BACKGROUND:Acupuncture, which has many good effects and few adverse effects, is widely recognized as an alternative therapy for depression in clinical practice. This study aimed to explore the mechanism of acupuncture antidepressant treatment. MATERIAL AND METHODS:In this experiment, Sprague-Dawley rats were randomly divided into 4 groups: control, chronic unpredictable mild stress (CUMS), acupuncture, fluoxetine groups. The CUMS, groups orphaned subjected 6 weeks, treated with their...

Acupuncture has shown the preventive effects on depression in rats with chronic unpredictable mild stress (CUMS). However, mechanisms of acupuncture for preventing still need to be explored. In study, was applied a rat model CUMS, high-mobility group box 1(HMGB1)/toll-like receptor 4 (TLR4) and brain-spleen axis were assessed.Male Sprague Dawley (SD) exposed CUMS two stressors per day 28 days. meantime, manual (at GV16 GV23 acupoints, once every other day) fluoxetine gavage (2.1 mg/kg, 0.21...

The treatment of depression with acupuncture has been documented. mechanism behind acupuncture's curative and preventative effects is still unknown. current study examined the on depression-like behaviors in a rat model chronic unpredictable mild stress (CUMS), while also exploring its potential mechanisms. A total six groups rats were randomly assigned: control, CUMS, acupuncture, fluoxetine, acupoint catgut embedding sham embedding. Fluoxetine (2.1 mg/kg) used for comparative research to...

Oxidative stress is closely related to the occurrence of depression. Acupuncture has been proved be an effective method for treating In order explore mechanism antidepressant effect acupuncture, this study performed acupuncture prevention on chronic unpredictable mild (CUMS) depression model rats, and observed hippocampal oxidative Nrf2 signaling pathway. Male SD rats were randomly divided into control group, CUMS fluoxetine group (n = 10/group). Fluoxetine, a common antidepressant, was used...

Purpose. To explore the therapeutic efficiency of acupuncture and related molecular mechanism neural plasticity in depression. Methods. Chronic unpredictable mild stress- (CUMS-) induced rats were established for depression animal model. There a total four rat groups, including control group, CUMS CUMS+acupuncture CUMS+fluoxetine group. The group fluoxetine given 3-week treatment after modeling intervention. researcher performed open-field, elevated plus maze, sucrose preference tests to...

Depression is associated with lowered mood, anxiety, anhedonia, cognitive impairments, and even suicidal tendencies in severe cases. Yet few studies have directed acupuncture's mechanism toward enhancing axonal repair correlated synaptic plasticity anti-inflammatory effects related to oxidative stress the hippocampus. Male Sprague-Dawley (SD) rats were randomly divided into control group (CON), chronic unpredictable mild (CUMS) group, CUMS + electroacupuncture (EA), fluoxetine (FLX) (n =...

Depression is a major mental disease worldwide, causing dysfunction of Lateral Habenular (LHb). As non-invasive alternative, acupuncture (AP) has been widely used to treat depression in clinic, yet few basic studies have focused on the effects and mechanism synaptic plasticity LHb. Therefore, this study aimed explore potential antidepressant effect acupuncture. Male Sprague-Dawley (SD) rats were randomly divided into control, chronic unpredictable mild stress (CUMS), AP, fluoxetine (FLX),...

The NLRP3-mediated pyroptosis, which could affect inflammation response, plays a key role in the development of depression. Acupuncture has been shown to be an effective treatment for In this study, we aimed determine whether acupuncture confer antidepressant activity via decreasing pyroptosis by reducing inflammation. Here, depression model rats was induced chronic unpredictable mild stress (CUMS) 4 weeks. group subjected at Shangxing (GV23) and Fengfu (GV16) acupoints 20 min every other...

Dimethyl sulfoxide (DMSO) has a variety of biological actions that suggest efficacy as neuroprotectant. We (1) tested the neuroprotective potential DMSO at different time windows on infarct size using 2,3,5-triphenyltetrazolium staining and (2) investigated effects ischemia evolution quantitative diffusion perfusion imaging in permanent middle cerebral artery occlusion (MCAO) model rats. In experiment 1, treatment (1.5 g/kg intravenously over 3 h) reduced volume 24 h after MCAO by 65% (...

