A5100368546- Fungal Biology and Applications
- Genomics and Phylogenetic Studies
- Nutritional Studies and Diet
- Berberine and alkaloids research
- Gut microbiota and health
- Microbial Natural Products and Biosynthesis
- Photosynthetic Processes and Mechanisms
- Plant Pathogens and Fungal Diseases
- Pharmacological Effects of Natural Compounds
- Plant Molecular Biology Research
- Natural product bioactivities and synthesis
- Nanocomposite Films for Food Packaging
- Diet and metabolism studies
- Flavonoids in Medical Research
- Plant nutrient uptake and metabolism
- Immunodeficiency and Autoimmune Disorders
- Plant Gene Expression Analysis
- Metabolomics and Mass Spectrometry Studies
- Plant-based Medicinal Research
- Plant Stress Responses and Tolerance
- Synthetic Organic Chemistry Methods
- Studies on Chitinases and Chitosanases
- Saffron Plant Research Studies
- Drug Transport and Resistance Mechanisms
- Dietary Effects on Health
Zhejiang University
2016-2025
Children's Hospital of Zhejiang University
2022-2025
Zhejiang Gongshang University
2022-2025
Anhui Academy of Agricultural Sciences
2022-2024
Tea Research Institute
2022-2024
Sichuan University
2015-2024
Anhui Agricultural University
2023-2024
Children's Hospital of Fudan University
2019-2024
Southern Medical University
2024
National Clinical Research
2024
Aspergillus flavus contamination in agriculture and food industries poses threats to human health, leading a requirement of safe effective method control fungal contamination. Chitosan-based nitrogen-containing derivatives have attracted much attention due their safety enhanced antimicrobial applications. Herein, new benzimidazole-grafted chitosan (BAC) was synthesized by linking the (CS) with simple benzimidazole compound, 2-benzimidazolepropionic acid (BA). The characterization BAC...
SUMMARY Camellia plants include more than 200 species of great diversity and immense economic, ornamental, cultural values. We sequenced the transcriptomes 116 from almost all sections genus . constructed a pan‐transcriptome with 89 394 gene families then resolved phylogeny based on 405 high‐quality low‐copy core genes. Most inferred relationships are well supported by multiple nuclear trees morphological traits. provide strong evidence that shared recent whole genome duplication event,...
Abstract Cervical cancer (CC) still remains a common and deadly malignancy among females in developing countries. More accurate reliable diagnostic methods/biomarkers should be discovered. In this study, we performed comprehensive analysis of metabolomics (285 samples) transcriptomics (52 on the potential implication metabolic characteristic description cervical cancer. Sixty-two metabolites were different between CC normal controls (NOR), which 5 (bilirubin, LysoPC(17:0), n-oleoyl...
The potential beneficial effect of individual antioxidants on mortality has been reported. However, the association overall intakes dietary with all-cause and cause-specific among adults diabetes remained unclear.A total 4,699 US were enrolled in 2003-2014 National Health Nutrition Examination Survey (NHANES) followed for until 31 December 2015. Dietary Antioxidant Quality Score (DAQS) Index (DAI), which indicate antioxidant properties, calculated based vitamins A, C, E, zinc, selenium,...
Pathogenic bacterial persisters are responsible for the recalcitrance of chronic and persistent infections to antimicrobial therapy. Although mechanisms persister formation survival have been widely studied in Escherichia coli, persistence Staphylococcus aureus remain largely unknown. Here, we screened a transposon mutant library clinical methicillin-resistant aureus(MRSA)strain, USA500 (ST8), under antibiotic pressure identified 13 genes whose insertion mutations resulted defect...
Eight new cembranoids, boscartins A–H (1, 2, and 4–9), the known incensole oxide were isolated from gum resin of Boswellia carterii. The absolute configurations 1, 4, unequivocally resolved using single-crystal X-ray diffraction analysis with Cu Kα radiation, configuration 5 was via electronic circular dichroism data. antiulcerative colitis activities compounds evaluated in an vitro x-box-binding protein 1 (XBP 1) transcriptional activity assay dual luciferase reporter detection. At 10 μM,...
