A5101993446- Obstructive Sleep Apnea Research
- Acupuncture Treatment Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cancer-related molecular mechanisms research
- Pregnancy and preeclampsia studies
- Genetic Associations and Epidemiology
- Asthma and respiratory diseases
- Dietary Effects on Health
- Immune Cell Function and Interaction
- Health and Wellbeing Research
- Obesity, Physical Activity, Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Antifungal resistance and susceptibility
- Circular RNAs in diseases
- Environmental Changes in China
- Microbial Metabolism and Applications
- NF-κB Signaling Pathways
- Phytoestrogen effects and research
- Flavonoids in Medical Research
- Lipid metabolism and disorders
- Traditional Chinese Medicine Studies
- Artificial Intelligence in Games
- Plant-based Medicinal Research
Kunming Municipal Hospital of Traditional Chinese Medicine
2019-2025
Guangzhou University of Chinese Medicine
2018-2024
Gansu Agricultural University
2024
Northeast Agricultural University
2022
Xiamen University
2010-2022
Guangdong Provincial Hospital of Traditional Chinese Medicine
2020-2021
Key Laboratory of Guangdong Province
2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
Third Affiliated Hospital of Guangzhou Medical University
2019
Guangzhou Medical University
2019
Diabetes and its related metabolic disorders have been reported as the leading comorbidities in patients with coronavirus disease 2019 (COVID-19). This clinical study aims to investigate features, radiographic laboratory tests, complications, treatments, outcomes COVID-19 or without diabetes. retrospective included 208 hospitalized (≥ 45 years old) laboratory-confirmed during period between 12 January 25 March 2020. Information from medical record, including outcomes, were extracted for...
Hypertension is one of the most common comorbidities in COVID-19 pneumonia. However, whether it an independent factor on severity and mortality has not been studied.In this study, 736 patients with a PCR-confirmed diagnosis were included from 12 January 2020 to 25 March 2020. All divided into two groups according or they hypertensive. After propensity score matching (PSM) remove interference mismatches baseline data, clinical characteristics outcomes angiotensin II receptor blocker (ARB)/ACE...
Oxidative stress is closely related to the occurrence of depression. Acupuncture has been proved be an effective method for treating In order explore mechanism antidepressant effect acupuncture, this study performed acupuncture prevention on chronic unpredictable mild (CUMS) depression model rats, and observed hippocampal oxidative Nrf2 signaling pathway. Male SD rats were randomly divided into control group, CUMS fluoxetine group (n = 10/group). Fluoxetine, a common antidepressant, was used...
Introduction: Obesity may lead to cognitive impairment and neuropsychiatric disorders, which are associated with changes in the brain cortical structure, particularly thickness. However, exact genetic association between obesity thickness remains inconclusive. We aimed identify relationship obesity-related traits [body mass index (BMI), waist-hip ratio (WHR), adjusted for BMI (WHRadjBMI)] Methods: Leveraging summary statistics of large-scale GWAS(s) conducted European-ancestry populations on...
Abstract Objective Traditional observational research has suggested a connection between socioeconomic position, mental health, and sleep apnea (SA), but the specifics of this are still unclear. Using Mendelian randomization approach, we intended to evaluate potential causal link status, SA. Methods Our employed summary statistics data from large-scale genome-wide association studies (GWAS) on In main study, SA was examined using inverse variance weighted approach. addition, as supplement,...
Abstract Background Chinese medicine Toujie Quwen granule (TJQW) has proven to be effective in the treatment of mild coronavirus disease 2019 (COVID-19) cases by relieving symptoms, slowing progression disease, and boosting recovery patients. But bioactive compounds potential mechanisms TJQW for COVID-19 prevention are unclear. This study aimed explore therapeutic mechanism based on an integrated network pharmacology approach. Methods TCMSP were used search screen active ingredients TJQW....
To investigate the prevalence and risk factors of COPD in Uyghur population Kashi region.From August 2018 to March 2019, we recruited participants ethnicity aged ≥40 years old from region using a combined cluster sampling random method. We collected potential questionnaire, conduced lung function portable pulmonary instrument.A total 2963 were included this analysis, whom 1268 males 1695 females. There 504 with COPD, generating 17.01%. With increase age, different genders increased...
