Yasue Sakurada

ORCID: 0000-0003-4588-5888
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About
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Research Areas
  • Long-Term Effects of COVID-19
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • COVID-19 and Mental Health
  • COVID-19 Clinical Research Studies
  • Thermal Regulation in Medicine
  • SARS-CoV-2 and COVID-19 Research
  • Multiple Sclerosis Research Studies
  • Vestibular and auditory disorders
  • Infectious Encephalopathies and Encephalitis
  • Hematological disorders and diagnostics
  • Inflammasome and immune disorders
  • Stress Responses and Cortisol
  • SARS-CoV-2 detection and testing
  • Olfactory and Sensory Function Studies
  • Diabetic Foot Ulcer Assessment and Management
  • Dysphagia Assessment and Management
  • Animal Virus Infections Studies
  • Mitochondrial Function and Pathology
  • Immunotherapy and Immune Responses
  • Pharmacological Effects of Natural Compounds
  • Clinical Nutrition and Gastroenterology
  • Heart Rate Variability and Autonomic Control
  • High Altitude and Hypoxia
  • Peripheral Neuropathies and Disorders
  • Intensive Care Unit Cognitive Disorders

Okayama University
2021-2025

Mannari Hospital
2017

Symptoms of long COVID are complex and long-lasting, endocrine dysfunction might be involved in the underlying mechanisms. In this study, to clarify hormonal characteristics patients, laboratory data for patients who visited outpatient clinic were evaluated. A retrospective analysis was performed Okayama University Hospital during period from Feb 2021 Dec with focus on interrelationships between major symptoms data. Information obtained medical records 186 patients. The had various symptoms,...

10.1507/endocrj.ej22-0093 article EN Endocrine Journal 2022-01-01

Background and Objectives: COVID-19 can be serious not only in the acute phase but also after some patients develop ME/CFS. There have been few studies on with long COVID whom ME/CFS was diagnosed by physicians based standardized criteria examinations exclusion diagnosis subjective symptoms. The purpose of this study to elucidate detailed characteristics COVID. Materials Methods: A retrospective descriptive performed for who visited a aftercare clinic established Okayama University Hospital...

10.3390/medicina58070850 article EN cc-by Medicina 2022-06-25

The pathogenesis and prognosis of post COVID-19 condition have remained unclear. We set up an outpatient clinic specializing in long COVID February 2021 we been investigating condition. Based on the results our earlier study showing that “general fatigue” mimicking myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is most common symptom patients, a retrospective analysis was performed for 39 male patients whom serum free testosterone (FT) levels were measured out 61 who visited...

10.3390/jcm11071955 article EN Journal of Clinical Medicine 2022-03-31

Purpose To elucidate the impact of long COVID on menstruation and mental health, medical records patients with were evaluated.

10.1080/0167482x.2024.2305899 article EN cc-by Journal of Psychosomatic Obstetrics & Gynecology 2024-01-25

Introduction The long-term clinical course, prognosis, and optimal management of symptoms conditions after the acute phase coronavirus disease 2019 (COVID-19) remain to be elucidated. purpose this study was clarify characteristics patients referred a COVID-19 aftercare (CAC) clinic established at tertiary academic hospital in Japan. Methods This descriptive case series study. All who visited CAC between February 15 September 17 2021 were included. Patients' background, chief complaints,...

10.7759/cureus.18568 article EN Cureus 2021-10-07

Various symptoms persist even after the acute in about one third of patients with COVID-19. In February 2021, we established an outpatient clinic a university hospital for long COVID and started medical treatment sequelae that persisted month or more infection.To determine key factors affect onset clinical course sequelae, retrospective analysis was performed at Okayama University Hospital (Japan) between July 2021. We focused on changes numbers background during three-month period from...

10.3390/jcm11051309 article EN Journal of Clinical Medicine 2022-02-27

Background and Objectives: Changes in post COVID-19 condition (PCC) characteristics caused by viral variants have yet to be clarified. We aimed characterize the differences between clinical backgrounds manifestations long COVID patients who were infected with Delta variant those Omicron variants. Materials Methods: This study was a single-center retrospective observational for visited our aftercare outpatient clinic (CAC) established Okayama University Hospital (Japan) during period from 15...

