Alexander Simidchiev

ORCID: 0000-0003-4643-9388
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About
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Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Air Quality and Health Impacts
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Air Quality Monitoring and Forecasting
  • Global Health Care Issues
  • Climate Change and Health Impacts
  • Respiratory and Cough-Related Research
  • Asthma and respiratory diseases
  • Vehicle emissions and performance
  • Inhalation and Respiratory Drug Delivery
  • Salivary Gland Disorders and Functions
  • Parasitic infections in humans and animals
  • Health Systems, Economic Evaluations, Quality of Life
  • Sarcoidosis and Beryllium Toxicity Research
  • Cardiovascular Effects of Exercise
  • Respiratory viral infections research
  • Foreign Body Medical Cases
  • Esophageal and GI Pathology
  • Pulmonary Hypertension Research and Treatments
  • Health Promotion and Cardiovascular Prevention
  • Chronic Disease Management Strategies
  • Immunodeficiency and Autoimmune Disorders
  • COVID-19 Pandemic Impacts
  • COVID-19 epidemiological studies
  • Allergic Rhinitis and Sensitization

Ministry of Interior
2020-2024

Medical University Plovdiv
2021

Lozenetz Hospital
2020

GlaxoSmithKline (Canada)
2016-2017

Introduction: Pulmonary fibrosis includes a spectrum of diseases and is incurable. There variation in disease course, but it often progressive leading to increased breathlessness, impaired quality life, decreased life expectancy. Detection pulmonary challenging, which contributes considerable delays diagnosis treatment. More knowledge about the diagnostic journey from patients' perspective needed improve pathway. The aims this study were evaluate time fibrosis, identify potential reasons for...

10.3389/fmed.2021.711194 article EN cc-by Frontiers in Medicine 2021-08-04
Mohammad A. Alsayegh Hanan Alshamali Mousa Khadada A Ciccolini Anne K. Ellis and 95 more Diana Quint William Powley Laurie Lee Yahya Fiteih Shairaz Baksh Harissios Vliagoftis Sebastien K. Gerega Brad Millson Katia Charland Stéphane Barakat Xichun Sun Ricardo Jimenez Susan Waserman Mark J. Fitzgerald Jacques Hébert Josiane Cognet-Sicé Kevin E. Renahan Saiful Huq Rishma Chooniedass Scott Sawyer Hans Pasterkamp Allan B. Becker Steven G. Smith Shi‐Yuan Zhang K. M. P. D. Jayasundara Claire E. Tacon Alexander Simidchiev Gilbert Nadeau Necdet B. Gunsoy Hana Müllerová Frank C. Albers Young Woong Kim Casey P. Shannon Amrit Singh Helen Neighbour Mark Larché Scott J. Tebbutt Annika Klopp Lorena Vehling Allan B. Becker Padmaja Subbarao Piush J. Mandhane Stuart E. Turvey Malcolm R. Sears Meghan B. Azad Keely Loewen Barret A. Monchka Salaheddin M. Mahmud Geert ‘t Jong Cristina Longo Gillian Bartlett Francine M. Ducharme Tibor Schuster Brenda MacGibbon Tracie A. Barnett Michelle L. North Jeff Brook Elizabeth Lee Vanessa Omana Jenny Thiele Lisa M. Steacy Greg J. Evans Miriam L. Diamond Gordon Sussman Yann Amistani Kathy Abiteboul Mark W. Tenn Chenxi Yang Christopher Carlsten Edward M. Conway Douglas P. Mack Rofina Yasmin Othman Colin Barber Chrystyna Kalicinsky Andrea E. Burke Mary Messieh Parameswaran Nair Tae‐Wook Chun Lindsay Douglas Joel Liem Lucy Duan Charlotte Miller Pascale Dupuis Lori Connors Michael Fein Joseph Shuster Hani Hadi Brooke I. Polk Nikita Raje Roxane Labrosse Philippe Bégin Louis Paradis Anne Des Roches Jonathan Lacombe‐Barrios Sanju Mishra

Background: Multiple animal antigens, spores and pollens were collected identified from the Kuwaiti atmosphere.The role for these antigens in mediating allergic rhinitis residents needs to be evaluated.Objective: To investigate causes (both indoors outdoors) of residents.Method: This is a retrospective study all positive skin tests that we obtained our Allergy clinic Mubarak Alkabeer Hospital Kuwait, during period between May 2013 December 2015, patients who presented with symptoms and/or...

