A5101529622- Prenatal Screening and Diagnostics
- Genomic variations and chromosomal abnormalities
- Heat Transfer Mechanisms
- Turbomachinery Performance and Optimization
- Fetal and Pediatric Neurological Disorders
- Multiferroics and related materials
- Genomics and Phylogenetic Studies
- Fluid Dynamics and Turbulent Flows
- Microwave Engineering and Waveguides
- Chromosomal and Genetic Variations
- Ferroelectric and Piezoelectric Materials
- Electromagnetic Simulation and Numerical Methods
- Computational Fluid Dynamics and Aerodynamics
- Renal Transplantation Outcomes and Treatments
- Genetics and Neurodevelopmental Disorders
- Metamaterials and Metasurfaces Applications
- Gene expression and cancer classification
- Advanced Multi-Objective Optimization Algorithms
- Aerodynamics and Acoustics in Jet Flows
- Underwater Acoustics Research
- IPv6, Mobility, Handover, Networks, Security
- Power Systems and Technologies
- Energy Efficient Wireless Sensor Networks
- Plant Disease Resistance and Genetics
- Microbial Community Ecology and Physiology
Beihang University
2020-2022
University of Shanghai for Science and Technology
2018
East China University of Science and Technology
2011-2013
Shanghai Center For Bioinformation Technology
2011-2013
China Jiliang University
2008-2011
Beijing University of Posts and Telecommunications
2004
Chongqing University
2000
Background Metagenomics can reveal the vast majority of microbes that have been missed by traditional cultivation-based methods. Due to its extremely wide range application areas, fast metagenome sequencing simulation systems with high fidelity are in great demand facilitate development and comparison metagenomics analysis tools. Results We present here a customizable system: NeSSM (Next-generation Sequencing Simulator for Metagenomics). Combining complete genomes currently available,...
Consideration heat transfer while organizing the flow structure in turbine blade tip region is important to improve aerodynamic performance and reliability. Numerical methods were conducted investigate physics characteristic high pressure squealer tip. The impacts of some geometric parameters conditions on load distribution also discussed. Based above results, a model for was developed. results show that occurred certain mainly caused by leakage jet impingement these surfaces. velocity...
This paper analyzes the magnetoelectric (ME) response around resonance frequency in magnetostrictive/piezoelectric/magnetostrictive (MPM) laminate composites. Following equivalent circuit method and considering mechanical loss, we select nonlinear magnetostrictive constitutive model to present a novel explicit expression for resonant coefficient of Compared with experimental results, predicted ME shows good agreement both qualitatively quantitatively. Also, when electromechanical coupling...
Massively parallel sequencing (MPS) combined with bioinformatic analysis has been widely applied to detect fetal chromosomal aneuploidies such as trisomy 21, 18, 13 and sex chromosome (SCAs) by cell-free DNA (cffDNA) from maternal plasma, so-called non-invasive prenatal testing (NIPT). However, many technical challenges, dependency on correct prediction, large variations of Y measurement high sensitivity random reads mapping, may result in higher false negative rate (FNR) positive (FPR)...
The requirements of future aeroengines challenge turbomachinery designs to be quieter, greener, and more efficient; furthermore, they must developed at considerably reduced cycles costs. Traditional design systems involve the iterative design–evaluation–improvement process, leading high computational costs considerable reliance on expert experience. In this paper, a knowledge-based aerodynamic system consisting experiment framework two-stage modeling is proposed. first phase modeling, deep...
With the development and clinical application of genomics, more concern is focused on single-cell sequencing. In process sequencing, whole genome amplification a key step to enrich sample DNA. Previous studies have compared performance different (WGA) strategies Illumina sequencing platforms, but there no related research aimed at Ion Proton platform, which also popular next-generation platform. Here by amplifying cells from six cell lines with karyotypes, we estimated data features four...
Squealer tip is widely used in turbines to reduce leakage loss. In typical turbine environment, the squealer flow affected by multiple factors such as relative casing motion and wide range of variable incidence angles. The development experimental methods which can accurately model real environment influencing great significance study mechanism. present paper, a low-speed cascade test facility angles (−25° 55°) built. Based on similarity criteria, high-low speed transformation method...
