A5087642110- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive Health and Technologies
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Hormonal and reproductive studies
- Advanced Neuroimaging Techniques and Applications
- Selenium in Biological Systems
- Assisted Reproductive Technology and Twin Pregnancy
- Birth, Development, and Health
- Reproductive biology and impacts on aquatic species
- Natural Antidiabetic Agents Studies
- Diet and metabolism studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Bee Products Chemical Analysis
- Stress Responses and Cortisol
- Urologic and reproductive health conditions
- COVID-19 Impact on Reproduction
- Genomics and Rare Diseases
- Prenatal Substance Exposure Effects
- Neonatal and fetal brain pathology
- Cannabis and Cannabinoid Research
- Phytoestrogen effects and research
- Spaceflight effects on biology
Mohammed Bin Rashid University of Medicine and Health Sciences
2019-2025
Stellenbosch University
2016-2025
South African Medical Research Council
2020-2025
King Chulalongkorn Memorial Hospital
2024
University of Okara
2024
Lions Gate Hospital
2024
Singapore General Hospital
2024
Chulalongkorn University
2024
University of the Free State
2024
University of Cape Town
2003-2022
A common limitation of neuroimaging studies is their small sample sizes. To overcome this hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium combines data from many institutions worldwide. However, introduces heterogeneity due to different scanning devices and sequences. ENIGMA projects commonly address with random-effects meta-analysis or mixed-effects mega-analysis. Here we tested whether batch adjustment method, ComBat, can further reduce site-related...
Left–right asymmetry is an important organizing feature of the healthy brain that may be altered in schizophrenia, but most studies have used relatively small samples and heterogeneous approaches, resulting equivocal findings. We carried out largest case–control study structural asymmetries with MRI data from 5,080 affected individuals 6,015 controls across 46 datasets, using a single image analysis protocol. Asymmetry indexes were calculated for global regional cortical thickness, surface...
Various systems of antioxidants exist endogenously in the body to help protect it against free radical damage by scavenging excessive ROS and RNS. Melatonin, a hormone secreted pineal gland, responsible for controlling circadian rhythm, is one such endogenous antioxidant. Melatonin has been reported be present human seminal fluid, but its antioxidant activities semen are rather contradictory. This study aimed at establishing effects melatonin treatment on spermatozoa. Spermatozoa were...
Assessment of sperm morphology (including morphometry) is extensively used to determine one the qualities a semen sample and depends on differential staining spermatozoa. A technique should cause as little change dimensions form possible in order reliably evaluate morphometric features sperm. Various techniques have been employed, but only few recommended by World Health Organization are amenable automated morphometry analysis. Our study was aimed at comparing effect three [Papanicolaou...
Abstract Background Oxidative stress plays a key role in the etiology of male infertility. Significant alterations sperm proteome are associated with poor semen quality. The aim present study was to examine if elevated levels reactive oxygen species cause an alteration proteomic profile spermatozoa. Methods This prospective consisted 52 subjects: 32 infertile men and 20 normal donors. Seminal ejaculates were classified as ROS+ or ROS- evaluated for their profile. Samples pooled subjected...
Several factors have been shown to influence semen parameters, one of which is sexual abstinence; a clinical criteria included in the evaluation provide maximum sperm quality. The aim present study was assess effect daily ejaculation frequency on conventional and functional parameters. Semen samples were collected over period two weeks every second sample per person processed analyzed according World Health Organization guidelines. Furthermore, mitochondrial function, intracellular reactive...
Abstract Schizophrenia is frequently associated with obesity, which linked neurostructural alterations. Yet, we do not understand how the brain correlates of obesity map onto changes in schizophrenia. We obtained MRI-derived cortical and subcortical measures body mass index (BMI) from 1260 individuals schizophrenia 1761 controls 12 independent research sites within ENIGMA-Schizophrenia Working Group. jointly modeled statistical effects BMI using mixed effects. was additively structure many...