Govind Gupta

ORCID: 0000-0003-4703-418X
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Graphene and Nanomaterials Applications
  • Advanced Nanomaterials in Catalysis
  • Conducting polymers and applications
  • Microplastics and Plastic Pollution
  • Legume Nitrogen Fixing Symbiosis
  • Supercapacitor Materials and Fabrication
  • Plant-Microbe Interactions and Immunity
  • Advanced Photocatalysis Techniques
  • Heavy Metal Exposure and Toxicity
  • Ga2O3 and related materials
  • Graphene research and applications
  • Advanced Sensor and Energy Harvesting Materials
  • Mercury impact and mitigation studies
  • GaN-based semiconductor devices and materials
  • Analytical Chemistry and Sensors
  • Semiconductor materials and devices
  • Electrochemical Analysis and Applications
  • Inflammasome and immune disorders
  • Electrochemical sensors and biosensors
  • Air Quality and Health Impacts
  • Polymer-Based Agricultural Enhancements
  • Nematode management and characterization studies
  • Computational Drug Discovery Methods
  • Neonatal Respiratory Health Research

Swiss Federal Laboratories for Materials Science and Technology
2023-2024

Council of Scientific and Industrial Research
2017-2024

Academy of Scientific and Innovative Research
2020-2024

University of St. Gallen
2024

Indian Institute of Technology Kanpur
2018-2024

Karolinska Institutet
2020-2023

CSIR National Physical Laboratory of India
2023

National Physical Laboratory
2023

Advanced Materials and Devices (United States)
2016-2019

Chhatrapati Shahu Ji Maharaj University
2019

Graphene oxide (GO) is a promising and remarkable nanomaterial that exhibits antimicrobial activity due to its specific surface–interface interactions. In the present work, for first time, we have reported antibacterial of GO-coated surfaces prepared by two different methods (Hummers' improved, i.e., GOH GOI) against bacterial biofilm formation. The toxicity deposited was investigated both Gram-negative (Escherichia coli) Gram-positive (Staphylococcus aureus) models bacteria. mechanism...

10.1021/acsomega.7b00371 article EN publisher-specific-oa ACS Omega 2017-07-03

In this work, the fabrication of MoS2-Polyaniline (PANI) nanocomposites, by in situ polymerization, has been described and its application as a photocatalyst for degradation organic pollutants such methylene blue (MB) 4-chlorophenol (4-CP), reported. The disadvantages MoS2 poor electronic conductivity agglomeration between nanosheets, was overcome intercalating 2D layers with 1D conducting polymer, Polyaniline (PANI). composite material characterised SEM, TEM, BET, XRD, FTIR, UV–Vis...

10.1007/s40089-019-0267-5 article EN cc-by International nano letters. 2019-03-02

Copper oxide (CuO) nanoparticles (NPs) are known to trigger cytotoxicity in a variety of cell models, but the mechanism death remains unknown. Here we addressed macrophages exposed CuO NPs versus copper chloride (CuCl2).The mouse macrophage line RAW264.7 was used as an vitro model. Particle uptake and cellular dose Cu were investigated by transmission electron microscopy (TEM) inductively coupled plasma mass spectrometry (ICP-MS), respectively. The deposition lysosomes isolated from also...

10.1186/s12989-022-00467-w article EN cc-by Particle and Fibre Toxicology 2022-05-10

The growing nanoparticulate pollution (e.g. engineered nanoparticles (NPs) or nanoplastics) has been shown to pose potential threats human health. In particular, sensitive populations such as pregnant women and their unborn children need be protected from harmful environmental exposures. However, developmental toxicity prenatal exposure particles is not yet well studied despite evidence of particle accumulation in placenta. Our study aimed investigate how copper oxide NPs (CuO NPs; 10–20 nm)...

10.1016/j.envint.2023.108015 article EN cc-by Environment International 2023-06-07

The neurotoxicity of hard metal-based nanoparticles (NPs) remains poorly understood. Here, we deployed the human neuroblastoma cell line SH-SY5Y differentiated or not into dopaminergic- and cholinergic-like neurons to study impact tungsten carbide (WC) NPs, WC NPs sintered with cobalt (Co), Co versus soluble CoCl2. salt triggered a dose-dependent cytotoxicity an increase in cytosolic calcium, lipid peroxidation, depletion glutathione (GSH). also suppressed peroxidase 4 (GPX4) mRNA protein...

10.1096/fj.201902191rr article EN The FASEB Journal 2020-02-14

In the current study, we have developed a lightweight nanocomposite biofertilizer (NCB) consisting of physical mixture acylated homoserine lactone (AHL)-coated Fe-carbon nanofibers (Fe-CNFs) and bacterial (Panebacillus polymyxa) endospores immobilized in activated carbon beads. AHL/Fe-CNF is translocated to plants via apoplastic movement through roots shoots leaves, while are retained soil, augmenting plant growth siderophore indole acetic acid production. We tested NCB on leguminous (Cicer...

