Time-frequency balanced spectral entropy of electroencephalogram (EEG) and frontal electromyogram (FEMG) is a novel measure hypnosis during anesthesia. Two Entropy parameters are described: Response (RE) calculated from EEG FEMG; State (SE) mainly EEG. This study was performed to validate their performance transition consciousness unconsciousness under different anesthetic agents.Response entropy, SE [S/5 Module, M-ENTROPY (later in text: Entropy), Datex-Ohmeda Division, Instrumentarium...

Background: Recent studies have suggested that electroencephalogram (EEG) bispectral index (BIS) monitoring can improve recovery after anaesthesia and save money by shortening patients’ postoperative stay. We wanted to evaluate the direct costs of BIS measure immediate in patients with or without monitoring. Methods: Eighty undergoing gynaecological surgery were studied. At first, 40 randomized receive either propofol sevoflurane anaesthesia. In these patients, was collected but information...

Background Sevoflurane is suggested as a suitable anesthetic agent for mask induction in adults. The authors recently found that hyperventilation during sevoflurane-nitrous oxide-oxygen associated with cardiovascular hyperdynamic response. We tested the hypothesis response can be explained by electroencephalography (EEG) findings. Methods Thirty women were randomly allocated to receive oxygen-oxygen using single-breath method, followed either spontaneous breathing (n = 15) or controlled 6...

Background: Sevoflurane inhalation induction of anaesthesia is widely used in paediatric anaesthesia. We have found that this method frequently associated with epileptiform electroencephalogram (EEG) adults, especially if controlled hyperventilation used. Methods: assessed EEG during sevoflurane 31 children, aged 2–12 yr. Anaesthesia was induced 8% O 2 N 1:2. The patients were randomized to undergo ventilation (CV group), or breathe spontaneously (SB group) for 5 min. recorded as noninvasive...

Objective: To evaluate electroencephalogram-derived quantitative variables after out-of-hospital cardiac arrest. Design: Prospective study. Setting: University hospital intensive care unit. Patients: Thirty comatose adult patients resuscitated from a witnessed ventricular fibrillation arrest and treated with induced hypothermia (33°C) for 24 hrs. Interventions: None. Measurements Main Results: Electroencephalography was registered the arrival at unit until patient extubated or transferred to...

No validated monitoring method is available for evaluating the nociception/antinociception balance. We assessed surgical stress index (SSI), computed from finger photoplethysmographic waveform amplitudes and pulse-to-pulse intervals, in patients undergoing shoulder surgery under general anesthesia (GA) interscalene plexus block with GA only.In this prospective, randomized study 26 patients, increased blood pressure (BP) or heart rate, movement, coughing were considered to be signs of...

Background This multicenter study evaluated the effect of a new depth anesthesia-monitoring device based on time-frequency-balanced spectral entropy electroencephalogram monitoring (GE Healthcare Finland, Helsinki, Finland) consumption anesthetic drugs and recovery times after anesthesia. Methods The was prospective, randomized, single-blind performed in six hospitals Sweden, Norway. After institutional review board approval written informed consent from each patient, patients were randomly...

Liver transplantation (LT) may be indicated in cirrhotic patients with underlying pulmonary artery hypertension. However, severe hypertension mean pressure (mPAP) above 50 mmHg has even been considered a contraindication to LT. We present patient an mPAP of 56 measured using right heart catheterization (RHC) and severely compromised physical capacity. She was first treated sildenafil (Viagra), potent novel vasodilator, successfully transplanted later. The decreased the level 28-31 her...

Background: Hyperventilation during sevoflurane‐N 2 O‐O mask induction in adults is associated with a hyperdynamic circulatory response and epileptiform electroencephalogram (EEG). We tested the hypothesis that delaying onset of hyperventilation will prevent severe (periodic) EEG response. Methods: Thirty patients were randomized to receive either delayed (group D, n=15) or immediate I, sevoflurane (8% N O 50%) inhalation single‐breath method for unconsciousness. Fifteen allowed breathe...

Background Sevoflurane may induce epileptiform electroencephalographic activity leading to unstable Bispectral Index numbers, underestimating the hypnotic depth of anesthesia. The authors developed a method for quantification during sevoflurane Methods Electroencephalographic data from 60 patients under mask induction were used in analysis. visually classified. A novel electroencephalogram-derived quantity, wavelet subband entropy (WSE), was developed. WSE variables calculated different...

Background It is assumed that the implementation of health information technology introduces new vulnerabilities within a complex sociotechnical care system, but no international consensus exists on standardized format for enhancing collection, analysis, and interpretation technology-induced errors. Objective This study aims to develop classification patient safety incident reporting associated with use mature electronic records (EHRs). also validate by using data set incidents during...

Background: Epileptiform patterns, spikes, polyspikes and periodic epileptiform discharges (PED) have been reported in electroencephalograms (EEGs) during anaesthesia induction with sevoflurane healthy adults children. Published recordings performed a limited number of channels, therefore the topographic distributions these patterns are not known. Methods: Twenty ASA I children aged 4–10 years undergoing routine operations were anaesthetized 8% 50%/50% oxygen nitrous oxide using mask...

Five patients in whom the serum paracetamol levels or amount of ingested was high enough to cause severe liver injury were treated with N ‐acetyl‐cysteine (NAC) and a molecular absorbant recirculating system (MARS). MARS treatment started as early possible order prevent retard development hepatocyte necrosis. Four our five survived without transplantation, one died due brain oedema. The commencement NAC treatments intoxication might give time for regenerate thus avoid transplantation.

Acute liver failure (ALF) and hepatic encephalopathy (HE) can lead to an elevated intracranial pressure (ICP) death within days. The impaired function increases the risks of invasive ICP monitoring, whereas noninvasive methods remain inadequate. purpose our study was explore reliable neuromonitoring for patients with ALF in intensive care unit (ICU) setting; more specifically, we wanted track changes HE predict outcomes treated albumin dialysis. included 20 severe at admission who had been...

The large inspired concentration of sevoflurane (S) during mask induction anesthesia can induce epileptiform electroencephalogram (EEG) associated with tachycardia. Tachycardia is also seen when the desflurane (D) abruptly increased. It not known whether this EEG similar to S. We studied and heart rate (HR) rapidly increased concentrations S or D in 31 females postintubation period anesthesia. Anesthesia was induced propofol remifentanil, tracheas were intubated. Patients randomized receive...

The shortage of anesthesiologists in Finland is worsening. A survey was carried out 2003 among head and nurses to clarify current practice the potentials for reorganizing tasks between anesthesia nurses. national working group analyzed results.A questionnaire concerning doctor nurse resources anesthesiology, allocation tasks, opinions on how these could be reallocated sent 87 32 45 different hospitals. answers from doctors were compared.The response rate 87% 100%, respectively. In enrolled...

Introduction Total knee arthroplasty is a highly effective treatment for end-stage osteoarthritis, and it usually performed under spinal or general anaesthesia with without surgical tourniquet. Some debate about the preferred mode of regarding patient outcomes remains. The aim this study, which compares tourniquet on total arthroplasty, to determine optimal type regimen assess effect patient’s recovery following arthroplasty. Methods analysis This study randomised, controlled,...

Manipulation under anesthesia (MUA) is the first-choice treatment for stiffness following total knee arthroplasty (TKA) unresponsive to pain management and physiotherapy. Some of predisposing factors patient-reported outcome measures (PROMs) MUA remain poorly studied. We retrospectively investigated etiological risk outcomes MUA.391 TKA patients from a randomized trial comparing use tourniquet (spinal or general) were analyzed, needing identified (MUA group). evaluated in-hospital opioid...