Jia Che

ORCID: 0000-0003-4679-3811
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Research Areas
  • Prenatal Screening and Diagnostics
  • MicroRNA in disease regulation
  • Cancer Treatment and Pharmacology
  • Fetal and Pediatric Neurological Disorders
  • RNA modifications and cancer
  • Catalysis for Biomass Conversion
  • Media, Gender, and Advertising
  • Tracheal and airway disorders
  • Nostalgia and Consumer Behavior
  • Hydrological Forecasting Using AI
  • Biological Activity of Diterpenoids and Biflavonoids
  • Consumer Behavior in Brand Consumption and Identification
  • Enzyme-mediated dye degradation
  • Head and Neck Anomalies
  • MRI in cancer diagnosis
  • Polysaccharides and Plant Cell Walls
  • Chemical Reactions and Isotopes
  • Head and Neck Cancer Studies
  • Genetic Syndromes and Imprinting
  • Colorectal Cancer Treatments and Studies
  • Endometrial and Cervical Cancer Treatments
  • Spacecraft and Cryogenic Technologies
  • Biofuel production and bioconversion
  • Enzyme Production and Characterization
  • Reconstructive Surgery and Microvascular Techniques

Nanjing Foreign Language School
2024

Tongde Hospital of Zhejiang Province
2022-2024

Dalian Institute of Chemical Physics
2019-2024

Chinese Academy of Sciences
2019-2024

Third Affiliated Hospital of Zhengzhou University
2022-2024

Sixth Affiliated Hospital of Sun Yat-sen University
2016-2018

Sun Yat-sen University
2016-2018

Xi'an Siyuan University
2015

Qingdao Agricultural University
2015

State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering
2014

Abstract PEAK1 is upregulated in multiple human malignancies and has been associated with tumor invasion metastasis, but little known about the role of colorectal cancer (CRC) progression. We investigated expression pattern, function regulatory mechanisms CRC. Here, we found that overexpressed CRC tissues high predicts poor survival colon not rectal cancer. Functionally, silencing inhibits cell proliferation, migration, vitro growth xenografts nude mice. Mechanistic studies revealed induced...

10.1038/s41419-018-0320-8 article EN cc-by Cell Death and Disease 2018-02-15

5-fluorouracil (5-FU)-based chemotherapy is the main chemotherapeutic approach for colorectal cancer (CRC) treatment. Because chemoresistance occurs frequently and significantly limits CRC therapies, a novel agent needed. Pseudolaric acid B (PAB), small molecule derived from Chinese medicinal herb ''Tujinpi'', exhibits strong cytotoxic effects on variety of cancers. However, detailed mechanisms by which PAB inhibits cell growth its potential role in overcoming 5-FU resistance have not been...

10.1016/j.canlet.2016.09.007 article EN cc-by-nc-nd Cancer Letters 2016-10-07

In the past decades, various studies have suggested a possible link between thymidine phosphorylase (TP) level and colorectal cancer (CRC) treated with 5-fluorouracil (5-FU)-based chemotherapy; however, they arrived at inconsistent results. Therefore, present meta-analysis aimed to disclose more comprehensive evaluation of this relationship. PubMed, Cochrane Library, Ovid MEDLINE, Embase China National Knowledge Infrastructure were systematically searched for that evaluated prognostic value...

10.3892/mco.2017.1436 article EN Molecular and Clinical Oncology 2017-10-03

A tissue microarray (TMA) containing 76 individual colorectal tumor samples and 28 adjacent normal was constructed, the expression levels of LINC01314 miR-96 were detected by fluorescence in situ hybridization. The both upregulated CRC tissues associated with vascular metastasis (p < 0.05). significantly positive correlation observed between 0.001, r = 0.870). Dominant a risk factor for blood vessel invasion 0.05) poor 5-year survival hazard ratio 4.144). Kaplan-Meier analysis indicated that...

10.1155/2022/5378963 article EN cc-by Disease Markers 2022-10-07

To analyze ultrasonographic manifestations and genetic etiology of nine fetuses with 7q11.23 duplication syndrome.

10.3760/cma.j.cn511374-20221117-00795 article EN PubMed 2024-03-10

To explore the pregnancy outcome and postpartum clinical phenotype of LCR22B/C~D central 22q11.2 deletion syndrome.

10.3760/cma.j.cn511374-20221125-00812 article EN PubMed 2024-02-10

Background Lung adenocarcinoma (LUAD) stands as a major respiratory malignancy with high mortality. With the advent of immunotherapy, new therapeutic avenues have emerged in cancer treatment. Objective Our focus aimed at developing CD8 + T cell-based immune gene prognostic model (CDIGPM) for LUAD, shedding light on immunological aspects and potential advantages immunotherapy distinct CDIGPM-defined LUAD categories. Methods Data from patients were extracted TCGA GEO databases (GSE11969). The...

10.1177/18758592241296764 article EN Cancer Biomarkers 2024-12-01

In the rapidly evolving landscape of modern brand marketing, traditional brands are tasked with intricate challenge melding their storied cultural heritage innovative digital strategies. This research delves into marketing tactics White Rabbit Creamy Candy, an iconic Chinese snack deeply rooted in historical and emotional narratives. The study illuminates distinctiveness market by exploring its significance, symbols, resonance. Employing a comprehensive framework, investigation uncovers...

10.54254/2754-1169/57/20230779 article EN cc-by Advances in Economics Management and Political Sciences 2024-01-04

Recent decades have seen the expansion of indications for partial laryngectomy. This study focused on application horizontovertical laryngectomy T2 and selected T3 T4 supraglottic carcinomas. An osteomuscular flap was designed to reconstruct laryngeal defect preserve all essential functions. Seventy-six patients treated between November 1979 October 1990 were reviewed retrospectively. All but two followed up at least 5 years. There 11 cases T2, 57 T3, 8 tumors. The survival rates 7 stage II,...

10.1016/s0194-5998(97)70187-6 article EN Otolaryngology 1997-09-01
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