A5089078972- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Assisted Reproductive Technology and Twin Pregnancy
- Organ Donation and Transplantation
- Renal Transplantation Outcomes and Treatments
- Alcohol Consumption and Health Effects
- Prenatal Screening and Diagnostics
- Substance Abuse Treatment and Outcomes
- Ovarian function and disorders
- Transplantation: Methods and Outcomes
- Pregnancy and preeclampsia studies
- Blood Coagulation and Thrombosis Mechanisms
- Renal and Vascular Pathologies
- Reproductive Health and Technologies
- Statistical Methods and Inference
- Hepatitis C virus research
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular Function and Risk Factors
- Palliative Care and End-of-Life Issues
- Nitric Oxide and Endothelin Effects
- Cardiac Imaging and Diagnostics
- Ectopic Pregnancy Diagnosis and Management
- Cytomegalovirus and herpesvirus research
- Maternal and fetal healthcare
Agence de la Biomédecine
2009-2023
Assistance Publique – Hôpitaux de Paris
1998-2021
Hôpital Jean-Verdier
2021
Beth Israel Deaconess Hospital
2010
Beth Israel Deaconess Medical Center
2010
Harvard University
2010
Dana-Farber/Harvard Cancer Center
2010
Établissement Français du Sang
2003-2005
Hôpital Beaujon
1995-2004
Inserm
1991-2001
Characteristics and outcomes of recent portal or mesenteric venous thrombosis are ill-known. We intended to compare these features with those patients cavernoma, also assess the incidence recanalization on anticoagulation therapy. All seen between 1983 1999 were enrolled into this retrospective study if cavernoma had been documented, cancer liver, pancreas, bile duct, intrahepatic block including cirrhosis, obstruction hepatic veins ruled out. The proportion was 7% in before 1990 56% after...
Abstract STUDY QUESTION What are the reported data on cycles in ART, IUI and fertility preservation (FP) interventions 2016 as compared to previous years, well main trends over years? SUMMARY ANSWER The 20th ESHRE report ART shows a progressive increase treatment cycle numbers Europe, with decrease number of transfers more than one embryo causing reduction multiple delivery rates (DR), higher pregnancy DR after frozen replacement (FER) fresh IVF ICSI cycles, while outcomes for remained...
What are the European trends and developments in ART IUI 2015 as compared to previous years?The 19th ESHRE report on shows a continuing expansion of treatment numbers Europe, this increase, variability modalities rising contribution birth rates most participating countries all point towards increasing impact society.Since 1997, data generated by national registries have been collected, analysed reported 18 manuscripts published Human Reproduction.Collection IVF-Monitoring Consortium (EIM)...
The role of alcohol intake in the occurrence severe liver disease chronic hepatitis C virus (HCV) carriers is still debated. A cross-sectional study has been conducted 233 carriers. Weekly self-reported consumption (SRAC) was evaluated, serum HCV RNA levels were measured by a branched DNA technique (Quantiplex 2.0) and genotypes determined. biopsy performed simultaneously lesions graded with Knodell histological activity index. Data examined uni- multivariate analyses. Alcohol relatively low...
Outpatients followed in an alcoholic clinic and who fulfilled DSM-III-R criteria for alcohol dependence had used both tobacco (at least one cigarette every day) the preceding week were studied. For each patient, two experimenters assessed: (1) amount of used; (2) severity product. Results showed that: (a) The prevalence smoking this population current dependents was 88%; (b) 91.6% sample smoker alcoholics dependent on nicotine; (c) smoked correlated to consumed dependence; (d) there a...
Abstract: Aim: To evaluate 5‐year survival predictive factors in hospitalised patients with excessive alcohol intake and cirrhosis, including a multivariate analysis the severity of liver disease, gastrointestinal bleeding, concomitant viral B or C infection, smoking status, presence alcoholic hepatitis at inclusion abstinence from during follow‐up. Methods: In non‐concurrent cohort study, 122 cirrhosis were followed up least five years till death. Two lost to Results: The rates 43% 66%, 50%...
Post-transplant lymphoproliferative disorders (PTLD) are a rare but serious complication after organ transplantation. A French Registry of PTLD was set up in nationwide population kidney transplant recipients. We prospectively enrolled all adult recipients developing between January 1, 1998, and December 31, 2003. analyzed the incidence, risk prognostic factors by Kaplan-Meier Cox analyses. Totally 230 cases were referred to Registry. Cumulative incidence 1.18% 5 years. Older age (per year,...
