A5009357260- Dialysis and Renal Disease Management
- Pharmacological Effects and Toxicity Studies
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Neurological and metabolic disorders
- Heavy Metal Exposure and Toxicity
- Renal and Vascular Pathologies
- Pharmaceutical Practices and Patient Outcomes
- Central Venous Catheters and Hemodialysis
- Atrial Fibrillation Management and Outcomes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Acute Kidney Injury Research
- Renal Diseases and Glomerulopathies
- Bipolar Disorder and Treatment
- COVID-19 and healthcare impacts
- Muscle and Compartmental Disorders
- Poisoning and overdose treatments
- Drug-Induced Hepatotoxicity and Protection
- Pharmaceutical and Antibiotic Environmental Impacts
- Nonmelanoma Skin Cancer Studies
- Cerebrospinal fluid and hydrocephalus
- Potassium and Related Disorders
- Therapeutic Uses of Natural Elements
- Membrane Separation Technologies
- Microplastics and Plastic Pollution
Centre Hospitalier Universitaire de Poitiers
2005-2023
Université de Poitiers
2019-2023
Génétique, Génomique Fonctionnelle et Biotechnologies
2022
Centre Hospitalier Régional Universitaire de Brest
2022
Inserm
2021
Landscape Research Group
2021
RELX Group (Netherlands)
2021
RELX Group (United States)
2021
Agence de la Biomédecine
2020
Centre de Référence des Maladies Autoinflammatoires et des Amyloses
2018
Accumulation of middle-weight uraemic toxins in haemodialysis (HD) patients results increased morbidity and mortality. Whether medium cut-off HD (MCO-HD) improves removal remains to be demonstrated.This cross-over prospective study included 40 randomly assigned receive either 3 months MCO-HD followed by high-flux (HF-HD), or vice versa. The primary endpoint was myoglobin reduction ratio (RR) after MCO-HD. Secondary endpoints were the effect on other protein-bound toxins, parameters...
Recent data suggest that the use of medium cut-off (MCO) dialyzers in hemodialysis (HD) promotes greater clearance and reduction ratio (RR) for myoglobin other large-sized molecules than on-line hemodiafiltration (ol-HDF), but its effects on β2-microglobulin are not clear. We compared RR clearances small middle-sized between high-flux ol-HDF MCO (Theranova) dialyzer HD (MCO-HD) as well nutritional parameters.We retrospectively analyzed 10 patients treated first with who were thereafter...
ABSTRACT Background Autosomal dominant polycystic kidney disease (ADPKD) is associated with an increased risk for developing intracranial aneurysms (IAs). We aimed to evaluate the frequency of diagnosis IAs in cross-sectional, population-based, Genkyst cohort, describe ADPKD-associated and analyse factors occurrence ADPKD patients. Methods A cross-sectional study was performed 26 nephrology centres from western part France. All patients underwent genetic testing PKD1/PKD2 other cystogenes....
The health safety conditions governing the practice of online hemodiafiltration (OL-HDF) do not yet incorporate risks related to presence endocrine disruptors such as bisphenol A (BPA). aim this study was assess, for first time, exposure BPA but also its chlorinated derivatives (ClxBPA) (100 times more estrogenic than BPA) during OL-HDF. We demonstrated that is transmitted by different medical devices used in OL-HDF: ultrafilters, dialysis concentrate cartridges (and only dialyzers,...
Online hemodiafiltration (OL-HDF) and hemodialysis (HD) using high-performance membranes such as adsorptive, medium cut-off (MCO), super high-flux (SHF) dialyzers have been implemented to enhance the removal of middle molecules (MM). The aim this study was compare efficacy different dialysis strategies on small solutes MM reduction ratio (RR) mass removal.We performed a prospective in 8 HD patients. Each patient underwent 9 sessions: seven sessions either Theranova 500™, Elisio 21H™, Renak...
Patients with end stage kidney disease treated by dialysis (ESKDD) process sessions to remove molecules usually excreted kidneys. However, therapy could also contribute endocrine disruptors (ED) burden. Indeed, materials like dialyzer filters, ultrapure dialysate and replacement fluid exposed ESKDD patients Bisphenol A (BPA) chlorinated derivatives of BPA (ClxBPAs). Thus, our aim was compare ClxBPAs exposure between patients, 5 chronic (CKD5) not dialyzed healthy volunteers. Then we describe...
Low-molecular weight heparins (LMWH) are widely used for preventing clotting during hemodialysis (HD). Although injection in the venous blood line is recommended to avoid initial loss of LMWH through dialyzer, still frequently administered arterial at start dialysis. This study aimed compare safety and efficacy same enoxaparin dose or line. We also evaluated antifactor Xa (aXa) activity according route dialysis modalities: high-flux (HF) HD, medium cut-off (MCO) online hemodiafiltration...
RESULTS:TheranovaV R was well accepted by all the patients and no adverse events were reported.The main results, reported in table 1, showed a high removal rate for uremic toxins analyzed.The albumin level measured before after study protocol without changes (3,8360,3 vs 3,8360,3 g/dl, p=0,999).Comparing our results obtained with TheranovaV filter HD data previous on infusion management mode HDF postdilution (see Table 2, *HDF online derived Teatini et al Blood Purification 2011;31:259-267),...
Belmouaz, Mohamed; Goussard, Guillaume; Joly, Florent; Thomas, Betous; Bridoux, Frank Author Information