A5012318480- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Genomics and Phylogenetic Studies
- Streptococcal Infections and Treatments
- Otolaryngology and Infectious Diseases
- Bacterial Infections and Vaccines
- Pneumocystis jirovecii pneumonia detection and treatment
- Antimicrobial Resistance in Staphylococcus
- Immunodeficiency and Autoimmune Disorders
- Bacterial biofilms and quorum sensing
- Ear Surgery and Otitis Media
- Mycobacterium research and diagnosis
Kempegowda Institute of Medical Sciences
2018-2024
Bangalore Medical College and Research Institute
2022
Abstract Background Klebsiella pneumoniae is a World Health Organization high-priority antibiotic-resistant pathogen. However, little known about lineages circulating in Nigeria. Methods We performed whole-genome sequencing (WGS) of 141 isolated between 2016 and 2018 from clinical specimens at 3 antimicrobial-resistance (AMR) sentinel surveillance tertiary hospitals southwestern conducted silico multilocus sequence typing; AMR gene, virulence plasmid, K O loci profiling; as well phylogenetic...
: Conventional microtiter plates lack the surface strength needed for effective binding of pneumococcal polysaccharide antigens. This study tackles limitation by altering polystyrene through carbodiimide activation under acidic pH conditions.
Background & objectives The Pneumococcal vaccines were introduced under the Universal Immunization Programme (UIP) in 2021 India. Drawing from collective experience of various nations, it is anticipated that there will be a substantial shift serotype patterns following introduction this vaccine. available data limited to years until 2018 when vaccine was only five States. present study carried out estimate changes serotypes and antimicrobial resistance pre- post-vaccine tertiary care...
Background Recurrent otitis media is one of the common infections childhood. The causative bacterial pathogen major risk factors recurrent infection. With limited availability Indian data, we performed this study to identify pathogens. Materials and Methods Otitis cases were diagnosed based on clinical criteria. Thirty-six middle ear fluid (MEF) samples collected by tympanocentesis cultured for Seventy-eight per cent had three previous episodes in past 6 months; remaining 22% four preceding...
Microbiology diagnostic laboratory plays a significant role in public health surveillance, outbreak investigation, infection prevention and control strategies. It is moving towards incorporating molecular biology techniques for the surveillance identification of pathogens causing infectious diseases. Next-generation sequencing (NGS) holds potential improving clinical microbiology. In addition to identifying more rapidly precisely than traditional methods, technologies can provide new...
Abstract Background S. aureus is a major pathogen in India, causing nosocomial infections, but little known about its molecular epidemiology and mechanisms of resistance hospital settings. Here, we use WGS to characterize 508 clinical isolates collected across India analyze them global context. Methods Whole-genome sequencing was performed on from 17 sentinel sites between 2014 2019 with the Illumina platform. AMR genotypes were predicted using Staphopia. Isolates carrying novel SCC mec...