A possible hepatotoxicity of cigarette smoke has been recently suggested by epidemiological and experimental studies. Our aim was to study the relationships between smoking liver fibrosis activity in patients with chronic hepatitis C. cross-sectional performed a group 310 C consecutively hospitalized for their first biopsy. The age, gender, alcohol consumption, route contamination, tobacco Knodell scores were examined univariate, age-adjusted, multivariate analyses. One hundred seventy-six...
The results of the transplantation marginal donor kidneys remain controversial. This study aimed to investigate impact risk factors as predictors kidney-graft outcome.Allograft failure were studied in 7,209 cadaveric kidney-transplant recipients reporting Etablissement français des Greffes (EfG) from 1996 2000, which 544 (7.6%) donors aged over 60. Both univariate and multivariate analysis used assess effect stratified according recipient age.Overall graft survival was 91.1% (95% confidence...
Background To the best of our knowledge, no study has exhaustively evaluated association between maternal morbidities and Coronavirus Disease 2019 (COVID-19) during first wave pandemic in pregnant women. We investigated, natural conceptions assisted reproductive technique (ART) pregnancies, whether were more frequent women with COVID-19 diagnosis compared to without pandemic. Methods findings conducted a retrospective analysis prospectively collected data national cohort all hospitalizations...
Abstract Background and Aim: Terlipressin has been proposed to treat renal failure in patients with type 1 hepatorenal syndrome (HRS). However, the predictive factors for improved function survival are unknown HRS treated terlipressin. The aim of present retrospective study was investigate prognosis Methods: clinical charts 18 consecutive cirrhosis terlipressin were studied. identified using univariate analyses. Results: Improved function, indicated by a significant decrease serum creatinine...
Abstract: Background: In patients with cirrhosis, refractory ascites is associated a poor prognosis and an indication for liver transplantation. However, factors that determine remain unclear. Aims: To investigate the predictive of in ascites. Methods: Seventy‐five were followed‐up 18±13 months (mean±SD) survival was analyzed. Results: The 1‐year probability 52%. Univariate analyses showed older patients, hepatocellular carcinoma diabetes, all assessed at entry, significantly increased risk...
Abstract: Background: In patients with cirrhosis, severe sepsis may stimulate the extrinsic coagulation pathway resulting in thrombin generation and fibrin formation. Aims: To compare 23 to 13 infected without 18 infection. Methods: Zymogen forms of clotting factors involved (i.e., VII+X, V, prothrombin), presence soluble were assessed. Results: significantly lower, while Child–Pugh score proportion higher severe‐sepsis group than other groups. Decreased zymogen levels independently...
We prospectively evaluated the institutional variability in perioperative transfusion therapy orthotopic liver transplantation (OLT). Adult OLTs completed during a 12-mo period were studied until 48th postoperative hour at 8 centers. A multivariate analysis using mixed-effects logistic regression included variables predisposing to blood loss and center random effect. In addition, influence of calculated hemoglobin (Hb) on individual probability receiving red cells (RBCs), fresh frozen plasma...
Does the endometrial preparation protocol (artificial cycle (AC) vs natural (NC) stimulated (SC)) impact risk of early pregnancy loss and live birth rate after frozen/thawed embryo transfer (FET)?In FET, ACs were significantly associated with a higher lower compared SC or NC.To date, there is no consensus on optimal in terms outcomes. Although some studies have reported using AC NC SC, significant difference was found concerning rate. Furthermore, study has three protocols large population.A...
A simple model, containing the proportional hazards regression model as a special case, is presented. The purpose of to provide framework in which specific alternatives assumption may be tested. Rank-invariant score tests for linear, quadratic, or exponential trends can, instance, all undertaken within this framework. In case two-sample problem required calculations are shown take particularly form. Special consideration given there an inversion effect, i.e., where hazard functions cross at...
Epidemiological studies suggest that singletons born from assisted reproductive technologies (ART) have a high risk of adverse perinatal outcomes, specifically for imprinting disorders. Because ART processes take place at times when epigenetic reprogramming/imprinting are occurring, there is concern can affect genomic imprints. However, little currently known about the defects according to type or underlying female infertility. From French national health database, cohort 3,501,495 over...