BACKGROUND:Depression is a major mood disorder. Some patients have been reported to improve following acupuncture. This study aimed investigate the effects of acupuncture on behaviors associated with depression in chronic unpredictable mild stress (CUMS) rat model. The expression signaling pathway components nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) hippocampus plasma were also measured. MATERIAL AND METHODS:Male Sprague-Dawley rats (N=40) divided into control group (N=10),...

Acupuncture and moxibustion proved to be very effective in chronic atrophic gastritis (CAG). According the Chinese traditional medicine theory, diseases have an influence on function of liver kidney. However, there is little research demonstrate this theory. This study aimed at assessing 1H NMR-based metabolic profiling kidney CAG rats comparing difference between electroacupuncture treatment. Male SD were subjected modeling by intragastric administration mixture 2% sodium salicylate 30%...

Depression is a severe emotional condition that significantly affects the quality of life. Acupuncture exerts preventive effects on depression in rats with post-chronic unpredictable mild stress (CUMS). Methods The study involved chronic (CUMS) model mice to administer acupuncture as preventative measure investigate mechanism acupuncture's antidepressant and observe effect impact via Lateral Habenula (LHb) Gut-Liver-Brain Axis. researcher investigated molecules correlating nitric...

Depression is recognized globally as one of the most intractable diseases, and its complexity diversity make treatment extremely challenging. Acupuncture has demonstrated beneficial effects in various psychiatric disorders. However, underlying mechanisms acupuncture's antidepressant action, particularly depression, remain elusive. Therefore, this study aimed to investigate acupuncture on chronic unpredictability stress (CUMS)-induced depressive symptoms rats further elucidate molecular...

The paper presents the essential conditions for implementing fault tolerant control of switched reluctance motor drive system, such as structure motor, topology power converter, rotor position detector, current detector and strategies. experimental tested results developed prototype with are given.

With increasing utilization of gas turbine and power to technology, system natural can be tightly integrated into Integrated Electricity Gas Systems (IEGS). In this paper, static sensitivity analysis method based on unified flow model is used analyze the interaction mechanism between system. First, IEGS given. Based model, pressure-active injection matrix defined. Finally, combined with regional comprehensive energy index, impact nodal pressure analyzed, positioning weak parts IEGS. It...

To study the effect of acupuncture on rabbit bladder with urodynamic indexes. New Zealand male rabbits were divided into control group, model treatment group 1 treated by at Shenshu (BL 23) and 2 Zhongji (CV 3). The urine dynamic parameters through urethral catheter detected in each order: fluctuation pressure filling phase urinary flow rate urination phase, which used as quantification indexes function. abnormal was prepared administration cholinergic stimulant; Regulatory effects 3) state...

The paper presents a three-phase 12/8 structure switched reluctance motor (SRM) drive. construction of the stator and rotor in motor, position detector controller, are introduced. turn-off angle main switches power converter has been optimized by indexes high output power, efficiency, commutation abundance low relative braking torque at certain electric loads magnetic loads, while is supplied four circuits converter, respectively. developed prototype with PWM control tested experimentally...

Abstract With the increasing distribution network accidents caused by typhoon disasters, risk management in scenarios is necessary. A framework for power networks (PDNs) undergoing a disaster proposed. First, prediction model of PDN under conditions based on Batts developed to predict loss load ( LLR ) index and economic ELR before lands. Then, vulnerability overhead lines, considering failure frequency specific lines their importance, introduced use weak link identification identify links...

An optimal scheduling method for electrical-thermal integrated energy system considering heat storage characteristics of heating network is proposed in this paper. Firstly, a dynamic model transmission time delay proposed. The potential analyzed. Then, combined with the equipment model, an used as resource to participate system. Numerical studies demonstrate that and able reduce operational cost system, take advantage complementarity between electrical thermal power flow.

The paper presents the principles of two quadrants control, such as traction control and regenerative braking control. configuration switched reluctance motor drive for an electric bicycle, schematic diagram system, motor, rotor position detector, logic operation at scheme, are given. A comparison is given types three-phase motors, 12/8 6/8 structure same average electromagnetic torque in turn numbers per stator pole coil, resistance phased windings, basic output frequency power converter....