Paravertebral block (PVB) is commonly used for analgesia postoperatively while rarely as anesthesia during surgical stabilization rib fractures. This study aimed to explore the feasibility and safety of PVB alone patients with multiple fractures (MRF) under conscious state. prospective single-arm pilot was conducted in MRF who schedule using Shanghai Sixth People's Hospital Affiliated Jiao Tong University School Medicine between September 2019 2020. The outcomes were vital signs,...

Background: To assess the feasibility and perioperative outcomes of single-port (SP) multi-port (MP) approaches for video-assisted thoracoscopic surgery (VATS) lobectomy anatomical segmentectomy. Methods: Retrospective data from 458 patients who received VATS or segmentectomy at Shanghai Chest Hospital, Korea University Guro Affiliated Hospital National Taiwan University, Hong Kong Queen Mary Shenzhen were collected. Patients divided into SP group MP according to surgical approach....

With the popularization of minimal invasive surgery, video-assisted thoracoscopic surgery (VATS) is gradually replacing conventional thoracotomy for lung cancer and even used osteosarcoma patients with pulmonary metastasis. In this study, we characterized need open by comparing computer tomography (CT) diagnosis postoperative pathology metastases osteosarcoma.A retrospective analysis was carried out on underwent metastatic admitted to our hospital between January 2008 July 2018. The numbers...

Non-small cell lung cancer (NSCLC) is a deadly type worldwide and the main sub-type of cancer. Cancer susceptibility candidate-9 (CASC9) was reported to be key player in progression. However, its function underlying mechanism NSCLC remain unclear.Expression level CASC9 tissues cells measured with RT-qPCR. Biological roles were analyzed series vitro experiments. Potential mechanisms by predicting validating possible targets NSCLC.In this study, we found expression upregulated lines. High...

Vascular endothelial growth factor-A, an angiogenesis stimulator expressed on both tumor and malignant T cells, is involved in progression T-leukemia/lymphoma. Here, we assessed the impact of therapeutic vascular factor-A blockade tumor-endothelial cell interaction progression. In a murine xenograft T-leukemia/lymphoma model, combined bevacizumab (monoclonal antibody against factor-A) with doxorubicin, compared doxorubicin alone, significantly delayed induced prevalence apoptosis over...

Background: Video-assisted thoracoscopic surgery (VATS) has been increasingly used in the treatment of lung cancers. But it is still unclear whether mediastinal lymph node dissection (LND) under VATS safe and feasible. The aim this study to figure out LND by

Background The safety, feasibility, and prognosis of sleeve lobectomy by minimally invasive surgery (MIS) remain to be validated. purpose this study was investigate outcomes in real-world patients receiving a balanced large cohort. Methods Between January 2013 December 2018, 578 consecutive undergoing resection at high-volume center were retrospectively analyzed. Surgical oncologic compared between MIS thoracotomy after propensity-score matching (PSM). Results increasingly used as time-trend...

Thymoma is an epithelial neoplasm of the thymus. It commonly lies in anterior mediastinum and represents 20-30% mediastinal tumours adults. In this report we present a case giant thymoma locating anterior-inferior mediastinum. A 46-year-old male came to our institute with slight pectoralgia dyspnea. Chest CT shows tumor measuring 19 cm × 16 15 left thoracic cavity. After careful examination, performed surgery. At surgery, found was adherent upper lobe lung, pleura, parietal pleural. The...

Abstract Background No consensus was reached on the surgical procedure for patients with stage I non-small-cell lung cancer (NSCLC) ≤ 2 cm. The aim of this study is to investigate appropriate NSCLC ≤2 Methods Patients cm received wedge resection, segmentectomy, lobectomy between January 2004 and December 2015 were identified using Surveillance, Epidemiology, End Results (SEER) database. Data stratified by age, gender, race, side, location, grade, histology, extent lymphadenectomy. Overall...