Metagenomic sequence classification is a procedure to assign sequences their source genomes. It one of the important steps for metagenomic data analysis. Although many methods exist, high-throughput in limited time still challenge. We present here an ultra-fast system (MetaBinG) using graphic processing units (GPUs). The accuracy MetaBinG comparable best existing systems and it can classify million 454 reads within five minutes, which more than 2 orders magnitude faster systems. publicly...
Generic propagation model always have accuracy problems. Without calibration, it can hardly be used in practice. This article develops a recursive algorithm on radio calibration for CDMA systems. An evaluation method is introduced and actual drive test results are to verify the refined model's goodness of fit. From seen that this paper feasible
Abstract Background The detection limit of noninvasive prenatal testing (NIPT) by next generation sequencing for any given fetal copy number variants (CNV) can be influenced several factors. In this study, we quantified the effects and predicted value parameters CNVs NIPT. Methods Genomic DNA from patient's leucocytes with 3.16 Mb microdeletion in 22q11.21 was mixed aborted tissues without CNV at various concentrations an enzyme digestion method. Abnormal 0% served as negative control....
The ferromagnetic resonance frequency can be tuned by the external electric field, for magnetoelectric coupling effect of ferrite-piezoelectric laminated composite. In this paper, a novel meander microstrip line filter using composite and is designed optimized. realized dual-stop-band in bias magnetic field or it used mobile communication devices to out two jamming signals with small interval. has device size, high efficiency, low energy consumption noise. It also tune stop-bands at same...
Graft derived cell-free DNA was recently reported as a non-invasive biomarker to detect graft damage or rejection after liver transplantation. There are number of methods for quantification Gcf-DNA, including quantitative-PCR, digital droplet PCR and massively parallel sequencing (next generation sequencing). Here we present the NGS data fragment size distribution in plasma patients with inborn errors metabolism who underwent living-related For more insights please see Analysis DNA:...
Chromosomal aneuploidy, one of the main causes leading to embryonic development arrest, implantation failure, or pregnancy loss, has been well documented in human embryos. Preimplantation genetic testing for aneuploidy (PGT-A) is a test that significantly improves reproductive outcomes by detecting chromosomal abnormalities Next-generation sequencing (NGS) provides high-throughput and cost-effective approach analysis shown clinical applicability PGT-A. Here, we present rapid low-cost...
Chromosomal aneuploidy, one of the main causes leading to embryonic development arrest, implantation failure, or pregnancy loss, has been well documented in human embryos. Preimplantation genetic testing for aneuploidy (PGT-A) is a test that significantly improves reproductive outcomes by detecting chromosomal abnormalities Next-generation sequencing (NGS) provides high-throughput and cost-effective approach analysis shown clinical applicability PGT-A. Here, we present rapid low-cost...
In this paper, the proposed three-port power divider based on four stages cavity, which is different to conventional using coupled transmission line. The design and simulated results show that novel has a good performance, are insert loss 4.77±0.13dB from 690MHz 2.5GHz, return less than −18dB, respectively. addition, performances of demonstrated experimentally. measured well with ones.
OBJECTIVE To analyze the data of non-invasive prenatal testing based on specific loci circulating cell-free fetal DNA (cffDNA). METHODS Selected target chromosomes were analyzed by sequence capture and sequencing. Meanwhile, 600 selected from other for determining concentration cffDNA. RESULTS A total 768 captured 21 18, used to determine whether two abnormal. When minimum detected cffDNA was set at 3% threshold Z score [-6,6], specificity analysis 99.37% sensitivity 100%. CONCLUSION...
Abstract In this paper, the Construction and functions of self-study system for power plant operation is introduced. As a system, it consists two parts, simulator knowledge base. The base has been built by combination expert artificial neural network, which supports with practical experience theoretic knowledge. trainees’ can be improved using system. realization intelligent training function, applications network are mainly introduced in paper.