), can act as molecule for axis specification during early development. Using HyPer transgenic Xenopus laevis line expresses H -sensitive fluorescent protein sensor...
The Precision Portrait is a mixed-media portrait illustrating the future of precision medicine and its ethical challenges.
This Arts and Medicine essay describes an art installation that commemorates the bicentennial of Mary Shelley’s Frankenstein with clinical elements illustrate relevance novel’s story themes to medical research practice.
This Arts and Medicine feature explains how Japanese language medical mnemonics are constructed features a 16-panel mixed-media art installation featuring elements of for vaccines, relative bradycardia, subclavian artery anatomy.