10.3390/medicina58101393 article EN cc-by Medicina 2022-10-05

Objectives: Evidence for the usefulness of biomarkers that aid in diagnosis, assessment severity, and prediction prognosis patients with long COVID is limited. The aim this study was to clarify characteristics brain natriuretic peptide (BNP) COVID. Methods: We conducted a retrospective observational who visited COVID-19 aftercare outpatient clinic at Okayama University Hospital from February 2021 April 2024. Results: A total 428 were enrolled study, divided into group normal BNP (n = 314,...

10.3390/jcm14030817 article EN Journal of Clinical Medicine 2025-01-26

Background: After the start of COVID-19 pandemic, general fatigue in patients with long COVID and post-COVID-19 conditions (PCC) became a medical issue. Although there is lack evidence-based treatments, Kampo medicine (traditional Japanese medicine) has gained attention Japan. At an outpatient clinic Japan specializing COVID, 24% all prescriptions were medicines, 72% hochuekkito. However, been no prospective, quantitative study on course PCC who prescribed The aim this was to clarify those...

10.3390/jcm14041391 article EN Journal of Clinical Medicine 2025-02-19

Background: During the coronavirus disease 2019 (COVID-19) pandemic, people in Japan were urged to stay at home as much possible, and this resulted significant changes lifestyle behavior. The new included factors affecting both energy intake consumption, it is now thought that weight gain during lockdown was result of complex effects. aim study determine relationships among habits, laboratory data, body using medical check-up data. Methods: A total 3789 individuals who had undergone...

10.3390/jcm14072242 article EN Journal of Clinical Medicine 2025-03-25

Objectives: The present study aimed to elucidate the characteristics of long COVID patients with headaches. Methods: A single-center retrospective observational was performed for outpatients who visited our hospital from 12 February 2021 30 November 2022. Results: total 482 patients, after excluding 6, were divided into two groups: Headache group complaints headache (113 patients: 23.4%) and remaining Headache-free group. Patients in younger (median age: 37 years) than (42 years), while...

10.3390/jcm12103533 article EN Journal of Clinical Medicine 2023-05-18

The objective of this study was to determine the clinical and endocrinological features sleep disturbance in patients with long COVID.This a single-center retrospective observational for who visited COVID-19 aftercare outpatient clinic (CAC) established Okayama University Hospital Japan during period from 15 February 2021 29 July 2022. COVID were divided into two groups based on presence or absence disturbance, laboratory characteristics analyzed.Out 363 COVID, after excluding 6 patients, 60...

10.3390/jcm11247332 article EN Journal of Clinical Medicine 2022-12-09

The most common symptom of post-acute coronavirus disease 2019 (COVID-19) is fatigue, and it potentially leads to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); however, a specific prognosticator lacking. We aimed elucidate the clinical characteristics patients who developed ME/CFS after COVID-19.In this retrospective observational study, visited Okayama University Hospital for long COVID between February 2021 March 2022 were investigated.Of 234 patients, 139 (59.4%) had...

10.3390/jcm12144737 article EN Journal of Clinical Medicine 2023-07-18

Evidence regarding treatment for the acute phase of COVID-19 has been accumulating, but specific long COVID/post-COVID-19 condition not yet established. Treatment with herbal medicine might be one option COVID, there little research on effectiveness COVID. The aim this study was to clarify prescription patterns Kampo medicines, which are medicines that originated in China and were developed Japan, general fatigue due A retrospective descriptive performed patients who visited a aftercare...

10.3390/medicina58060730 article EN cc-by Medicina 2022-05-28

After the acute phase of COVID-19, some patients have been reported to persistent symptoms including general fatigue. We established a COVID-19 aftercare clinic (CAC) provide care for an increasing number these patients. Here, we report case 36-year-old man who developed post-COVID fatigue after infection with SARS-CoV-2. In patient's fever resolved within four days; however, persisted three months, and he visited our CAC 99 days initial infection. Examination revealed high Aging Male's...

