Chao Sun

ORCID: 0009-0007-0830-151X
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About
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Research Areas
  • Cardiomyopathy and Myosin Studies
  • Peripheral Neuropathies and Disorders
  • Myasthenia Gravis and Thymoma
  • Cancer-related gene regulation
  • Phonocardiography and Auscultation Techniques
  • Ultrasound and Hyperthermia Applications
  • Fermentation and Sensory Analysis
  • Colorectal Cancer Treatments and Studies
  • Plant Gene Expression Analysis
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Gastrointestinal motility and disorders
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Horticultural and Viticultural Research
  • Cardiac Arrhythmias and Treatments
  • Botanical Studies and Applications
  • Cardiac Ischemia and Reperfusion
  • Vascular Malformations and Hemangiomas
  • Lymphatic Disorders and Treatments
  • Peptidase Inhibition and Analysis
  • Cancer Mechanisms and Therapy
  • Congenital heart defects research
  • Lignin and Wood Chemistry
  • Thyroid and Parathyroid Surgery
  • Quinazolinone synthesis and applications

Shaanxi Provincial People's Hospital
2023-2024

Shanxi Medical University
2023-2024

Northern Jiangsu People's Hospital
2021-2024

Shenyang Agricultural University
2022

Qingdao Agricultural University
2022

Second Xiangya Hospital of Central South University
2018

Central South University
2018

First Affiliated Hospital of Xi'an Jiaotong University
2017

Shihezi University
2014

Northwest A&F University
2013

Treatment of functional dyspepsia is difficult due to various pathophysiological factors. The proposed method transcutaneous auricular vagal nerve stimulation improves symptoms both and depression/anxiety, gastric functions (accommodation slow waves), possibly mediated via the enhancement efferent activity. This noninvasive easy-to-implement neuromodulation will be well received by patients healthcare providers.

10.1152/ajpgi.00426.2020 article EN AJP Gastrointestinal and Liver Physiology 2021-02-24

Surgical approach in the treatment of thymoma is varied. This retrospective study aimed to evaluate outcomes different surgical approaches thymoma. From January 2020 December 2023, a total 208 patients underwent thoracoscopic and were diagnosed with by postoperative pathological result our institution. We collected then analysed potential factors including general conditions, approaches, preoperative clinical symptoms, procedures, hospital stay, drainge, pain score, complications follow-up....

10.1186/s13019-024-03081-3 article EN cc-by-nc-nd Journal of Cardiothoracic Surgery 2024-10-07

We investigated the pathogenesis of MYH7-V878A and CACNA1C-A1594V mutations in a Chinese family with hypertrophic cardiomyopathy.Clinical, electrocardiographic (ECG), echocardiographic, cardiac magnetic resonance (CMR) examinations members were followed by exon boarding intron analyses 96 genes proband using second-generation sequencing. confirmed bidirectional Sanger sequencing 300 healthy controls.We detected this family. The both showed inverted T-waves ST-segment depression ECG...

10.1159/000478900 article EN Cardiology 2017-01-01

Evodiamine is the main active alkali of Wu Zhuyu, a widely distributed Chinese herb.It plays an important role in regulation body fat deposition.In this study, we aimed to investigate effect evodiamine administration on expression genes involved lipid metabolism liver and adipose tissue.Fasted mice were subcutaneously injected with (37°C, 20 mg/kg), core temperature change levels metabolismrelated evaluated at baseline, 0.5, 1, 2 h.We detected mRNA fatty acid synthesis enzyme (FAS),...

10.4238/2013.january.4.13 article EN Genetics and Molecular Research 2013-01-01

The hard-end is a disorder of pear fruit, however, the mechanisms underlying its development remain unknown. In this study, we found that fruit contained higher transcript abundance level ethylene-response factor 1b-like ( PpERF1b-like ) and released more ethylene compared to normal pear. ethephon treated flesh tissues accumulated lignin together with elevated expression . Overexpressing transiently in stably callus increased accumulation biosynthesis genes; opposite results were observed...

10.3389/fpls.2022.1087388 article EN cc-by Frontiers in Plant Science 2022-12-15

To explore the relationship between electrocardiographic (ECG) and genetic mutations of patients with hypertrophic cardiomyopathy (HCM), early ECG changes in HCM patients.Clinical, 12-lead echocardiographic examination as well examinations were made a three-generation Chinses pedigree 8 family members (4 males). The clinical characterization parameters analyzed their genotypes was explored.Four missense (MYH7-H1717Q, MYLK2-K324E, KCNQ1-R190W, TMEM70-I147T) detected this pedigree. proband...

10.3760/cma.j.issn.0253-3758.2016.01.011 article EN PubMed 2016-01-01

e23265 Background: BRAF mutations are frequently found in melanoma, non-small cell lung cancer (NSCLC), thyroid cancer, to a lesser degree other tumor types. These constantly activate the kinase domain and result MAPK pathway hyperactivation. Successful inhibition of this with BRAF/MEK inhibitors (BRAFi/MEKi) results clinically meaningful benefit for some patients. The RBAST study, assess efficacy survival outcomes inhibitor-based therapy were investigated patients solid tumors harboring...

10.1200/jco.2024.42.16_suppl.e23265 article EN Journal of Clinical Oncology 2024-06-01

Aim of review: The underlying mechanisms ischemic preconditioning (IPC) have been studied for many years, but not elucidated completely. available literatures indicate that endothelial derived neuregulin-1 (NRG-1) is involved in myocardial ischemia/reperfusion injury (IRI) and protects cardiomyocytes against H2O2-induced apoptosis by regulating endoplasmic reticulum stress (ERS). aim this review to provide the evidence NRG-1 maybe a crucial biomolecule mediating powerful cardioprotection...

10.24015/japm.2017.0008 article EN Journal of Anesthesia and Perioperative Medicine 2017-02-08

Abstract Crataegus bretschnesideri C. K. Schneid. originated in Northeast China, it has excellent characteristics of cold resistance and early maturity. However, the taxonomic status been controversial due to intra-specific hybridization apomixes. Comparative assessment phenotypic molecular evaluations used explore genetic diversity bretschneideri relative species. Qualitative quantitative traits species were evaluated. Genetic population structure several analyzed by thirteen reported five...

10.21203/rs.3.rs-1272845/v1 preprint EN cc-by Research Square (Research Square) 2022-02-01
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