A5101438108- Cancer, Stress, Anesthesia, and Immune Response
- Neuropeptides and Animal Physiology
- Immune cells in cancer
- Lung Cancer Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Pain Management and Placebo Effect
- Neuroinflammation and Neurodegeneration Mechanisms
- Lipid metabolism and disorders
- Cardiovascular Disease and Adiposity
- Organ Transplantation Techniques and Outcomes
- Cancer, Hypoxia, and Metabolism
- Acupuncture Treatment Research Studies
- Cancer, Lipids, and Metabolism
- Anesthesia and Neurotoxicity Research
- Ultrasound in Clinical Applications
- Glioma Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Anomaly Detection Techniques and Applications
- Pharmacological Receptor Mechanisms and Effects
- Pulmonary Hypertension Research and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Ischemia and Reperfusion
- Medical Imaging and Pathology Studies
- Cancer Cells and Metastasis
- History of Medicine Studies
Zhejiang University
2025
Sichuan Cancer Hospital
2007-2024
University of Electronic Science and Technology of China
2017-2024
Reinforcement Learning from Human Feedback (RLHF) has emerged as a pivotal technique for large language model (LLM) alignment. This paper studies the setting of online RLHF and focus on improving sample efficiency. All existing algorithms in RLHF, whether doing passive exploration or active exploration, suffer complexity that scales exponentially with scale reward function. fundamental limitation hinders their effectiveness scenarios heavily skewed preferences, e.g. questions unique correct...
Currently, no reliable prognostic biomarkers have been identified for adult IDH wild-type (WT) diffuse low grade glioma (LGG). With data from The Cancer Genome Atlas (TCGA)-LGG, we examined the value of GABAA receptor subunits in WT LGG. Using 2016 WHO CNS tumor classification, re-classified TCGA-LGG and 95 patients. Among 16 subunit genes with RNA-seq data, eight showed significantly different expression LGG compared mutant (MT) cases. these genes, only GABRD was related to overall survival...
Objective To investigate the impact of electroacupuncture (EA) at bilateral acupuncture points ST36 and PC6 on level sedation in general anaesthesia. Methods 40 patients undergoing abdominal surgery were randomly divided into two groups: EA combined with anaesthesia (EA group, n=20) control group (n=20). The selected both groups. Target-controlled infusion (TCI) propofol was used for induction maintenance to reach an equilibrium state Narcotrend Index (NT index). In performed a Hans device....
Propofol‑based anesthesia has been reported to reduce the recurrence and metastasis of a number cancer types following surgical resection. However, effects propofol in bladder (BC) are yet be fully elucidated. The aim present study was investigate functions BC their underlying mechanisms. In study, expression microRNA (miR)‑145‑5p tissues cell lines evaluated using reverse transcription‑quantitative PCR, on cells were determined viability, wound healing Transwell invasion assays,...
It has been confirmed that morphine was detrimental to patients with cancers. Hence, we aimed reveal a certain mechanism of in cancer development.Microarray and GSEA analysis were utilized seek for differently expressed genes pathway.Bioinformatics identified downregulation MARCKS upregulation miR-543 samples treated morphine. FcγR-mediated phagocytosis pathway illustrated be upregulated the control. PANC-1 DU145 cell viability increased but apoptosis declined as concentration went up from...
Objective To evaluate the effect of sevoflurane preconditioning on expression heat shock protein 70(HSP70)during renal ischemia-reperfusion in rats. Methods Twenty-four pathogen-free healthy adult male Sprague-Dawley rats, weighing 250-300 g, aged 2-3 months, were divided into 3 groups(n=8 each)using a random number table: sham operation group(group S), I/R I/R)and SP). The animals anesthetized with 2% pentobarbital sodium 50 mg/kg.After right kidney was removed, left artery clamped...