Phrenic nerve injury (PNI) during lung cancer surgery, without apparent section or damage, is still not well-studied. The aim of our study to find an easy and objective way evaluate a significant diaphragm elevation (SDE) suggestive inadvertent PNI its incidence impact on patients undergone video-assisted thoracoscopic surgery (VATS) lobectomy.Extent was first examined chest X-ray in cohort with invasive thymoma whom phrenic intentionally transected. result then used as the criterion...

Abstract Background Nonintubated video-assisted thoracoscopic surgery has been widely reported in the past decade, while nonintubated chest wall stabilization not previously. The aim of this study was to evaluate safety and feasibility minimally invasive patients with multiple rib fractures. Methods We conducted a prospective, single-arm, observational study. In prospective study, 20 consecutive fractures were treated using stabilization. Results Minimally mostly performed for lateral ( n =...

A 16-year-old boy suffered from headaches and dizziness for 2 years. He was found to have remarkably elevated blood pressure (BP) of 180/110 mmHg. Laboratory findings showed a low level serum potassium markedly increased plasma renin activity. solid mass at the periphery right kidney double inferior vena cava (IVC) were detected by abdominal computer tomography (CT). Right partial nephrectomy via laparoscopy performed on patient. The histologic electron microscopic comfirmed diagnosis...

Abstract: Primary extragenital choriocarcinoma is a highly malignant tumor and usually occurs in the midline of body, such as mediastinum, retroperitoneum, pineal gland middle part brain. In this report we present case primary located posterior mediastinum. A 40-year-old man was admitted to hospital with severe chest wall pain for 2 months. Enhanced computed tomography (CT) showed mass soft tissue measuring 5.2 cm × 4.5 CT-guided percutaneous fine needle aspiration (FNA) biopsy performed...

Thymic tumors usually present with adjacent organ invasion or pleural dissemination, but very few studies have reported on occult dissemination detected intraoperatively. This study aimed to investigate the risk factors that can predict preoperatively.Consecutive patients thymic who underwent surgery from January 2010 2017 were reviewed. Only without preoperatively included in this study. Demographic, clinical, pathological, and survival data collected for statistical analysis. Further...

Abstract Background Isolated malignant pulmonary nodules were frequently seen in patients with breast cancer. These metastasis from the cancer or new primary lung The role of surgery for such remains unclear. Methods A total 90 who underwent solitary between January 2010 and April 2018 after curative operation reviewed. Results pathologic diagnoses revealed 63 (PLC) 27 metastatic (MBC), which divided into two groups. All female a mean age 55.08 ± 9.84 years (range 31–75). Age differences...

It has been proven that chemotherapy failure caused by multidrug resistance in lung tumor cells is the main cause for patient's survival rate. The aim of this study to establish a cell line human adenocarcinoma and mechanism resistance.Human A549 was induced A549/cDDP intermittent administration high dose cisplatin (cDDP). detected using MTT assay. levels expression MDR-1 gene-coded P-glycoportein (P-gp), resistance-associated protein (MRP), GSH/GST were examined flow cytometric MDR MRP gene...

Minimally invasive esophagectomy has been gaining increasing interest in management of early stage esophageal cancers. Similar oncological principles including radical removal the tumor as well systemic lymph node dissection should be observed, regardless surgical approach. Improvement techniques would help achieve comparable outcomes while patients benefit from minimally This video introduces an antegrade which is alternative to traditional retrograde for squamous cell carcinoma thoracic...

<title>Abstract</title> Aims There were some studies reported inconsistent results on the associations between fetal sex and maternal metabolism. This study aimed to examine effect of glucose lipid metabolism perinatal outcomes in women with gestational diabetes mellitus (GDM) during pregnancy Chinese population. Methods was a retrospective cohort including 134 diagnosed as GDM. All them accepted 100g oral tolerance test(OGTT) 26–29 week because positive 50g challenge test(GCT) then had...