A5100766420- Nuclear Receptors and Signaling
- Parkinson's Disease Mechanisms and Treatments
- Intensive Care Unit Cognitive Disorders
- Tea Polyphenols and Effects
- Cardiac Ischemia and Reperfusion
- Gut microbiota and health
- Tryptophan and brain disorders
- Trauma Management and Diagnosis
- RNA regulation and disease
- Calpain Protease Function and Regulation
- MicroRNA in disease regulation
- Anesthesia and Neurotoxicity Research
- Cognitive Science and Education Research
- Cerebrovascular and genetic disorders
- Plant Gene Expression Analysis
- Plant Reproductive Biology
- Cerebrovascular and Carotid Artery Diseases
- Tracheal and airway disorders
- Plant biochemistry and biosynthesis
- Circular RNAs in diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Dysphagia Assessment and Management
Shanghai University of Traditional Chinese Medicine
2024
Ministry of Agriculture and Rural Affairs
2023
Jiangsu Academy of Agricultural Sciences
2023
Shanghai First People's Hospital
2019-2022
Sanda University
2019-2022
This study investigated the relationships between differentially co-expressed gene pairs or links (DCLs) and transcription factors (TFs) in regulatory network (GTRN) to clarify molecular mechanisms underlying pathogenesis of Parkinson's disease (PD).Microarray dataset GSE7621 from Gene Expression Omnibus (GEO) was used identify expressed genes (DEGs) perform Ontology (GO) enrichment analysis. Differentially (DCGs) DCLs were identified by DCGL package R soft-ware. that potentially related...
Ischemia/reperfusion (I/R) refers to situations where blood is perfused into ischemic or hypoxic tissues, potentially resulting in an inflammatory response and oxidative injury.This study was conducted explore the pathogenesis of I/R injury.GSE82146 extracted from Gene Expression Omnibus, consisting 15 complete global brain ischemia (CGBI) reperfusion hippocampus samples 12 non-ischemic control (NIC) samples. The differentially expressed genes (DEGs) between CGBI NIC were selected using...
This study was aimed to investigate the influence of miR-33-5p on M1/M2 polarization microglia and underlying mechanism. Transcriptome sequencing performed using from mimic control groups. In total, 507 differentially expressed genes, including 314 upregulated genes 193 downregulated were identified. The subnetwork module A, which extracted protein-protein interaction networks, mainly contained genes. Cdk1,Ccnb,and Cdc20, members module-A networks with highest degrees, possess potential...
Background: Investigate the correlation between low-density lipoprotein (LDL) cholesterol, homocysteine and cognitive function in patients with cerebral small vessel disease (CSVD). Methods: 240 CSVD confirmed by head MRI Department of Neurology from January 2020 to December 2023 were retrospectively included study. All had complete blood biochemical examination, their was evaluated Montreal Cognitive Assessment Scale (MoCA), after correcting for factor years education, divided into a group...
Objective To evaluate the swallowing function of patients with dysphagia after brainstem injury using manofluorography (MFG), analyzing abnormal biomechanical and kinematic parameters as well any correlation between changes in pharynx upper esophageal sphincter (UES) measured manometrically kinematics hyoid bone. Methods Thirteen (the patient group) 13 healthy participants control underwent manofluorography. Kinematics during were compared two groups correlations observations...