A5044704415- Acupuncture Treatment Research Studies
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Gastrointestinal motility and disorders
- Medical Research and Treatments
- Complementary and Alternative Medicine Studies
- Myofascial pain diagnosis and treatment
- Sleep and related disorders
- Infant Health and Development
- Sleep and Wakefulness Research
- Menstrual Health and Disorders
- Stress Responses and Cortisol
- Pain Management and Placebo Effect
- Endometriosis Research and Treatment
- Genomics, phytochemicals, and oxidative stress
- Psychosomatic Disorders and Their Treatments
- Reproductive System and Pregnancy
- Gut microbiota and health
- Pain Mechanisms and Treatments
- Sexual function and dysfunction studies
- Ophthalmology and Visual Impairment Studies
- Pelvic floor disorders treatments
- Nerve injury and regeneration
- Biological Activity of Diterpenoids and Biflavonoids
- Polysaccharides and Plant Cell Walls
Changchun University of Chinese Medicine
2016-2025
Xian Yang Central Hospital
2025
Anhui University of Technology
2024
Jilin Academy of Traditional Chinese Medicine
2023
Changchun University
2007-2023
National Natural Science Foundation of China
2021
Creative Commons
2021
Weatherford College
2020-2021
International Platform of Registered Systematic Review and Meta-analysis Protocols
2021
National Taiwan Normal University
1998
Oxidative stress contributes to the pathogenesis of diabetic nephropathy (DN). Nuclear factor erythroid 2-related 2 (NRF2) plays a key role in cellular defense against oxidative stress. NRF2 activators have shown promising preventive effects on DN. Sodium butyrate (NaB) is known activator NRF2. However, it unknown whether required for NaB protection Therefore, streptozotocin-induced C57BL/6 Nrf2 knockout and their wild-type mice were treated presence or absence 20 weeks. Diabetic mice, but...
Diarrhea-predominant irritable bowel syndrome (IBS-D) and functional diarrhea (FD) are highly prevalent, the effectiveness of acupuncture for managing IBS-D FD is still unknown. The aim this study was to compare electroacupuncture with loperamide. It a prospective, randomized, parallel group controlled trial. A total 448 participants were randomly assigned He (n = 113), Shu-Mu 111), He-Shu-Mu 112), or loperamide 112). Participants in 3 groups received 16 sessions during 4-week treatment...
Background: Electroacupuncture (EA) is a promising treatment for gastrointestinal disorders, yet the efficacy of different acupoint combinations remains mechanistically undefined. We evaluated therapeutic effects on mucosal inflammatory injury induced in rat model gastric ulcer (GU) and dissected its molecular mechanisms through transcriptomic profiling. Methods: A GU was established using hypothermic restrained water immersion stress. EA therapy administered to He-Mu (ST36-CV12), Shu-Mu...
Cancer is a complex systemic disease. As key component of traditional Chinese medicine, acupuncture clinically proven medical treatment for many diseases, and it also has preventative effects as balances the body, allowing to self-regulate. For cancer patients, widely used complementary therapy boost immune system reduce side radiotherapy chemotherapy. However, few studies have determined how against cancer, especially in regulating intestinal flora tumor-burdened mice.
Abstract Background Primary insomnia (PI) is characterized by difficulties in initiating sleep or maintaining sleep, which lead to many serious diseases. Acupuncture for PI has drawn attention with its effectiveness and safety. However, the operation of choosing acupoints lacks scientific suggestion. Our trial aims provide reference basis selection explore possible mechanism. Methods A patient-assessor-blinded, randomized sham controlled was designed compare efficacy 5-weeks acupuncture at a...
Activation of nuclear factor erythroid 2‐related 2 (NRF2) has been found to ameliorate diabetic testicular damage (DTD) in rodents. However, it was unclear whether NRF2 is required for these approaches DTD. Epigallocatechin gallate (EGCG) a potent activator and shown beneficial effects on multiple complications. the effect EGCG not studied The present study aims explore role both self protection against Therefore, streptozotocin‐induced C57BL/6 wild type (WT) Nrf2 knockout (KO) mice were...
Accumulating evidence suggests that sleep deprivation (S‐Dep) is a critical risk factor for depression. Electroacupuncture (EA) treatment has been reported to ameliorate posttraumatic stress disorder‐ (PSTD‐) like behavior and enhance hippocampal neurogenesis. However, whether EA any beneficial effect on S‐Dep‐induced depression‐like still unknown. In the present study, we focused at Baihui (GV20) can deterioration of S‐Dep in mice. Mice were randomly divided into normal, S‐Dep, + EA, sham...
