A5100361372- Traditional Chinese Medicine Studies
- Medical Research and Treatments
- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Analysis
- Healthcare and Venom Research
- Phytochemistry and Biological Activities
- Pharmacological Effects of Natural Compounds
- Essential Oils and Antimicrobial Activity
- Phytochemical and Pharmacological Studies
- Lipid metabolism and disorders
- Ginseng Biological Effects and Applications
- Natural product bioactivities and synthesis
- Neurological Disease Mechanisms and Treatments
- Cardiovascular and exercise physiology
- Phytochemical Studies and Bioactivities
- Cancer-related molecular mechanisms research
- Phytochemicals and Antioxidant Activities
- Herbal Medicine Research Studies
- Drug-Induced Hepatotoxicity and Protection
- Metabolomics and Mass Spectrometry Studies
- Phytochemistry and Bioactive Compounds
- Flavonoids in Medical Research
- Medicinal Plant Pharmacodynamics Research
- Head and Neck Cancer Studies
- Pineapple and bromelain studies
Tonghua Normal University
2009-2024
Third People's Hospital of Yunnan Province
2023
Yunnan University
2023
Beijing Friendship Hospital
2023
Capital Medical University
2023
Baotou Medical College
2023
Yanbian University
2023
Beijing University of Chinese Medicine
2022
Changchun University of Chinese Medicine
2020-2021
Guangzhou University of Chinese Medicine
2020
The conventional use of Heracleum moellendorffii Hance is for wind dispelling and toxin removal. This research aims to enhance the understanding flowering aerial parts this plant by analyzing its volatile oil. Hydrodistillation was employed extract essential oil, which subsequently analyzed using gas chromatography coupled with mass spectrometry. analysis revealed presence 50 compounds, accounted 92.67% oil's composition. major constituents include germacrene D (21.78%), n-octyl acetate...
DanHong injection is a Danshen (<i>Salvia miltiorrhiza</i> roots)-based injectable solution for treatment of coronary artery disease and ischemic stroke. catechols are believed to be responsible the injection's therapeutic effects. This study aimed characterize systemic exposure elimination in human subjects, rats, dogs receiving intravenous injection. A total 28 were detected, with content levels 0.002–7.066 mM injection, major compounds included tanshinol, protocatechuic aldehyde,...
Tanshinol has desirable antianginal and pharmacokinetic properties is a key compound of <i>Salvia miltiorrhiza</i> roots (Danshen). It extensively cleared by renal excretion. This study was designed to elucidate the mechanism underlying tubular secretion tanshinol compare different ways manipulate systemic exposure compound. Cellular uptake mediated human organic anion transporter 1 (OAT1) (<i>K</i><sub>m</sub>, 121 <i>μ</i>M), OAT2 (859 OAT3 (1888 OAT4 (1880 <i>μ</i>M) rat Oat1 (117...
Aberrant activation of platelets has a critical role in thrombotic vascular events, including atherosclerosis, arterial thrombosis and myocardial infarction. The process platelet is associated with multiple intracellular signaling pathways, the phosphoinositide 3‑kinase/AKT serine/threonine kinase (Akt) pathway. well‑known medicinal herb Rhizoma Ligusticum Wallichii (RLW) long been used China to clinically treat various cardiovascular disorders. As most pharmacologically active component...
Euphorbia fischeriana has a long-standing history of use in traditional medicine for the treatment tuberculosis diseases. However, plant’s therapeutic potential extends beyond this specific ailment. The present study aimed to investigate antioxidant properties and lay groundwork further research on its applications. Phytochemical tests were performed plant, 11 types phytochemicals identified. Ultraviolet–visible spectrophotometry was used evaluate active components eight different solvent...
In traditional medicine, Plagiorhegma dubia Maxim (PD) is used to treat diabetes, irritability, insomnia, high fever, and coma. this study, identify the components in PD, we first performed three preliminary phytochemical tests, which were all positive for presence of alkaloids. Next, evaluated total alkaloid content 13 different vitro antioxidant experiments solvent extracts PD. According results, methanol extract was selected further research. Ultra-performance liquid chromatography with...
Laportea bulbifera (Sieb. et Zucc.) Wedd., a plant with long history of medicinal use, possesses uncertainly defined medicament portions while its antioxidant capacity remains largely unexplored. To gain better understanding value, this study focused on investigating the aboveground part (LBAP) and root (LBR). Through an assessment bioactive compound content, significant finding emerged: LBR exhibited notably higher levels these phytochemicals compared to LBAP. This observation was further...
This study was to observe the changes of neuronal and inducible nitric oxide synthase (nNOS & iNOS) as well their mRNAs in rostral ventrolateral medulla (RVLM) stress-induced hypertensive rats before after acupuncture, thereby infer curative mechanism acupuncture on hypertension. The result indicated that systolic blood pressure (SBP) stress group increased significantly (P < 0.01), it accompanied expression nNOS RVLM, including immunoreactive neuron number 0.05), optical density (OD) mRNA...
Abstract In this study, we investigated the effect of Hippophae rhamnoides L. (HRP) on activity CYP2D6 via CAMP/PKA/NF-κB pathway in rats with Bacille Calmette–Guerin (BCG)-induced immunological liver injury. BCG (125 mg/kg) was injected to establish rat model HRP administered intragastrically for one week as intervention drug. Proteomics techniques were used analyze protein expression levels, obtaining a comprehensive understanding injury process. ELISA or western blotting detect specific...
Acupuncture is a widely practiced, convenient, and safe treatment modality within complementary integrative medicine. Increasing studies have revealed the efficacy of acupuncture for osteoporosis in both human non-human subjects. The aim present study was to assess improvement after overall adjustment (OA) as well its endocrine-modulating effect an ovariectomized rat model.In total, 32 female Sprague-Dawley (SD) rats were randomly divided into sham, model, ovariectomy+estrogen (OVX+E),...
To assess the preventive effects of acupuncture at back-shu and front-mu acupoints on rats with restraint water-immersion stress (RWIS)-induced gastric ulcer.Thirty-six were randomly divided into four groups for 10 days treatment as follows: normal group received no treatment; model RWIS-induced ulcer; omeprazole was administered orally every 2 days; electroacupuncture RN12 BL21 days. After treatment, except group, all induced ulcer by RWIS 3 h. The index (UI), inhibition rate,...
OBJECTIVE To observe the effect of electroacupuncture preconditioning at Zusanli(ST36，Lower Confluent point) and Zhongwan(CV12，Front-Mu combination on oxidative stress inflammation-related indicators, Toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88) inhibitor-α nuclear transcription κB (IκB-α) in serum gastric tissue rats with ulcer(SGU)，so as to explore its mechanisms underlying prevention SGU. METHODS A total 36 Wistar were randomly divided into blank control, model,...
Acupoint catgut embedding (ACE) has been proven to be effective and safe in the treatment of obesity, but few studies have conducted involving its central mechanisms. Our previous study demonstrated effectiveness Shu-Mu ACE abdominal obesity (AO). However, neurological mechanism for weight loss not yet elucidated. The combination Shu Mu acupoints may related integrative effects brain. This paper aims explore potential neural mechanisms female patients with AO.A total 100 eligible AO 20...
This study reported the isolation and identification of bioactive compounds from Dioscorea nipponica Makino, a plant used in traditional medicine for various ailments. Nine were isolated, including new compound named as diosniposide E, which was elucidated by analyzing its 1H-NMR, 13C-NMR, DEPT, COSY, HMBC MS data comparing them with available literature. The other eight identified known compounds. Theoretical calculations energy generation molecular electrostatic potential surface map...