A5020136536- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Echinoderm biology and ecology
- Aquaculture Nutrition and Growth
- Physiological and biochemical adaptations
- Marine Bivalve and Aquaculture Studies
- Fish Biology and Ecology Studies
- Genetic diversity and population structure
- Antimicrobial Peptides and Activities
- Cancer, Hypoxia, and Metabolism
- Reproductive biology and impacts on aquatic species
- Immune Response and Inflammation
- Forest, Soil, and Plant Ecology in China
- Gut microbiota and health
- S100 Proteins and Annexins
- Glycosylation and Glycoproteins Research
- Colorectal Cancer Surgical Treatments
- Neurobiology and Insect Physiology Research
- Reproductive tract infections research
- Advanced Glycation End Products research
- Marine and Coastal Ecosystems
- Advanced Control Systems Optimization
- High Altitude and Hypoxia
- Vascular Tumors and Angiosarcomas
- Ferroptosis and cancer prognosis
Shandong First Medical University
2022-2024
Dalian Ocean University
2015-2024
Dalian Minzu University
2024
Shandong Tumor Hospital
2022-2023
Academy of Medical Sciences
2023
Qingdao National Laboratory for Marine Science and Technology
2017-2021
Civil Aviation Flight University of China
2019
Liaoning Normal University
2010-2014
Chinese University of Hong Kong
2008
South China Agricultural University
2008
Similar to other industries, aquaculture constantly requires new techniques increase production yields. Modern technologies and different scientific fields, such as biotechnology microbiology, provide important tools that could lead a higher quality greater quantity of products. New feeding practices in farming typically play an role aquaculture, the addition various additives balanced feed formula achieve better growth is common practice many fish shrimp manufacturers farmers. As...
In fisheries, hypoxia stress is one of the most common environmental stresses that often lead to death large numbers fish and cause significant economic losses. The pituitary, an important endocrine gland, lies below hypothalamus region brain. It plays a crucial part in controlling vital physiological functions fish, such as growth, reproduction, responses stress. However, detailed mechanisms how affects these processes via pituitary remain largely unknown.
In fisheries, hypoxia stress is one of the most common environmental stresses that often cause significant harm and losses to aquaculture industry. The liver important metabolic organ body, which involved in energy metabolism, synthesizes various physiologically active substances, an target for fish. This study investigated how acute induces injury mortality Hexagrammos otakii. During treatment, reactive oxygen species (ROS), a intermediary made by mitochondrial respiratory chain, are highly...
Fat greenling (Hexagrammos otakii) is a kind of economic fish that widely consumed by human, and its intensive farming technology making important progress. However, high-density may cause the occurrence diseases in H. otakii. Cinnamaldehyde (CNE) new feed additive for aquatic animals has positive effect on disease resistance. In study, dietary CNE was evaluated growth performance, digestion, immune response, lipid metabolism juvenile otakii (6.21 ± 0.19 g). Six experimental diets were...
Introduction Artemisinin (ART) is very common as a diet additive due to its immunoregulatory activities. Nonetheless, the mechanism of ART in marine fish remains unknown. This study comprehensively examined effects and explored potential ameliorating intestinal immune disease (IID) fat greenlings (Hexagrammos otakii) . Methods results The targets were screened using Traditional Chinese Medicine Systems Pharmacology (TCMSP) database. Here, eight putative collected identified with Uniprot...
Cinnamaldehyde is an ideal feed additive with good immune enhancement and anti‐inflammatory regulation effects. However, the mechanism in fat greenling ( Hexagrammos otakii , H. ) remains unclear. The nine targets of cinnamaldehyde were gathered identified by Traditional Chinese Medicine Systems Pharmacology database Uniprot database, 1,320 intestinal inflammation disease (IIF)‐related proteins screened from DrugBank, Online Mendelian Inheritance Man (OMIM), Genecards, Pharmacogenetics...
Abstract To identify the functional gene fragment, a neutrophil inhibitory factor (NIF) like protein was found in buccal gland of Lampetra japonica , suggesting that this related lamprey represents novel class integrin receptor antagonists. The recombinant -NIF (rLj-NIF) identified by SDS-PAGE and purified using His·Bind affinity chromatography. Effect rLj-NIF on migration suggested can act as factor. Besides that, oxidative burst activity neutriphil tested flow cytometry dihydrorhodamine...
Apostichopus japonicus is a useful model for studying organ regeneration, and the gut microbiota important host regeneration. However, reconstruction process mechanisms of assembly during regeneration in sea cucumbers have not been well studied. In present study, was induced (via evisceration) A. japonicus, immune responses bacterial diversity were investigated to reveal its possible The results revealed that community involved two stages with distinct mechanisms, where reconstructed...
A hallmark of renal cell carcinoma (RCC) invasion is the degradation extracellular matrix (ECM) by local production gelatinase enzymes. Matrix metalloproteinase-9 (MMP-9)-induced cancer one pivotal steps in metastasis. It has been reported that tumor necrosis factor-α (TNF-α), a regulator MMP-9, can induce human cells. Previous work our laboratory shown rLj-RGD3, recombinant RGD (Arg-Gly-Asp)-toxin protein from buccal gland secretion Lampetra japonica, possesses anti-tumor activity. In this...
Abstract Lamprey is a representative of the agnathans, most ancient class vertebrates. Parasitic lampreys secrete anticoagulant from their buccal glands and prevent blood coagulation host fishes. We identified gland secretory protein-2 (BGSP-2) cDNA library Lampetra japonica. The full-length BGSP-2 gene was cloned recombinant protein generated. role on lymphocyte proliferation studied by examining its effects human T lymphocytes. found that lamprey able to effectively block cells in vitro...
Phoxinus lagowskii is a freshwater fish that widely distributed in China. In this study, comparative analysis of the mtDNA control region (D-loop) was performed to analyze natural population structure and genetic diversity 54 individuals from eleven locations (T1, T2, T3, T4, T5, T6, T7, T8, T9, T10 T11) which divided with reservoirs. The estimated haplotype nucleotide were 0.734 0.03514, respectively. An AMOVA indicated 79.78% total variation originated individual populations 20.22% came...