Abstract Objective We aimed to investigate the relationships among nut consumption, gut microbiota, and body fat distribution. Methods studied 2255 Chinese adults in Lanxi Cohort living urban areas City, China. Fat distribution was assessed by dual‐energy x‐ray absorptiometry, consumption using food frequency questionnaires. 16S ribosomal RNA (rRNA) sequencing performed on stool samples from 1724 participants. Linear regression Spearman correlation were used all analyses. A validation study...
The massive accumulation of exudate containing high concentrations glucose causes wound infection and triggers the release inflammatory factors, which in turn delays closure diabetic wounds. In this study, a Janus membrane is constructed by combining oxidase (GOx) copper ions (Cu
is the major fungus that causes blue mold and produces patulin, threatening human health. Due to health environmental pollution concerns, chitosan (CS) has attracted more attention as a safer alternative synthetic fungicides for control of mold. In present study, four different benzimidazole groups were introduced onto CS by acylation reaction obtain benzimidazole-based derivatives (R1b-R4b). After being well-characterized with Fourier transform infrared spectroscopy (FTIR),...
Individuals who smoke tend to have a lower body mass index (BMI) but face an increased risk of obesity-related diseases. This study investigates this paradox from the perspective gut microbiota. We conducted microbiome analyses identify smoking-related microbial genera and created microbiota (SMI) using 16S rRNA sequencing data 4000 male participants in WELL-China cohort Lanxi cohort. employed logistic regression explore association between SMI obesity indices derived dual-energy X-ray...
Thirty quaternary coptisine derivatives from a synthesized library were found to activate the in vitro transcription of x-box-binding protein 1 (XBP1). Among these, dihydrocoptisines demonstrated by XBP1 transcriptional activity assays and animal experiments be much more active anti-ulcerative colitis (UC) agents than coptisines, tetrahydrocoptisines, positive control. Unsubstituted dihydrocoptisine exhibited significant anti-UC efficacy substituted at C-8 or C-13 position. The EC50 value...
Summary Resistance to inhibitors of cholinesterase 8 (Ric8) is a conserved guanine nucleotide exchange factor that involved in the regulation G‐protein signalling filamentous fungi. Here, we characterized an orthologous Ric8 (AoRic8) Arthrobotrys oligospora by multi‐omics analyses. The Aoric8 deletion (Δ ) mutants lost ability produce traps essential for nematode predation, accompanied marked reduction cAMP level. Yeast two‐hybrid assay revealed AoRic8 interacted with subunit Gα1. Moreover,...
Abstract Probiotics are defined as live microbial food elements that beneficial to human health. Lacticaseibacillus casei T1 was considered have potential a bioactive ingredient in functional foods, which isolated from kurut. Previous research by our group proved L. could prevent inflammatory responses caused Helicobacter pylori . This study aimed investigate whether treatment with resulted suppressive effect on H. -induced oxidative stress and responses. The results showed relieve...
Cysteine plays a pivotal role in the sulfur metabolism network of plants, intimately influencing conversion rate organic and plant’s capacity to withstand abiotic stresses. In tea serine acetyltransferase (SAT) genes emerge as crucial regulator cysteine metabolism, albeit with notable lack comprehensive research. Utilizing Hidden Markov Models, we identified seven CssSATs within plant genome. The results bioinformatics analysis indicate that these exhibit an average molecular weight 33.22 kD...
Abstract Seven in absentia (SINA) protein is one subgroup of ubiquitin ligases possessing an N‐terminal cysteine‐rich really interesting new gene (RING) domain, two zinc‐finger motifs, and a C‐terminal domain responsible for substrate‐binding dimerization. In tomato ( Solanum lycopersicum ), the SINA family has six members, we characterize this study all SlSINA ) genes products. Our results show that are differentially regulated leaf, bud, stem, flower, root. All proteins possess...