Yan Ju

ORCID: 0000-0003-4588-0710
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Research Areas
  • AI in cancer detection
  • Natural product bioactivities and synthesis
  • Digital Radiography and Breast Imaging
  • Congenital heart defects research
  • Congenital Heart Disease Studies
  • Global Cancer Incidence and Screening
  • Molecular Biology Techniques and Applications
  • Cervical Cancer and HPV Research
  • Lung Cancer Treatments and Mutations
  • Congenital Diaphragmatic Hernia Studies
  • Phytochemistry and Biological Activities
  • Plant biochemistry and biosynthesis
  • Cancer, Hypoxia, and Metabolism
  • Cardiomyopathy and Myosin Studies
  • Medicinal Plant Pharmacodynamics Research
  • Pharmacological Effects of Natural Compounds
  • Cardiovascular Function and Risk Factors
  • Animal Virus Infections Studies
  • Pancreatic and Hepatic Oncology Research
  • Cancer Treatment and Pharmacology
  • Cancer-related molecular mechanisms research
  • Colorectal Cancer Surgical Treatments
  • Traditional Chinese Medicine Studies
  • Colorectal and Anal Carcinomas
  • Toxin Mechanisms and Immunotoxins

Xijing Hospital
2017-2025

Air Force Medical University
2016-2025

Shaanxi Provincial People's Hospital
2025

Chinese PLA General Hospital
2021-2024

Third Affiliated Hospital of Southern Medical University
2023-2024

St. Jude Children's Research Hospital
2024

Southern Medical University
2024

Maternal and Child Health Hospital of Sichuan Province
2024

Xinjiang Medical University
2015-2023

Shanxi Medical University
2023

Treatment of infected bone defects is a major clinical challenge; bioactive materials combining sufficient antimicrobial activity and favorable osteogenic ability are urgently needed. In this study, through facile one-pot hydrothermal reaction zinc acetate in the presence tannic acid (TA), with or without silver nitrate (AgNO3 ), used to synthesize TA nanoparticles (Ag NPs) bulk-modified oxide (ZnO) (ZnO-TA ZnO-TA-Ag), which further composited zein fabricate porous microparticulate scaffolds...

10.1002/adhm.202300303 article EN Advanced Healthcare Materials 2023-03-25

Abstract Background Locally harvested wild edible plants (WEPs) provide food as well cash income for indigenous people and are of great importance in ensuring global security. Some also play a significant role maintaining the productivity stability traditional agro-ecosystems. Shangri-la region Yunnan Province, SW China, is regarded biodiversity hotspot. People living there have accumulated knowledge about plants. However, with economic development, WEPs threatened associated danger being...

10.1186/1746-4269-9-28 article EN cc-by Journal of Ethnobiology and Ethnomedicine 2013-04-19

Background Computer-aided detection (CAD) systems may be used to help radiologists interpret automated breast (AB) US images. However, the optimal use of CAD with AB has, knowledge authors, not been determined. Purpose To compare performance and reading time different readers by using system detect cancer in modes. Materials Methods In this retrospective study, 1485 images (282 malignant lesions, 695 benign 508 healthy) 1452 women (mean age, 43.7 years; age range, 19–82 years) including 529...

10.1148/radiol.2019181816 article EN Radiology 2019-06-18

Ecdysterone (Ecd), an active ingredient in trianthema, has a strong anti-inflammatory effect. This study aimed to explore the potential mechanism by which Ecd improves atherosclerosis (AS). Here, we systematically investigated of human umbilical vein endothelial cells (HUVECs) treated with oxidised low-density lipoprotein (ox-LDL). In ox-LDL-treated HUVECs, promoted HUVEC viability as well inhibited ferroptosis and secretion inflammatory factors (TNF-α, IL-6 IL-1β). addition, expression...

10.1111/jcmm.70446 article EN cc-by Journal of Cellular and Molecular Medicine 2025-03-01

Breast cancer (BC) is a with high incidence and mortality of female, threatening women's physical mental health. Achyranthes bidentata Blume, traditional Chinese medicine, has been popular in folk due to its effective pharmacology activities including anti-inflammatory anti-tumour effects. In order identify the active ingredients from roots A. for treating breast cancer, separation guided by network analysis was employed which led isolation 7 triterpenoids 10 phytosterones. According vitro...

10.1080/14786419.2020.1805603 article EN Natural Product Research 2020-08-10

Rationale: Intravascular/intravenous leiomyomatosis (IVL) is a peculiar variant of uterine leiomyoma that classified as histologically benign smooth muscle tumor with biological behavior similar to malignant tumor. It characterized by the proliferation leiomyomas spreading along and extrauterine venous circulation. Patient concerns: Herein, we present 2 cases IVL who had completely different clinical manifestations stress need for constant vigilance diagnosis understanding heterogenicity....

