A5101425955- Advanced Radiotherapy Techniques
- Pneumonia and Respiratory Infections
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Bacterial Infections and Vaccines
- Plant Molecular Biology Research
- Traditional Chinese Medicine Studies
- Radiation Therapy and Dosimetry
- Cancer Immunotherapy and Biomarkers
- Plant Gene Expression Analysis
- Respiratory viral infections research
- Microbial infections and disease research
- Breast Cancer Treatment Studies
- Cancer Research and Treatments
- Head and Neck Cancer Studies
- Metabolomics and Mass Spectrometry Studies
- Menstrual Health and Disorders
- Urinary Bladder and Prostate Research
- Colorectal and Anal Carcinomas
- Cerebrovascular and Carotid Artery Diseases
- Proteoglycans and glycosaminoglycans research
- Digital Radiography and Breast Imaging
- Tuberculosis Research and Epidemiology
- Acupuncture Treatment Research Studies
Union Hospital
2024-2025
Huazhong University of Science and Technology
2024-2025
Tianjin University of Traditional Chinese Medicine
2020-2025
Shandong First Medical University
2025
Tianjin University
2024
Tianjin Hospital
2024
Tianjin Fourth Hospital
2024
Southwest University
2024
Guangzhou Medical University
2015-2023
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2021-2022
Abstract The aim of this study was to estimate the radiation-related secondary cancer risks in organs during treatment breast with different radiotherapy techniques, such as three-dimensional conformal (3D-CRT), intensity modulated (IMRT), and volumetric arc therapy (VMAT). plans for 26 patients who received whole-breast irradiation at a dose 50 Gy included tangential field 3D-CRT hard-wedges (W-TF), IMRT (2F-IMRT), multiple (6F-IMRT), double partial arcs Patients were divided into three...
The efficacy of current therapies for ovarian cancer is limited due to the multilevel and complex tumor microenvironment (TME), which induces drug resistance progression in a single treatment regimen. Additionally, poor targeting insufficient tissue penetration are important constraints treatment. We constructed PH20-overexpressing cancer-associated fibroblast (CAF)-cancer hybrid-cell membrane vesicles (PH20/CCM) dual-targeted delivery carboplatin (CBP) siRNA p65 (sip65) loaded on poly...
Traditional Chinese medicine (TCM) has been utilized for the treatment of colon cancer. Qizhen decoction (QZD), a potential compound prescription TCM, possesses multiple biological activities. It proven clinically effective in However, molecular mechanism anticolon cancer activity is still not clear. This study aimed to identify chemical composition QZD. Furthermore, collaborative analysis strategy network pharmacology and cell biology was used further explore critical signaling pathway QZD...
Summary In plant species, anthocyanin accumulation is specifically regulated by light signaling. Although the CONSTITUTIVELY PHOTOMORPHOGENIC1/SUPPRESSOR OF PHYA‐105 (COP1/SPA) complex known to control biosynthesis in response light, precise mechanism underlying this process remains largely unknown. Here, we report that Increase BONSAI Methylation 1 (IBM1), a JmjC domain‐containing histone demethylase, participates regulation of light‐induced Arabidopsis . The expression IBM1 was induced...
Gestational diabetes mellitus (GDM) is the most common pregnancy complication, significantly affecting maternal and neonatal health. Polycystic ovary syndrome (PCOS) a endocrine disorder characterized by metabolic abnormalities, which notably elevates risk of developing GDM during pregnancy. In this study, we utilized ultra-high-performance liquid chromatography for untargeted metabolomics analysis serum samples from 137 pregnant women in early-to-mid-pregnancy. The cohort consisted...
Endometrial cancer poses a significant threat to women's health. Doxorubicin is commonly used in chemotherapy for advanced and recurrent cases; however, low sensitivity frequently limits its effectiveness. In this study, we verified that SRC modulates the of endometrial doxorubicin developed targeted silencing drug delivery platform employs rolling circle amplification dual-multivalent aptamers precisely deliver therapeutics directly tumor cells. This enhanced cell by modulating...
As hybrid radiotherapy technique can effectively balance dose distribution between targets and organs, it is necessary to evaluate the late effects related radiotherapy. The aim of study was calculate provide individual estimates risks for techniques in breast cancer patients.Whole-breast irradiation performed 43 patients by using 3D conformal, intensity-modulated techniques. excess absolute risk (EAR), lifetime attributable (LAR) normal tissue complication probability (NTCP) were calculated...
This study conducted a meta-analysis to compare the effectiveness and safety of negative pressure wound therapy (NPWT) with moist care (MWC) in treatment diabetic foot ulcers (DFUs).The PubMed, EMBASE, CENTRAL were searched by 2 authors, identify randomized controlled trials comparing clinical outcomes patients treated NPWT versus MWC for DFUs. Meta-analyses performed several outcomes, including healing results, amputation or resection incidence, risk adverse events, utilizing "meta" package...
Abstract: The mutL homolog-1 ( MLH1 ) is a DNA mismatch repair gene and has been reported to be frequently methylated in numerous cancers. However, the association between methylation esophageal cancer (EC), as well its clinical significance, remains unclear. Hence, we conducted systematic meta-analysis based on 19 articles (including 1384 ECs, 345 premalignant lesions, 1244 healthy controls). Our analysis revealed that frequency of was significantly elevated during EC carcinogenesis. In...