10.1186/s13223-017-0192-y article EN cc-by Allergy Asthma and Clinical Immunology 2017-04-07

Background . Chronic obstructive pulmonary disease (COPD) prevalence in Canada has risen over time. COPD-related exacerbations contribute to the increased health care utilization (HCU) this population. This study investigated impact of on HCU. Methods retrospective observational cohort used patient data from Québec provincial insurance databases. Eligible patients with a new HCU claim diagnostic billing for COPD during 2001–2010 were followed until March 31, 2011. Exacerbation rates and time...

10.1155/2017/8184915 article EN cc-by Canadian Respiratory Journal 2017-01-01

Severe asthma is a serious condition with significant burden on patients' morbidity, mortality, and quality of life. Some biological therapies targeting the IgE interleukin-5 (IL5) mediated pathways are now available. Due to lack direct comparison studies, choice which medication use varies. We aimed explore beliefs practices in severe asthma, hypothesizing that differences will occur depending prescribers' specialty experience.We conducted an online survey composed 35 questions English. The...

10.1016/j.waojou.2020.100441 article EN cc-by-nc-nd World Allergy Organization Journal 2020-07-01

<b>Background:</b> Air pollution can be a contributing cause to the development and exacerbation of number chronic conditions, including respiratory, cardiovascular, neurologic endocrine diseases. There is paucity knowledge about acute effects air on emergency services workload related air-pollution in Bulgaria9s capital Sofia. <b>Methods:</b> We conducted retrospective time-series study investigate correlation particulate (particulate matter with an aerodynamic diameter &lt; 10 µm [PM10]...

10.1183/13993003.congress-2020.1300 article EN 2020-09-07

To describe the healthcare burden associated with not escalating patients COPD managed LAMA or LABA monotherapy LAMA/LABA dual therapy to ICS/LAMA/LABA following a moderate severe exacerbation. This observational study utilised medical claims from Quebec Provincial Health Insurance administrative database. Included were ≥40 years of age an incident diagnosis (during 2002–2011) receiving respiratory medicine within 2 weeks claim and treated LAMA, without preceding Multivariate-adjusted...

10.1183/13993003.congress-2016.pa300 article EN 05.01 - Airway pharmacology and treatment 2016-09-01

Abstract We present a clinical case of patient with reactivation SARS-CoV-2 infection after strenuous exercise in the gym. Reactivation virus was confirmed detecting nasopharyngeal swab sample using real-time polymerase chain reaction (PCR). The symptoms – fever and shortness breath, as well presence IgM antibodies further diagnosis. subjective complaints persistent breath for more than few weeks were noted.

10.2478/amb-2020-0033 article EN cc-by-nc-nd Acta Medica Bulgarica 2020-09-01

In modern cities, poor air quality has contributed to replacing motorized cars with active modes of transportation such as cycling.However, when designing and building bike infrastructure, officials neglect consider concerns connected cyclists, most cycling lanes are developed next heavy-traffic roadways.This poses additional health risks due their increased ventilation rate.To preserve a sustainable life for city's residents, it's critical understand how detect quantify PM exposure,...

10.15439/2022f230 article EN cc-by Annals of Computer Science and Information Systems 2022-09-26

Pulmonary fibrosis (PF) is associated with reduction in vital capacity (VC) and increase expiratory flow rates, including peak (PEF). Full pulmonary function testing computed tomography chest scans are limited resources some geographic areas a simple sensitive screening test would be of value. We hypothesized that the ratio % predicted PEF over VC (%PEF/%VC), from spirometry alone might to screen for fibrosis.The %PEF/%VC 1,000 consecutive spirometric volume curves was nearly normally...

10.25011/cim.v44i1.35976 article EN Clinical and investigative medicine 2021-03-21

Abstract: Tracheal stenosis (TS), tracheomalacia, and tracheo-esophageal fistula (TEF) are life-threatening complications, most often caused by long-term mechanical ventilation. We describe a 45-year-old man with combined thoracoabdominal trauma who developed symptoms of TEF TS after 20-day period The diagnostic therapeutic modalities used discussed. Periodic endoscopic inspection the airways all ventilatior patients have tracheostomies may help to prevent and/or detect these complications.

10.1097/00128594-199801000-00010 article EN Journal of Bronchology 1998-01-01
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