10.1097/md.0000000000036887 article EN cc-by-nc Medicine 2024-01-12

Abstract The detection of high‐risk human papillomaviruses (HPVs) is crucial for early screening and preventing cervical cancer. However, the substantial workload in high‐level hospitals or limited resources primary‐level hinder widespread testing. To address this issue, we explored a sample‐to‐answer genotyping system assessed its performance by comparing it with traditional real‐time polymerase chain reaction (PCR) method conducted manually. Samples randomly selected from those undergoing...

10.1002/jmv.29496 article EN Journal of Medical Virology 2024-02-25

Induced pluripotent stem cells (iPSCs) harboring patient derived SAMD9 mutation offer a unique platform to study the multi-organ involvement observed in this rare disease, referred as myelodysplasia, infections, restriction of growth, adrenal hypoplasia, genital phenotypes, and enteropathy (MIRAGE) syndrome. The nature iPSCs allows vitro differentiation into various somatic cell types representing multiple organ systems affected SAMD9-mutated patients. Hence, paper, we present...

10.1016/j.scr.2024.103532 article EN cc-by-nc-nd Stem Cell Research 2024-08-12

BACKGROUND. China has faced barriers to implementation of a population-based mammographic screening program. Breast ultrasound provides an alternative modality mammography in low-resource settings. OBJECTIVE. The purpose this study was evaluate the performance automated breast (ABUS) with remote reading as primary for cancer. METHODS. This prospective enrolled asymptomatic women 35-69 years old from 46 community health centers across 18 provinces representing all six regions January 2021...

10.2214/ajr.24.31830 article EN American Journal of Roentgenology 2024-10-23

Ectopic pregnancy, in which the fertilized ovum implants on any tissue other than endometrium, is most common life-threatening emergency first trimester of pregnancy. The incidence ectopic pregnancy 0.25%-1.0% all pregnancies, and has increased greatly last few decades, from 4.5 per 1000 pregnancies 1970 to an estimated 19.7 1992.1 Generally more 95% gestations are tubal pregnancies; only 1.4% abdominal very rare cases retroperitoneal Our review literature showed that 10 have been reported...

10.1097/00029330-200807020-00016 article EN cc-by-nc-nd Chinese Medical Journal 2008-07-01

We investigated the pathogenesis of MYH7-V878A and CACNA1C-A1594V mutations in a Chinese family with hypertrophic cardiomyopathy.Clinical, electrocardiographic (ECG), echocardiographic, cardiac magnetic resonance (CMR) examinations members were followed by exon boarding intron analyses 96 genes proband using second-generation sequencing. confirmed bidirectional Sanger sequencing 300 healthy controls.We detected this family. The both showed inverted T-waves ST-segment depression ECG...

10.1159/000478900 article EN Cardiology 2017-01-01

The paper documents on the uses of traditional medicinal plants used for treating human ailments in three villages Ledong, a county inhabited by Li ethnic group southwest Hainan Province, China. Semi-structured interviews, key informant interviews and participatory observations were to collect ethnobotanical data from February March 2012 July 2013. collected was analyzed using descriptive statistics. Thirty native knowledgeable people interviewed. community 50 plant species 36 families...

10.5586/asbp.3485 article EN cc-by Acta Societatis Botanicorum Poloniae 2016-01-01

Lung cancer is a common malignant tumor that seriously threatens human health. It has become the top in terms of morbidity and mortality. In recent years, circRNA, special noncoding RNA molecule, attracted considerable interest. This study focused on role circRNA ANXA2 (circANXA2) lung molecular mechanism promotion. Real-time quantitative PCR (RT-PCR) was used detecting expression abundance circANXA2 different cells tissues. The subcellular localization detected through fluorescence situ...

10.1155/2021/4526609 article EN Journal of Oncology 2021-12-28

The long-term survival prognosis of patients with high-grade (Hunt-Hess grade IV-V or World Federation Neurosurgical Societies IV-V) aneurysmal subarachnoid hemorrhage (aSAH) is generally poor, and the association between endovascular treatment timing aSAH has not been explored in depth. This retrospective cohort study aimed to determine whether within 24 h associated a better prognosis.We retrospectively analyzed clinical data who were admitted our institution January 2018 2021. Modified...

10.3389/fneur.2022.963624 article EN cc-by Frontiers in Neurology 2022-08-12
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