Andreas Tsakalof

ORCID: 0000-0003-4702-0394
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About
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Research Areas
  • Building materials and conservation
  • Pesticide Exposure and Toxicity
  • Effects and risks of endocrine disrupting chemicals
  • Conservation Techniques and Studies
  • Cancer, Hypoxia, and Metabolism
  • Analytical Chemistry and Chromatography
  • Cultural Heritage Materials Analysis
  • Vitamin D Research Studies
  • Pesticide Residue Analysis and Safety
  • Toxic Organic Pollutants Impact
  • Surface Modification and Superhydrophobicity
  • Environmental Toxicology and Ecotoxicology
  • Advanced Chemical Sensor Technologies
  • Pesticide and Herbicide Environmental Studies
  • Insect and Pesticide Research
  • Phytochemicals and Antioxidant Activities
  • Mass Spectrometry Techniques and Applications
  • Metabolomics and Mass Spectrometry Studies
  • Carcinogens and Genotoxicity Assessment
  • Forensic Toxicology and Drug Analysis
  • Analytical Methods in Pharmaceuticals
  • Analytical chemistry methods development
  • Air Quality and Health Impacts
  • Pharmacological Effects of Medicinal Plants
  • Animal Ecology and Behavior Studies

University of Thessaly
2015-2024

University of Crete
1994-2024

University Hospital of Larissa
2020-2021

RMIT University
2015

Ormylia Foundation
2002-2011

Aristotle University of Thessaloniki
2008

University of Surrey
1995

Hydrophilic silica (SiO2) nanoparticles were dispersed in solutions of poly(methyl methacrylate) (PMMA) and a commercial poly(alkyl siloxane) (Rhodorsil 224), the suspensions sprayed on glass surfaces. The effect particle concentration hydrophobic character PMMA−SiO2 Rhodorsil−SiO2 films was investigated showed following: (i) Static contact angles (θs), measured surfaces that prepared from dilute dispersions (particle <1% w/v), increase rapidly with reach maximum values (154 164° for...

10.1021/la801817e article EN Langmuir 2008-08-23

The aim of the present study was to investigate ability breath analysis distinguish lung cancer (LC) patients from with other respiratory diseases and healthy people. population sample consisted 51 confirmed LC, 38 pathological computed tomography (CT) findings not diagnosed 53 controls. concentrations 19 volatile organic compounds (VOCs) were quantified in exhaled participants by solid phase microextraction (SPME) VOCs subsequent gas chromatography-mass spectrometry (GC-MS) analysis....

10.3390/metabo10080317 article EN cc-by Metabolites 2020-08-03

In this study, the content composition and antioxidant activity of goji berry fruits from two species (Lycium barbarum Lycium chinense) were assessed. The total carbohydrate phenolic contents evaluated using attenuated reflection Fourier-transform infrared (ATR-FT-IR) spectroscopy, while was examined with in vitro methods, which are based on scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH•) 2,2'-azino-bis(3-ethyl-benzthiazoline-sulfonic acid) (ABTS•⁺) free radicals. fatty-acid profile...

10.3390/antiox8030060 article EN cc-by Antioxidants 2019-03-10

The iron-chelator desferrioxamine (DFO) and the transition metal cobalt induce hypoxia-inducible factor-1α (HIF-1α) in normoxia. DFO stabilizes HIF-1α from proteolysis by inhibiting activity of iron-dependent prolyl hydroxylases, but mechanism action is not fully elucidated. purpose this study was to examine regulation induction HeLa cell proliferation role iron these processes. Our results show that, unlike DFO, transcriptionally active CoCl2 cannot be abrogated addition excess Fe3+,...

10.1080/10715760600730810 article EN Free Radical Research 2006-01-01

The aim of this study was to assess the antioxidant and antimutagenic activities ultrasound assisted aqueous extracts from dry goji berry fruits cultivated in Greece. extracts' free radical scavenging activity assessed by DPPH ABTS+ assays. results both assays demonstrated that exhibited strong with IC50 values ranging 1.29 3.00 mg/ml for 0.39 1.10 mg/mL assay. investigated also inhibited radical-induced DNA damage induced peroxyl (ROO) radicals 0.69 6.90 mg/mL. Τhe extract highest potency...