Primary dysmenorrhea is a common gynecological disease with typical clinical symptoms and diverse treatment methods. Acupoint patch therapy one of the traditional external treatments Chinese medicine, long history, has been widely used in many diseases China. Graphene nuangong acupoint plaster (GNGAP) developed based on acupoints new materials have primary dysmenorrhea, satisfactory therapeutic effects achieved. However, underlying mechanisms GNGAP still need further investigation. In this...
To investigate the effects of graphene-based warm uterus acupoint paste on uterine Toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88)/nuclear transcription factor-kappa B p65 (NF-κB p65) signaling pathway and Th1/Th2 immune balance in primary dysmenorrhea ( PD ) model rats, so as to reveal its immunological mechanisms relieving dysmenorrhea.
The purpose of this study is to investigate the specific innervations on “Weizhong” (BL40) and “Huantiao” (GB30) by using a dual neural tracing technique. After Alexa Fluor 488 594 conjugates cholera toxin subunit B (AF488/594-CTB) were, respectively, injected into BL40 GB30 in same rat, labeled sensory motor neurons were examined rat’s dorsal root ganglia (DRGs) spinal cord at thoracic (T) lumbar (L) segments with laser scanning confocal microscope. In cases injection, AF488-CTB located L...
The most effective among the acupoints remains to be determined for treating diabetic gastroparesis (DGP). This study aimed compare single and combination their effectiveness in DGP.
Endometriosis, identified by the abnormal growth of endometrial cells beyond inner lining uterus, often manifests through symptoms like painful menstruation and challenges in conceiving. Observational studies suggest that endometriosis is comorbid with mental disorders, including anxiety depression. The nature these connections, whether they are causal, still debated calls for further empirical evidence. We utilized a bidirectional 2-sample Mendelian randomization (MR) approach, harnessing...
To validate and explore the application of a rat model chronic constriction injury to partial sciatic nerve in investigation acupuncture analgesia.Chronic (CCI) (CCIp) models were generated by ligating either trunk or its branches rats. Both evaluated via paw mechanical withdrawal latency (PMWL), threshold (PMWT), nociceptive reflex-induced electromyogram (C-fiber reflex EMG), dorsal root ganglion immunohistochemistry. Electroacupuncture (EA) was performed at GB30 study analgesic effects on...
One of the most important aspects clinical acupuncture practice, like diabetic gastroparesis, is selection suitable acupoints. Furthermore, it critical to examine therapeutic impact differences between distal and local acupoints, as well prescription their combination. In this study, gastroparesis rats were treated by needling Zhongwan (CV12) Zusanli (ST36), then used Single Photon Emission Computed Tomography-CT (SPECT-CT) technology assess effects promoting gastric motility. addition,...
Objectives This study was performed to investigate the innervations related acupuncture point PC8 in rats using a neural tracing technique. Methods After 6 μL of 1% cholera toxin subunit B (CTB) injected into site between second and third metacarpal bone rats, corresponding human body, CTB labelling examined with immunofluorescence immunohistochemistry dorsal root ganglia (DRG), spinal cord brainstem. Results All appeared on ipsilateral side injection. The labelled sensory neurons...
The conception and the history of ashi point, tender point myofascial trigger are described in paper. All three kinds reaction musculoskeletal pain visceral diseases. Theoretically, originates from theory muscle region meridian, soft tissue muscles muscular fasciae. Anatomically, is localized on boundary between muscles, attachment to skeleton (the starting ending points) motor neuromuscles. Pathologically, reflects disorders internal organ, few organ. To identify relationship among them...
In planning for a large‐scale multicenter trial to evaluate the effect of acupuncture treatment lateral elbow pain, pilot study was conducted. This prospective, investigator‐ and patient‐blinded, nonrandomized, placebo controlled trial. Subjects were evaluated at baseline, before fourth, seventh, ninth treatment, two‐week posttreatment follow‐up. The group received unilateral LI 10 11 affected side with manual needle manipulation; control sham‐laser same acupoints. Measures included (i)...
Motion acupuncture (MA) refers to a special technique where patient carries out body motions under supervision of doctors with needles inserted and retained in the points. The include active movement, allocinesis load exercise. MA involves three major procedures,namely target examination (finding target), techniques (motion allowed after acupuncture) motion methods (needle-retaining motion), which are described detail this article. can be found by examining along meridians, sinews, muscles...