10.1021/acsagscitech.1c00039 article EN ACS Agricultural Science & Technology 2021-04-22

Abstract There is an urgent need to apply effective, data-driven approaches reliably predict engineered nanomaterial (ENM) toxicity. Here we introduce a predictive computational framework based on the molecular and phenotypic effects of large panel ENMs across multiple in vitro vivo models. Our methodology allows for grouping multi-omics combined with robust toxicity tests. Importantly, identify mRNA-based markers extensively replicate them independent datasets. We find that models...

10.1038/s41467-022-31609-5 article EN cc-by Nature Communications 2022-07-01

Exposure to nanoparticles (NPs) in pregnancy is increasingly linked adverse effects on embryo-fetal development and health later life. However, the developmental toxicity mechanisms of NPs are largely unknown, particular potential placental secretome, which orchestrates many processes pivotal for success. This study demonstrates extensive material- stage-specific deregulation signaling from a single exposure human explants physiologically relevant concentrations engineered (silica (SiO

10.1002/advs.202401060 article EN cc-by Advanced Science 2024-05-20

The increasing applications of engineered nanomaterials (ENMs) in consumer products warrant a careful evaluation their trophic transfer and consequent ecological impact. In the present study, laboratory scale aquatic microbial food chain was established using bacteria (Escherichia coli (E. coli)) as prey ciliated protozoan (Paramecium caudatum) predator organism to determine impact cadmium telluride quantum dots (CdTe QDs). We observed that 29% bacterivory potential paramecium lost,...

10.1021/acs.est.6b03950 article EN Environmental Science & Technology 2017-01-10

AHL/Fe-CNF nanocomposites were effective in increasing germination rate and plant growth as well developing resistance towards biotic abiotic stresses.

10.1039/c9en00199a article EN Environmental Science Nano 2019-01-01

Carbon nanotubes (CNTs) have been extensively investigated, and several studies shown that multi-walled CNTs can trigger inflammation fibrosis in animal models. However, while neutrophils are involved inflammation, most vitro addressed macrophages. Here we explored the impact of three MWCNTs with varying morphology (i.e. long rigid versus short and/or tangled) on primary human macrophages macrophage-differentiated THP-1 cells neutrophil-differentiated HL-60 cells. We found triggered...

10.1080/17435390.2021.1988171 article EN cc-by-nc-nd Nanotoxicology 2021-10-16

Abstract Numerous studies have addressed the biological impact of graphene‐based materials including graphene oxide (GO), yet few focused on long‐term effects. Here, RNA sequencing is utilized to unearth responses human lung cells GO. To this end, BEAS‐2B cell line derived from normal bronchial epithelium subjected repeated, low‐dose exposures GO (1 or 5 µg mL −1 ) for 28 days equivalent, cumulative amount 48 h. Then, samples are analyzed by using NovaSeq 6000 system followed pathway...

10.1002/smll.201907686 article EN cc-by-nc Small 2020-03-29

Fe-CNF/Mo-MOF releases Mo and Fe in soil upon degradation by resident rhizobacteria translocates the micronutrients to plant roots, shoots, leaves.

10.1039/d3en00833a article EN Environmental Science Nano 2024-01-01

Abstract Nano titanium dioxide (nTiO 2 ) is the most abundantly released engineered nanomaterial (ENM) in aquatic environments. Therefore, it prudent to assess its fate and effects on lower trophic-level organisms food chain. A predator-and-prey-based laboratory microcosm was established using Paramecium caudatum Escherichia coli evaluate of nTiO . The surface interaction with E. significantly increased after addition into microcosm. This favoured hetero-agglomeration co-sedimentation extent...

10.1038/srep31422 article EN cc-by Scientific Reports 2016-08-17

Abstract Chromium oxide (Cr 2 O 3 ) nanoparticles (NPs) are being increasingly used as a catalyst for aromatic compound manufacture, abrading agents and pigments (e.g., Viridian). Owing to increased applications, it is important study the biological effects of Cr NPs on human health. The lung one main exposure routes nanomaterials; therefore, present was designed determine genotoxic apoptotic effect in epithelial cells (A549). also elucidated molecular mechanism its toxicity. led DNA damage,...

10.1002/jat.3174 article EN Journal of Applied Toxicology 2015-06-18

Abstract A facile and eco‐friendly synthesis of polypyrrole from monomer pyrrole using nominal amount ferric chloride hexahydrate (FeCl 3 .6H 2 O) oxidant in aqueous solution by chemically oxidative polymerization method has been reported. The use solvent salt have an route favorable for the production large quantities. synthesized samples exhibit good electrical conductivity (2 S/cm) yield 80% reaction time 8 hr at 5°C. Quality properties thoroughly investigated with varying temperature...

10.1002/app.49566 article EN Journal of Applied Polymer Science 2020-06-27
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