10.1016/j.toxrep.2018.02.001 article EN cc-by-nc-nd Toxicology Reports 2018-01-01

Abstract A RP‐HPLC method was developed for the assessment of caffeine and its metabolites in urine used evaluation CYP1A2, CYP2A6, xanthine oxidase (XO) N ‐acetyl‐transferase‐2 (NAT‐2) vivo activities 44 Greek volunteers (21 men, 23 women). Spot samples were analyzed 6 h after 200 mg consumption, following a 30 methylxantine‐free diet. The major urinary are 1‐methyluric acid (1U), 5‐acetylamino‐6‐formylamino‐3‐methyluracil (AFMU), 1‐methylxanthine (1X), 1,7‐dimethyluric (17U)...

10.1002/bmc.736 article EN Biomedical Chromatography 2007-01-15

The decrease of surface energy mineral substrates similar to those used in many stone monuments cultural heritage by the application protective polymer coatings along with simultaneous increase their roughness can ability repel water substantially. In this work, effect artificially induced on repellency coated films was investigated. Natural marble samples or home made calcium carbonate blocks were tried as substrates. achieved chemical etching creation nanoscale binary composition film...

10.1088/1742-6596/61/1/269 article EN Journal of Physics Conference Series 2007-04-01

&lt;b&gt;&lt;i&gt;Background/Aim:&lt;/i&gt;&lt;/b&gt; An alarming increase in vitamin D deficiency even sunny regions highlights the need for a better understanding of genetic background endocrine system and molecular mechanisms gene polymorphisms receptor (VDR). In this study, serum levels 25(OH)D&lt;sub&gt;3&lt;/sub&gt; were correlated with common VDR (&lt;i&gt;ApaI, BsmI, FokI&lt;/i&gt;, &lt;i&gt;TaqI&lt;/i&gt;) 98 subjects Greek homogeneous rural population....

10.1159/000514338 article EN cc-by-nc-nd Lifestyle Genomics 2021-01-01

The Legionella colonization frequency at 385 Greek hotel hot and cold water distribution systems was 20.8%. contamination associated with the presence of an oil heater (odds ratio [OR]=2.04, 95% confidence interval [CI]=1.12 to 3.70), sample temperature (OR=0.26, CI=0.1 0.5), seasonal operation (OR=3.23, CI=1.52 6.87), independent disinfection system (OR=0.30, CI=0.15 0.62). same temperatures, free-chlorine levels, pHs differently affect survival various spp.

10.1128/aem.02191-06 article EN Applied and Environmental Microbiology 2007-01-20

To evaluate the exposure of different population groups in Thessaly (Greece) to organophosphate pesticides (OPs) and investigate dependence levels on pesticide application practices, personal protective hygienic measures taken.For assessment, four dialkyl phosphate (DAP) metabolites were quantified spot urine samples 77 sprayers, 75 residents studied agricultural area non-involved activities 112 urban who served as a control group. Structured questionnaires used record demographic...

10.1136/oemed-2013-101490 article EN Occupational and Environmental Medicine 2013-11-01

Methotrexate (MTX) is a dihydrofolate reductase inhibitor that used for the treatment of tumors and autoimmune diseases. Several automated binding assays are in clinical practice numerous chromatographic methods have been developed toward higher specificity sensitivity. In present study, phenyl cartridges were solid-phase extraction (SPE) MTX from human serum samples; subsequently, extracts analyzed by reversed-phase high-performance liquid chromatography. Isocratic separation was...

10.1093/chromsci/bmt081 article EN Journal of Chromatographic Science 2013-06-25

Abstract Popularity of goji berry fruit extracts as functional ingredients is growing rapidly. “Green” aqueous extraction technologies are preferable to organic solvent‐based processes they improve the bioactivity and added value these extracts. This work aimed at optimizing ultrasound assisted (UAE) Lycium barbarum for both locally produced imported fruits comparing in relation conditions origin fruits, using a response surface model. The optimal solvent/extracted material ratio,...

10.1111/jfpe.12522 article EN Journal of Food Process Engineering 2016-12-14
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