10.3390/medicina58040536 article EN cc-by Medicina 2022-04-13

Abstract Determination of long COVID requires ruling out alternative diagnoses, but there has been no report on the features diagnoses. This study was a single-center retrospective outpatients who visited our clinic between February 2021 and June 2023 that carried to determine characteristics diagnoses in patients with post-COVID-19 symptoms. In total 731 patients, 50 (6.8%) were newly diagnosed 52 diseases requiring medical intervention, 16 (32%) those (2.2% total) considered have priority...

10.1038/s41598-024-55526-3 article EN cc-by Scientific Reports 2024-03-05

Objectives: The aim of this study was to determine the characteristics hypozincemia in long COVID patients. Methods: This a single-center retrospective observational for outpatients who visited clinic established university hospital during period from 15 February 2021 28 2022. Characteristics patients with serum zinc concentration lower than 70 μg/dL (10.7 μmol/L) were compared normozincemia. Results: In total 194 after excluding 32 patients, detected 43 (22.2%) including 16 male (37.2%) and...

10.3390/jcm12052062 article EN Journal of Clinical Medicine 2023-03-06

Amid the Coronavirus Disease 2019 pandemic, we aimed to demonstrate accuracy of fingertip whole blood sampling test (FWT) in measuring antibody titer and uncovering its dynamics shortly after booster vaccination. Mokobio SARS-CoV-2 IgM & IgG Quantum Dot immunoassay (Mokobio Biotechnology R&D Center Inc., MD, USA) was used as a point-of-care FWT 226 health care workers (HCWs) who had received two doses BNT162b2 mRNA vaccine (Pfizer-BioNTech) at least 8 months prior. Each participant tested...

10.1038/s41598-022-24464-3 article EN cc-by Scientific Reports 2022-11-30

It is widely supposed that there no benefit, including extended survival and decreased rate of pneumonia, in patients with severe dementia receiving enteral tube feeding (TF). However, have been few studies comparing the frequency pneumonia before after TF dementia.Nine psychiatric hospitals Okayama Prefecture participated this retrospective survey. All inpatients fulfilling entry criteria were evaluated. subjects suffered from difficulty oral intake. Attending physicians thought could not...

10.1186/s12877-017-0662-6 article EN cc-by BMC Geriatrics 2017-11-20

Purpose: The present study aimed to clarify the effects of a hyperglycemic condition on clinical consequences long COVID. Methods: Among 643 patients who visited outpatient clinic our hospital from February 2021 September 2023, COVID were classified into (HG) group with casual blood glucose levels above 140 mg/dL and normoglycemic (NG) group. patients’ backgrounds, symptoms, health status including QOL evaluation scale (EQ-5D-5L), self-rating depression (SDS), F-scale questionnaire (FSSG),...

10.3390/jcm13144099 article EN Journal of Clinical Medicine 2024-07-13

Background The characteristics of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) related to COVID-19 have remained uncertain. To elucidate the clinical trend ME/CFS induced by long COVID, we examined data for patients who visited our outpatient clinic established in a university hospital during period from Feb 2021 July 2023. Methods Long COVID were classified into two groups, an group and non-ME/CFS group, based on three diagnostic criteria. Results prevalence was 8.4% (62 739...

10.1371/journal.pone.0315385 article EN cc-by PLoS ONE 2024-12-09

Background: Although many adverse reactions after SARS-CoV-2 vaccination have been reported, there few comprehensive studies on persistent symptoms vaccination. The aim of this study was to determine the clinical characteristics patients with various Methods: A retrospective descriptive performed for who visited a specialized clinic established at Okayama University Hospital evaluate events during period from April 2021 March 2023. Results: Descriptive analysis 121 127 period, and separate...

10.3390/vaccines11111661 article EN cc-by Vaccines 2023-10-30

Orthostatic intolerance (OI) is a key symptom of long COVID; however, the pathophysiology remains unknown. Among 688 COVID patients who visited our clinic during period from February 2021 to April 2023, 86 were suspected having OI and underwent an active standing test (ST) investigated elucidate clinical characteristics in with COVID. Of patients, 33 (38%) ST-positive. Nausea tachycardia daily life frequent complaints ST-positive group. The increase heart rate (HR) ST was significantly...

10.1038/s41598-024-67815-y article EN cc-by-nc-nd Scientific Reports 2024-07-24
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