Soybean is an important global crop for edible protein and oil, plant height a main breeding goal which closely related to its shape yield. In this research, high-density genetic linkage map was constructed by 1996 SNP-bin markers on the basis of recombinant inbred line population derived from Dongnong L13 × Henong 60. A total 33 QTL were identified, five repeatedly detected in multiple environments. addition, 455-germplasm with 63,306 SNP used multi-locus association analysis. 62 QTN...
Land use changes are the main cause for of carbon storage, which is great importance maintaining regional balance to make multi-scenario projections future land change and explore its impacts on storage. In recent years, under combination natural factors policies, with changing significantly, storage Weihe River Basin has also changed. Based PLUS-InVEST model, we assessed predicted spatial temporal variations ecosystem in explored land-use change. The results showed that distribution pattern...
Abstract We have previously shown that costimulation blockade using a combination of monoclonal antibodies (mAbs) – CTLA4Ig, to CD154, LFA-1, and OX40L can induce tolerance cardiac allografts in mice with adoptively transferred CD4+ memory T cells [1]. However, the effect costimulatory secondary allograft rejection has not been studied. B6 rejected BALB/c skin grafts for more than 4 weeks (defined as alloantigen-primed mice) were used recipients. The recipient treated mAbs OX40L, CD122 on...
Abstract Objective: The aim of this study was to evaluate the effect acupuncture injection therapy for patients with nonspecific chronic low back pain (CLBP) systematically. Methods: Four English online databases and 4 Chinese will be researched systematically from their inception December 31, 2018. Reference management software, Endnote X7, used manage screen records. After removing duplicate records, 2 independent reviewers select studies that meet inclusion criteria. “Risk table”...
Background Following COVID-19, reports suggest Long COVID and autoimmune diseases (AIDs) in infected individuals. However, bidirectional causal effects between AIDs, which may help to prevent diseases, have not been fully investigated. Methods Summary-level data from genome-wide association studies (GWAS) of (N = 52615) AIDs including inflammatory bowel disease (IBD) 377277), Crohn’s (CD) 361508), ulcerative colitis (UC) 376564), etc. were employed. Bidirectional gauged by exploiting...
To observe the effects of electroacupuncture (EA) on type 2 innate lymphoid cell (ILC2) function in white adipose tissue (WAT) high-fat diet (HFD)-induced obese rats to reveal mechanism underlying weight loss. Male Winstar (n=15) were randomly divided into control, HFD, and HFD+EA groups, with five each group. An obesity model was established by feeding a HFD. EA (2 Hz, 1 mA) applied "Zhongwan (CV12)" bilateral "Tianshu (ST25)" "Zusanli (ST36)" "Sanyinjiao (SP6)" for 15 min, 7 days week,...
PRKCI is abnormally expressed in various cancers, but its role osteosarcoma unknown. This study aimed to explore the biological function of and potential molecular mechanism. expression was evaluated cell lines using Western blot analysis reverse transcription PCR. The CCK-8 assay, colony formation flow cytometry, Transwell wound-healing assay were used detect proliferation, colony-forming capacity, cycle, migration, invasion cells when overexpressed or knocked down. interaction between...
Although the infectious diseases tuberculosis (TB) and cryptococcosis both cause formation of single or multiple nodules in immunodeficient hosts, cases co-infection these are rarely seen. We report a patient who was co-infected with TB cryptococcosis. A male no clinical evidence immunodeficiency presented 3-week history abdominal distension accompanied by oedema recurring lower extremities. The diagnosed tuberculous peritonitis pleurisy an puncture biopsy. Several months after being treated...
Objective: To explore the cognitive functions of elderly aged 60 years and above in Xiamen, whether TV watching time would affect those functions. Methods: We conducted a cross-sectional study on 3 230 registered individuals Xiamen from July to October 2016 with multi-stage random sampling method. Montreal Cognitive Assessment (MoCA) was used measure ordinal logistic regression quantify their associations time. Results: A total 2 944 respondents were included this study. The overall age them...
Abstract Objective Traditional observational research has suggested a connection between socioeconomic position, mental health, and sleep apnea (SA), but the specifics of this are still unclear. Using Mendelian randomization approach, we intended to evaluate potential causal link status, SA. Methods Our employed summary statistics data from large-scale genome-wide association studies (GWAS) on In main study, SA was examined using inverse variance weighted approach. addition, as supplement,...